Search Results - "Tamura, Akitoshi"

ATP/ADP biosensor organoids for drug nephrotoxicity assessment by Susa, Koichiro, Kobayashi, Kenichi, Galichon, Pierre, Matsumoto, Takuya, Tamura, Akitoshi, Hiratsuka, Ken, Gupta, Navin R, Yazdi, Iman K, Bonventre, Joseph V, Morizane, Ryuji

“…Drug nephrotoxicity is a common healthcare problem in hospitalized patients and a major limitation during drug development. Multi-segmented kidney organoids…”
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Increased c‐Myc activity and DNA damage in hematopoietic progenitors precede myeloproliferative disease in Spa‐1‐deficiency by Tanaka, Hiroki, Tamura, Akitoshi, Sekai, Miho, Hamazaki, Yoko, Minato, Nagahiro

“…Mice deficient for Spa‐1 encoding Rap GTPase‐activating protein develop myeloproliferative disorder (MPD) of late onset with frequent blast crises. The…”
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Rap1 Signal Controls B Cell Receptor Repertoire and Generation of Self-Reactive B1a Cells by Ishida, Daisuke, Su, Li, Tamura, Akitoshi, Katayama, Yoshinori, Kawai, Yohei, Wang, Shu-Fang, Taniwaki, Masafumi, Hamazaki, Yoko, Hattori, Masakazu, Minato, Nagahiro

“…We previously reported that the mice deficient for SPA-1, a Rap1 GTPase-activating protein, developed hematopoietic stem cell disorders. Here, we demonstrate…”
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The effects of clobazam treatment in rats on the expression of genes and proteins encoding glucronosyltransferase 1A/2B (UGT1A/2B) and multidrug resistance‐associated protein-2 (MRP2), and development of thyroid follicular cell hypertrophy by Miyawaki, Izuru, Tamura, Akitoshi, Matsumoto, Izumi, Inada, Hiroshi, Kunimatsu, Takeshi, Kimura, Juki, Funabashi, Hitoshi

“…Clobazam (CLB) is known to increase hepatobiliary thyroxine (T4) clearance in Sprague–Dawley (SD) rats, which results in hypothyroidism followed by thyroid…”
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Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans by Tamura, Akitoshi, Miyawaki, Izuru, Yamada, Toru, Kimura, Juki, Funabashi, Hitoshi

“…It is important to evaluate the potential of drug hypersensitivity as well as other adverse effects during the preclinical stage of the drug development…”
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Increased caMyc activity and DNA damage in hematopoietic progenitors precede myeloproliferative disease in Spaa1adeficiency by Tanaka, Hiroki, Tamura, Akitoshi, Sekai, Miho, Hamazaki, Yoko, Minato, Nagahiro

“…Mice deficient for Spa-1 encoding Rap GTPase-activating protein develop myeloproliferative disorder (MPD) of late onset with frequent blast crises. The…”
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g-Factor of the 27/2+ isomeric state in 149Tb by ADACHI, M, TAMURA, A, KOUGUCHI, M, TAKANASHI, H, TAKETANI, H

“…The g-factor of the 27/2+ isomeric state in 149Tb has been measured with a TIPAD method through the 141Pr(12C, 4nγ)149Tb reaction. With the meanlife τ of…”
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g -Factor of the 27/2 + Isomeric State in 149 Tb by Adachi, Minoru, Tamura, Akitoshi, Kouguchi, Masanari, Takanashi, Hidehiko, Taketani, Hiroshi

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