Search Results - "Tan, D X"
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Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity
Published in Obesity reviews (01-03-2011)“…Summary A worldwide increase in the incidence of obesity indicates the unsuccessful battle against this disorder. Obesity and the associated health problems…”
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Melatonin, energy metabolism, and obesity: a review
Published in Journal of pineal research (01-05-2014)“…Melatonin is an old and ubiquitous molecule in nature showing multiple mechanisms of action and functions in practically every living organism. In mammals,…”
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3
Basic mechanisms involved in the anti-cancer effects of melatonin
Published in Current medicinal chemistry (01-12-2010)“…It is commonly accepted that melatonin (N-acetyl-5-methoxytryptamine), the most relevant pineal secretory product, has oncostatic properties in a wide variety…”
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Physics-Based Electromigration Models and Full-Chip Assessment for Power Grid Networks
Published in IEEE transactions on computer-aided design of integrated circuits and systems (01-11-2016)“…This paper presents a novel approach and techniques for physics-based electromigration (EM) assessment in power delivery networks of very large scale…”
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5
The chemistry of melatonin's interaction with reactive species
Published in Journal of pineal research (01-01-2003)“…: Melatonin has been shown to be an effective antioxidant in a number of experimental models both in vitro and in vivo. Considering the data available, it is…”
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Clinical uses of melatonin: evaluation of human trials
Published in Current medicinal chemistry (01-07-2010)“…During the last 20 years, numerous clinical trials have examined the therapeutic usefulness of melatonin in different fields of medicine. The objective of this…”
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Melatonin in the oral cavity: physiological and pathological implications
Published in Journal of periodontal research (01-02-2015)“…Background and Objectives The purpose of this article was to summarize what is known about the function of melatonin in the oral cavity. Material and Methods…”
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Fast Electromigration Immortality Analysis for Multisegment Copper Interconnect Wires
Published in IEEE transactions on computer-aided design of integrated circuits and systems (01-12-2018)“…In this paper, we present a novel and fast electromigration (EM) immortality check for general multisegment interconnect wires. Instead of using current…”
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Analytical Modeling and Characterization of Electromigration Effects for Multibranch Interconnect Trees
Published in IEEE transactions on computer-aided design of integrated circuits and systems (01-11-2016)“…Electromigration (EM) in very large scale integration (VLSI) interconnects has become one of the major reliability issues for current and future VLSI…”
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Accelerating Electromigration Aging: Fast Failure Detection for Nanometer ICs
Published in IEEE transactions on computer-aided design of integrated circuits and systems (01-04-2020)“…For practical testing and detection of electromigration (EM) induced failures in dual damascene copper interconnects, one critical issue is creating stressing…”
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11
GPU-Accelerated Parallel Sparse LU Factorization Method for Fast Circuit Analysis
Published in IEEE transactions on very large scale integration (VLSI) systems (01-03-2016)“…Lower upper (LU) factorization for sparse matrices is the most important computing step for circuit simulation problems. However, parallelizing LU…”
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GPU-based Ising computing for solving max-cut combinatorial optimization problems
Published in Integration (Amsterdam) (01-11-2019)“…In VLSI physical design, many algorithms require the solution of difficult combinatorial optimization problems such as max/min-cut, max-flow problems etc. Due…”
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13
The potential of melatonin in reducing morbidity-mortality after craniocerebral trauma
Published in Journal of pineal research (01-01-2007)“…: Craniocerebral trauma (CCT) is the most frequent cause of morbidity–mortality as a result of an accident. The probable origins and etiologies are…”
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14
Medical implications of melatonin: receptor-mediated and receptor-independent actions
Published in Advances in medical sciences (2007)“…The functional versatility and diversity of melatonin has exceeded everyone's expectations. The evidence is substantial that melatonin has multiple…”
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Executive Function Deficits and Borderline Personality Disorder Symptomatology in a Nonclinical Adult Sample: A Latent Variable Analysis
Published in Brain sciences (26-01-2023)“…While borderline personality disorder (BPD) symptomatology has been studied extensively in clinical populations, the mechanisms underlying its manifestation in…”
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Melatonin inhibits fatty acid-induced triglyceride accumulation in ROS17/2.8 cells: implications for osteoblast differentiation and osteoporosis
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-06-2007)“…Melatonin is produced not only by the pineal gland but by cells of the bone marrow. Moreover, melatonin is known to promote osteogenic differentiation in…”
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The photoperiod, circadian regulation and chronodisruption: the requisite interplay between the suprachiasmatic nuclei and the pineal and gut melatonin
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-06-2011)“…The current scientific literature is replete with investigations providing information on the molecular mechanisms governing the regulation of circadian…”
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Melatonin defeats neurally-derived free radicals and reduces the associated neuromorphological and neurobehavioral damage
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-12-2007)“…Melatonin and its metabolites are potent antioxidants by virtue of their ability to scavenge both oxygen-based and nitrogen-based radicals and intermediates…”
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Drug-mediated ototoxicity and tinnitus: alleviation with melatonin
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-04-2011)“…This review evaluates the published basic science and clinical reports related to the role of melatonin in reducing the side effects of aminoglycosides and the…”
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Fast Analytic Electromigration Analysis for General Multisegment Interconnect Wires
Published in IEEE transactions on very large scale integration (VLSI) systems (01-02-2020)“…Electromigration (EM) is considered to be one of the most important reliability issues for current and future ICs in 10-nm technology and below. In this…”
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