Search Results - "Tamura, Hirosumi"

Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues by Tamura, Hirosumi, Higa, Arisa, Hoshi, Hirotaka, Hiyama, Gen, Takahashi, Nobuhiko, Ryufuku, Masae, Morisawa, Gaku, Yanagisawa, Yuka, Ito, Emi, Imai, Jun-Ichi, Dobashi, Yuu, Katahira, Kiyoaki, Soeda, Shu, Watanabe, Takafumi, Fujimori, Keiya, Watanabe, Shinya, Takagi, Motoki

“…Patient-derived tumor xenograft models represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture;…”
Get full text

LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation by Shibata, Masahiro, Yoshimura, Kentaro, Tamura, Hirosumi, Ueno, Takashi, Nishimura, Taki, Inoue, Takao, Sasaki, Mitsuho, Koike, Masato, Arai, Hiroyuki, Kominami, Eiki, Uchiyama, Yasuo

“…The cytoplasmic lipid droplet (LD) is one of organelles that has a neutral lipid core with a single phospholipid layer. LDs are believed to be generated…”
Get full text

An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids by Takahashi, Nobuhiko, Hoshi, Hirotaka, Higa, Arisa, Hiyama, Gen, Tamura, Hirosumi, Ogawa, Mayu, Takagi, Kosuke, Goda, Kazuhito, Okabe, Naoyuki, Muto, Satoshi, Suzuki, Hiroyuki, Shimomura, Kenju, Watanabe, Shinya, Takagi, Motoki

“…Patient-derived tumor organoids (PDOs) represent a promising preclinical cancer model that better replicates disease, compared with traditional cell culture…”
Get full text

Identification and clinical significance of somatic oncogenic mutations in epithelial ovarian cancer by Watanabe, Takafumi, Nanamiya, Hideaki, Endo, Yuta, Kojima, Manabu, Nomura, Shinji, Furukawa, Shigenori, Soeda, Shu, Tamura, Hirosumi, Ryufuku, Masae, Tanaka, Daisuke, Isogai, Takao, Imai, Jun-Ichi, Watanabe, Shinya, Fujimori, Keiya

“…Epithelial ovarian cancer (EOC) is a heterogeneous disease with diverse clinicopathological features and behaviors, and its heterogeneity may be concerned with…”
Get full text

Construction of in vitro patient-derived tumor models to evaluate anticancer agents and cancer immunotherapy by Takahashi, Nobuhiko, Higa, Arisa, Hiyama, Gen, Tamura, Hirosumi, Hoshi, Hirotaka, Dobashi, Yuu, Katahira, Kiyoaki, Ishihara, Hiroya, Takagi, Kosuke, Goda, Kazuhito, Okabe, Naoyuki, Muto, Satoshi, Suzuki, Hiroyuki, Shimomura, Kenju, Watanabe, Shinya, Takagi, Motoki

“…An assay system using patient-derived tumor models represents a promising preclinical cancer model that replicates the disease better than traditional cell…”
Get full text

Atg9A Protein, an Autophagy-related Membrane Protein, Is Localized in the Neurons of Mouse Brains by Tamura, Hirosumi, Shibata, Masahiro, Koike, Masato, Sasaki, Mitsuho, Uchiyama, Yasuo

“…Old and unneeded intracellular macromolecules are delivered through autophagy to lysosomes that degrade macromolecules into bioactive monomers such as amino…”
Get full text

Distribution of autophagy related transmembrane protein Atg9A by Tamura, Hirosumi, Uchiyama, Yasuo

Get full text

Establishment and Characterization of a Novel Human Clear-cell Sarcoma of Soft-tissue Cell Line, RSAR001, Derived from Pleural Effusion of a Patient with Pleural Dissemination by Hakozaki, Michiyuki, Tamura, Hirosumi, Dobashi, Yuu, Yoshida, Aki, Kato, Kouki, Tajino, Takahiro, Yamada, Hitoshi, Kaneuchi, Yoichi, Katahira, Kiyoaki, Ezaki, Junji, Waguri, Satoshi, Konno, Shinichi, Watanabe, Shinya

“…Clear cell sarcoma (CCS) of soft tissue is exceedingly rare and frequently exhibits aggressive behavior. Toward the goals of improving the aggressive course…”
Get full text

A Blood-based Gene-expression Scoring System for Cancer Screening in Patients With Branch-duct Intraductal Papillary Mucinous Neoplasms by Suzuki, Rei, Tamura, Hirosumi, Honma, Reiko, Konno, Naoki, Irie, Hiroki, Takagi, Tadayuki, Sugimoto, Mitsuru, Asama, Hiroyuki, Sato, Yuki, Yoshinori, Okubo, Nakamura, Jun, Takasumi, Mika, Kato, Tsunetaka, Hashimoto, Minami, Hikichi, Takuto, Imai, Jun-Ichi, Watanabe, Shinya, Ohira, Hiromasa

“…Background: In patients with branch-duct intraductal papillary mucinous neoplasms (BD-IPMN), we aimed to develop a novel blood-based biomarker utilizing a…”
Get full text

A novel gene expression scoring system for accurate diagnosis of basaloid squamous cell carcinoma of the esophagus by Tada, Takeshi, Honma, Reiko, Imai, Jun-Ichi, Saze, Zenichiro, Kogure, Michihiko, Marubashi, Shigeru, Tasaki, Kazuhiro, Unakami, Masamitu, Ezaki, Junji, Tamura, Hirosumi, Nishikawa, Akira, Hashimoto, Yuko, Waguri, Satoshi, Watanabe, Shinya, Gotoh, Mitsukazu

“…Basaloid squamous cell carcinoma of the esophagus (BSCE) is a rare variant of squamous cell carcinoma that is difficult to distinguish from other carcinomas by…”
Get full text

Family with sequence similarity 83, member B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild-type epidermal growth factor receptor by Yamaura, Takumi, Ezaki, Junji, Okabe, Naoyuki, Takagi, Hironori, Ozaki, Yuki, Inoue, Takuya, Watanabe, Yuzuru, Fukuhara, Mitsuro, Muto, Satoshi, Matsumura, Yuki, Hasegawa, Takeo, Hoshino, Mika, Osugi, Jun, Shio, Yutaka, Waguri, Satoshi, Tamura, Hirosumi, Imai, Jun-Ichi, Ito, Emi, Yanagisawa, Yuka, Honma, Reiko, Watanabe, Shinya, Suzuki, Hiroyuki

“…Lung adenocarcinoma (ADC) patients with tumors that harbor no targetable driver gene mutation, such as epidermal growth factor receptor ( ) gene mutations,…”
Get full text

FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma by OKABE, NAOYUKI, EZAKI, JUNJI, YAMAURA, TAKUMI, MUTO, SATOSHI, OSUGI, JUN, TAMURA, HIROSUMI, IMAI, JUN-ICHI, ITO, EMI, YANAGISAWA, YUKA, HONMA, REIKO, GOTOH, MITSUKAZU, WATANABE, SHINYA, WAGURI, SATOSHI, SUZUKI, HIROYUKI

“…Personalized therapy for non-small cell lung cancer (NSCLC), particularly lung adenocarcinoma, has recently been significantly improved by the discovery of…”
Get full text

Atg9A, an autophagy-related membrane protein, is localized in neurons of mouse brain by Tamura, Hirosumi, Shibata, Masahiro, Koike, Masato, Sasaki, Mituho, Uchiyama, Yasuo

Get full text

Family with sequence similarity 83, member�B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild‑type epidermal growth factor receptor by Yamaura, Takumi, Ezaki, Junji, Okabe, Naoyuki, Takagi, Hironori, Ozaki, Yuki, Inoue, Takuya, Watanabe, Yuzuru, Fukuhara, Mitsuro, Muto, Satoshi, Matsumura, Yuki, Hasegawa, Takeo, Hoshino, Mika, Osugi, Jun, Shio, Yutaka, Waguri, Satoshi, Tamura, Hirosumi, Imai, Jun‑Ichi, Ito, Emi, Yanagisawa, Yuka, Honma, Reiko, Watanabe, Shinya, Suzuki, Hiroyuki

Get full text