Search Results - "Tamura, Rodrigo E."
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p53 and metabolism: from mechanism to therapeutics
Published in Oncotarget (04-05-2018)“…The tumor cell changes itself and its microenvironment to adapt to different situations, including action of drugs and other agents targeting tumor control…”
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Editorial: Natural compounds as scaffolds for the discovery of new anti-cancer drugs: Focus on terpenoids and flavonoids
Published in Frontiers in pharmacology (11-08-2022)Get full text
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Potentiation of combined p19Arf and interferon-beta cancer gene therapy through its association with doxorubicin chemotherapy
Published in Scientific reports (10-08-2022)“…Balancing safety and efficacy is a major consideration for cancer treatments, especially when combining cancer immunotherapy with other treatment modalities…”
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Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy
Published in PloS one (12-09-2011)“…Several epidemiological studies have correlated the use of non-steroidal anti-inflammatory drugs (NSAID) with reduced risk of ovarian cancer, the most lethal…”
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5
Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells
Published in Virus research (01-10-2013)“…Characterization of Human Respiratory Syncytial Virus (HRSV) protein interactions with host cell components is crucial to devise antiviral strategies. Viral…”
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Exploration of p53 plus interferon-beta gene transfer for the sensitization of human colorectal cancer cell lines to cell death
Published in Cancer biology & therapy (03-04-2021)“…While treatments for colorectal cancer continue to improve, some 50% of patients succumb within 5 years, pointing to the need for additional therapeutic…”
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S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells
Published in BMC cancer (05-08-2016)“…The S6 Kinase (S6K) proteins are some of the main downstream effectors of the mammalian Target Of Rapamycin (mTOR) and act as key regulators of protein…”
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Bicistronic transfer of CDKN2A and p53 culminates in collaborative killing of human lung cancer cells in vitro and in vivo
Published in Gene therapy (01-02-2020)“…Cancer therapies that target a single protein or pathway may be limited by their specificity, thus missing key players that control cellular proliferation and…”
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Correction: p53 and metabolism: from mechanism to therapeutics
Published in Oncotarget (21-09-2018)“…[This corrects the article DOI: 10.18632/oncotarget.25267.]…”
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GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration
Published in Oncotarget (22-03-2016)“…The epithelium-specific Ets transcription factor, SPDEF, plays a critical role in metastasis of prostate and breast cancer cells. While enhanced SPDEF…”
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Mapping of CD8 T cell epitopes in human respiratory syncytial virus L protein
Published in Intervirology (01-01-2014)“…Since it has been reported that in humans there is a relationship between human respiratory syncytial virus (hRSV)-specific cytotoxic T lymphocytes and symptom…”
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Production of polyclonal antibodies against the human respiratory syncytial virus nucleoprotein and phosphoprotein expressed in Escherichia coli
Published in Protein expression and purification (01-05-2007)“…The nucleoprotein (N) and the phosphoprotein (P) of the human respiratory syncytial virus (HRSV), A2 strain, were cloned into pMAL-c2e vector. The proteins…”
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Gene optimization leads to robust expression of human respiratory syncytial virus nucleoprotein and phosphoprotein in human cells and induction of humoral immunity in mice
Published in Journal of virological methods (01-06-2009)“…Human respiratory syncytial virus (HRSV) is the major pathogen leading to respiratory disease in infants and neonates worldwide. An effective vaccine has not…”
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Expression and purification of a recombinant adenovirus fiber knob in a baculovirus system
Published in Intervirology (01-01-2008)“…To construct a recombinant baculovirus expressing the fiber knob domain of human adenovirus type 2 modified by the insertion of a foreign peptide, purify this…”
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Abstract 3053: Receptor tyrosine kinase AXL as a new target for prostate cancer therapy
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Axl is a receptor tyrosine kinase of the family of TAM receptors (which includes TYRO3 and MER) and plays roles in different types of cancer. It is highly…”
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cdk11p58 regulation of cell cycle progression in cancer development
Published in Clinical cancer research (01-10-2010)“…The Cdk11 protein kinases are members of the cyclin-dependent kinase superfamily. There exist two distinct but closely related human CDK11 genes (p110 and…”
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Combinatorial Effect of Non-Steroidal Anti-inflammatory Drugs and NF-[kappa]B Inhibitors in Ovarian Cancer Therapy
Published in PloS one (12-09-2011)“…Several epidemiological studies have correlated the use of non-steroidal anti-inflammatory drugs (NSAID) with reduced risk of ovarian cancer, the most lethal…”
Get full text
Journal Article