Search Results - "Tan, Chye Ling"

Nicotinamide Metabolism Modulates the Proliferation/Differentiation Balance and Senescence of Human Primary Keratinocytes by Tan, Chye Ling, Chin, Toby, Tan, Christina Yan Ru, Rovito, Holly A., Quek, Ling Shih, Oblong, John E., Bellanger, Sophie

“…Nicotinamide (NAM) is the main precursor of nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for DNA repair, glycolysis, and oxidative…”
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Localization of HPV-18 E2 at mitochondrial membranes induces ROS release and modulates host cell metabolism by Lai, Deborah, Tan, Chye Ling, Gunaratne, Jayantha, Quek, Ling Shih, Nei, Wenlong, Thierry, Françoise, Bellanger, Sophie

“…Papillomavirus E2 proteins are predominantly retained in the nuclei of infected cells, but oncogenic (high-risk) HPV-18 and 16 E2 can shuttle between the host…”
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Stranglehold on the spindle assembly checkpoint: the human papillomavirus E2 protein provokes BUBR1-dependent aneuploidy by Tan, Chye Ling, Teissier, Sébastien, Gunaratne, Jayantha, Quek, Ling Shih, Bellanger, Sophie

“…The Human Papillomavirus (HPV) E2 protein, which inhibits the E6 and E7 viral oncogenes, is believed to have anti-oncogenic properties. Here, we challenge this…”
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Characterization of Der f 22 - a paralogue of the major allergen Der f 2 by Reginald, Kavita, Tan, Chye Ling, Chen, Simin, Yuen, Liling, Goh, Sock Yong, Chew, Fook Tim

“…We previously identified an expressed sequence tag clone, Der f 22, showing 41% amino acid identity to published Der f 2, and show that both genes are possible…”
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The Human Papillomavirus Type 18 E2 Protein Is a Cell Cycle-Dependent Target of the SCFSkp2 Ubiquitin Ligase by Bellanger, Sophie, Tan, Chye Ling, Nei, Wenlong, He, Ping Ping, Thierry, Françoise

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Nicotinamide Prevents UVB- and Oxidative Stress‒Induced Photoaging in Human Primary Keratinocytes by Tan, Christina Yan Ru, Tan, Chye Ling, Chin, Toby, Morenc, Malgorzata, Ho, Chin Yee, Rovito, Holly A., Quek, Ling Shih, Soon, Ai Ling, Lim, John S.Y., Dreesen, Oliver, Oblong, John E., Bellanger, Sophie

“…Nicotinamide (NAM), a NAM adenine dinucleotide precursor, is known for its benefits to skin health. Under standard culture conditions, NAM delays the…”
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Concordance of anaplastic lymphoma kinase (ALK) gene rearrangements between circulating tumor cells and tumor in non-small cell lung cancer by Tan, Chye Ling, Lim, Tse Hui, Lim, Tony Kh, Tan, Daniel Shao-Weng, Chua, Yong Wei, Ang, Mei Kim, Pang, Brendan, Lim, Chwee Teck, Takano, Angela, Lim, Alvin Soon-Tiong, Leong, Man Chun, Lim, Wan-Teck

“…Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC) is routinely evaluated by fluorescent in-situ hybridization (FISH)…”
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Abstract 2370: Depletion of p21-activated kinase 4, PAK4, inhibits cellular proliferation, motility and clonogenicity in oral squamous cell carcinoma by Chung, Felicia F., Tan, Si-Hoey, Raja, Vijay J., Ng, Pei Yuen, Paterson, Ian C., Tan, Chye Ling, Leong, Chee-Onn

“…Abstract Oral squamous cell carcinoma (OSCC) accounts for 90% of all malignancies in the oral cavity, and is often associated with low survival and poor…”
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Abstract 5008: Elucidating HER2 molecular heterogeneity of circulating tumor cells among breast cancer patients by Leong, Man Chun, Lim, Tse Hui, Tan, Chye Ling, Chua, Yong Wei, Lim, Elaine Hsuen, Loh, Kiley Wei Jen, Lee, Guek Eng, Dent, Rebecca, Ng, Raymond Chee Hui, Wu, Andrew, Lim, Wan-Teck, Lim, Alvin Soon-Tiong, Yap, Yoon-Sim

“…Abstract Background: HER2-positive tumors are often associated with poor prognosis, chemo-resistances and some patients eventually develop refractory disease…”
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Molecular detection of ROS1-rearranged circulating tumor cells (CTC) in non-small cell lung cancer (NSCLC) patients by Leong, Man Chun, Lim, Tse Hui, Chua, Yong Wei, Tan, Chye Ling, Tan, Daniel Shao-Weng, Wu, Andrew, Takano, Angela, Lim, Kiat Hon, Lim, Alvin ST, Lim, Wan-Teck

“…Abstract only…”
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Concordance of ALK rearrangement patterns between CTCs and tumour in non-small cell lung cancer (NSCLC) by Tan, Chye Ling, Lim, Wan-Teck, Ng, Quan Sing, Lim, Tse Hui, Lim, Alvin ST, Tan, Daniel SW, Ang, Mei-Kim, Toh, Chee-Keong, Angela, Takano, Lim, Tony KH

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HPV-18 E2^E4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation by Tan, Chye Ling, Gunaratne, Jayantha, Lai, Deborah, Carthagena, Laetitia, Wang, Qian, Xue, Yue Zhen, Quek, Ling Shih, Doorbar, John, Bachelerie, Françoise, Thierry, Françoise, Bellanger, Sophie

“…Abstract The Human Papillomavirus (HPV) E4 is known to be synthesized as an E1^E4 fusion resulting from splice donor and acceptor sites conserved across HPV…”
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Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression by Bellanger, Sophie, Tan, Chye Ling, Xue, Yue Zhen, Teissier, Sébastien, Thierry, Françoise

“…The papillomavirus (PV) E2 proteins have been shown to exert many functions in the viral cycle including pivotal roles in transcriptional regulation and in…”
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HPV-18 E2circumflexE4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation by Tan, Chye Ling, Gunaratne, Jayantha, Lai, Deborah, Carthagena, Laetitia, Wang, Qian, Xue, Yue Zhen, Quek, Ling Shih, Doorbar, John, Bachelerie, Francoise, Thierry, Francoise, Bellanger, Sophie

“…The Human Papillomavirus (HPV) E4 is known to be synthesized as an E1circumflexE4 fusion resulting from splice donor and acceptor sites conserved across HPV…”
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HPV-18 E2 eta 4 chimera: 2 new spliced transcripts and proteins induced by keratinocyte differentiation by Tan, Chye Ling, Gunaratne, Jayantha, Lai, Deborah, Carthagena, Laetitia, Wang, Qian, Xue, Yue Zhen, Quek, Ling Shih, Doorbar, John, Bachelerie, Francoise, Thierry, Francoise, Bellanger, Sophie

“…The Human Papillomavirus (HPV) E4 is known to be synthesized as an E1 eta 4 fusion resulting from splice donor and acceptor sites conserved across HPV types…”
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The Human Papillomavirus Type 18 E2 Protein Is a Cell Cycle-Dependent Target of the SCF Skp2 Ubiquitin Ligase by Bellanger, Sophie, Tan, Chye Ling, Nei, Wenlong, He, Ping Ping, Thierry, Françoise

“…ABSTRACT The human papillomavirus type 18 (HPV-18) E2 gene is inactivated in cervical carcinoma after integration of the viral DNA into the host cellular…”
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Localization of HPV-18 E2 at Mitochondrial Membranes Induces ROS Release and Modulates Host Cell Metabolism: e75625 by Lai, Deborah, Tan, Chye Ling, Gunaratne, Jayantha, Quek, Ling Shih, Nei, Wenlong, Thierry, Francoise, Bellanger, Sophie

“…Papillomavirus E2 proteins are predominantly retained in the nuclei of infected cells, but oncogenic (high-risk) HPV-18 and 16 E2 can shuttle between the host…”
Get full text

Stranglehold on the spindle assembly checkpoint: the human papillomavirus E2 protein provokes BUBR1-dependent aneuploidy by Tan, Chye Ling, Teissier, Sébastien, Gunaratne, Jayantha, Quek, Ling Shih, Bellanger, Sophie

“…The Human Papillomavirus (HPV) E2 protein, which inhibits the E6 and E7 viral oncogenes, is believed to have anti-oncogenic properties. Here, we challenge this…”
Get full text