Search Results - "Tamuhla, Tsaone"

An e-consent framework for tiered informed consent for human genomic research in the global south, implemented as a REDCap template by Tamuhla, Tsaone, Tiffin, Nicki, Allie, Taryn

“…Research involving human participants requires their consent, and it is common practice to capture consent information on paper and store those hard copies,…”
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Diabetes in a TB and HIV-endemic South African population: Analysis of a virtual cohort using routine health data by Tamuhla, Tsaone, Dave, Joel A, Raubenheimer, Peter, Tiffin, Nicki

“…It is widely accepted that people living with diabetes (PLWD) are at increased risk of infectious disease, yet there is a paucity of epidemiology studies on…”
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Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions by Fatumo, Segun, Sathan, Dassen, Samtal, Chaimae, Isewon, Itunuoluwa, Tamuhla, Tsaone, Soremekun, Chisom, Jafali, James, Panji, Sumir, Tiffin, Nicki, Fakim, Yasmina Jaufeerally

“…Early identification of genetic risk factors for complex diseases can enable timely interventions and prevent serious outcomes, including mortality. While the…”
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A framework for the promotion of ethical benefit sharing in health research by Bedeker, Anja, Nichols, Michelle, Allie, Taryn, Tamuhla, Tsaone, van Heusden, Peter, Olorunsogbon, Olorunyomi, Tiffin, Nicki

“…There is an increasing recognition of the importance of including benefit sharing in research programmes in order to ensure equitable and just distribution of…”
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Multiple modes of data sharing can facilitate secondary use of sensitive health data for research by Tamuhla, Tsaone, Lulamba, Eddie T, Mutemaringa, Themba, Tiffin, Nicki

“…Evidence-based healthcare relies on health data from diverse sources to inform decision-making across different domains, including disease prevention,…”
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The PHA4GE Microbial Data-Sharing Accord: establishing baseline consensus microbial data-sharing norms to facilitate cross-sectoral collaboration by Griffiths, Emma J, van Heusden, Peter, Tamuhla, Tsaone, Lulamba, Eddie T, Bedeker, Anja, Nichols, Michelle, Christoffels, Alan, Tiffin, Nicki

“…Microbial data sharing underlies evidence-based microbial research, as well as pathogen surveillance and analysis essential to public health. While the need…”
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Routine health data describe adherence and persistence patterns for oral diabetes medication for a virtual cohort in the Khayelitsha sub-district of Cape Town, South Africa by Tamuhla, Tsaone, Raubenheimer, Peter, Dave, Joel A, Tiffin, Nicki

“…Type 2 diabetes mellitus (T2DM) is managed with combined lifestyle modifications and antidiabetic drugs, but people on treatment often fail to reach glycaemic…”
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Accessing HIV care may lead to earlier ascertainment of comorbidities in health care clients in Khayelitsha, Cape Town by Osei-Yeboah, Richard, Tamuhla, Tsaone, Ngwenya, Olina, Tiffin, Nicki

“…Successful antiretroviral rollout in South Africa has greatly increased the health of the HIV-positive population, and morbidity and mortality in PLHIV can…”
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Developing Clinical Phenotype Data Collection Standards for Research in Africa by Zass, Lyndon, Johnston, Katherine, Benkahla, Alia, Chaouch, Melek, Kumuthini, Judit, Radouani, Fouzia, Mwita, Liberata Alexander, Alsayed, Nihad, Allie, Taryn, Sathan, Dassen, Masamu, Upendo, Seuneu Tchamga, Milaine Sergine, Tamuhla, Tsaone, Samtal, Chaimae, Nembaware, Victoria, Gill, Zoe, Ahmed, Samah, Hamdi, Yosr, Fadlelmola, Faisal, Tiffin, Nicki, Mulder, Nicola

“…Modern biomedical research is characterised by its high-throughput and interdisciplinary nature. Multiproject and consortium-based collaborations requiring…”
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The effect of sputum quality and volume on the yield of bacteriologically-confirmed TB by Xpert MTB/RIF and smear by Zimba, Onani, Tamuhla, Tsaone, Basotli, Joyce, Letsibogo, Gaoraelwe, Pals, Sherri, Mathebula, Unami, Mathoma, Anikie, Serumola, Christopher, Ramogale, Kitso, Boyd, Rosanna, Tran, Tiffany, Finlay, Alyssa, Auld, Andrew, Date, Anand, Alexander, Heather, Chihota, Violet, Agizew, Tefera

“…The World Health Organization endorsed (2010) the use of Xpert MTB/RIF and countries are shifting from smear microscopy (smear)-based to Xpert MTB/RIF-based…”
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SufT is required for growth of Mycobacterium smegmatis under iron limiting conditions by Tamuhla, Tsaone, Joubert, Lydia, Willemse, Danicke, Williams, Monique J

“…Iron-sulphur (FeS) clusters are versatile cofactors required for a range of biological processes within cells. Due to the reactive nature of the constituent…”
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Diagnosis of pulmonary tuberculosis and assessment of treatment response through analyses of volatile compound patterns in exhaled breath samples by Zetola, Nicola M, Modongo, Chawangwa, Matsiri, Ogopotse, Tamuhla, Tsaone, Mbongwe, Bontle, Matlhagela, Keikantse, Sepako, Enoch, Catini, Alexandro, Sirugo, Giorgio, Martinelli, Eugenio, Paolesse, Roberto, Di Natale, Corrado

“…Summary Objectives We determined the performance of a sensor array (an electronic nose) made of 8 metalloporphyrins coated quartz microbalances sensors for the…”
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Risk factors for COVID-19 hospitalisation and death in people living with diabetes: A virtual cohort study from the Western Cape Province, South Africa by Dave, Joel A., Tamuhla, Tsaone, Tiffin, Nicki, Levitt, Naomi S., Ross, Ian L., Toet, William, Davies, Mary-Ann, Boulle, Andrew, Coetzee, Ankia, Raubenheimer, Peter J.

“…COVID-19 outcomes and risk factors, including comorbidities and medication regimens, in people living with diabetes (PLWD) are poorly defined for low- and…”
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Coronavirus Host Genetics South Africa (COHG-SA) database-a variant database for gene regions associated with SARS-CoV-2 outcomes by Barmania, Fatima, Mellet, Juanita, Ryder, Megan A, Ford, Graeme, Herd, Candice L, Tamuhla, Tsaone, Hendricks, Candice, Giles, Rachel, Kalua, Thumbiko, Joubert, Fourie, Tiffin, Nicki, Pepper, Michael S

“…The SARS-CoV-2 virus is responsible for the COVID-19 global public health emergency, and the disease it causes is highly variable in its clinical presentation…”
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Accessing HIV care may lead to earlier ascertainment of comorbidities in health care clients in Khayelitsha, Cape Town by Richard Osei-Yeboah, Tsaone Tamuhla, Olina Ngwenya, Nicki Tiffin

“…Successful antiretroviral rollout in South Africa has greatly increased the health of the HIV-positive population, and morbidity and mortality in PLHIV can…”
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Implementation of a genotyped African population cohort, with virtual follow-up: A feasibility study in the Western Cape Province, South Africa by Tamuhla, Tsaone, Coussens, Anna K, Abrahams, Maleeka, Blumenthal, Melissa J, Lakay, Francisco, Wilkinson, Robert J, Riou, Catherine, Raubenheimer, Peter, Dave, Joel A, Tiffin, Nicki

“…Background There is limited knowledge regarding African genetic drivers of disease due to prohibitive costs of large-scale genomic research in Africa. Methods…”
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Identification of a Large Pool of Microorganisms with an Array of Porphyrin Based Gas Sensors by Zetola, Nicola M, Modongo, Chawangwa, Mathlagela, Keikantse, Sepako, Enoch, Matsiri, Ogopotse, Tamuhla, Tsaone, Mbongwe, Bontle, Martinelli, Eugenio, Sirugo, Giorgio, Paolesse, Roberto, Di Natale, Corrado

“…The association between volatile compounds (VCs) and microorganisms, as demonstrated by several studies, may offer the ground for a rapid identification of…”
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Molecular, Spatial, and Field Epidemiology Suggesting TB Transmission in Community, Not Hospital, Gaborone, Botswana by Surie, Diya, Fane, Othusitse, Finlay, Alyssa, Ogopotse, Matsiri, Tobias, James L, Click, Eleanor S, Modongo, Chawangwa, Zetola, Nicola M, Moonan, Patrick K, Oeltmann, John E

“…During 2012-2015, 10 of 24 patients infected with matching genotypes of Mycobacterium tuberculosis received care at the same hospital in Gaborone, Botswana…”
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Multimorbidity research in Sub-Saharan Africa: Proceedings of an interdisciplinary workshop by Banda, Gift T., Bosire, Edna, Bunn, Christopher, Chandler, Clare I.R., Chikumbu, Edith, Chiwanda, Jonathan, Dixon, Justin, Ferrand, Rashida A., Kengne, Andre-Pascal, Limbani, Felix, Mendenhall, Emily, Morton, Ben, Moshabela, Mosa, Peer, Nasheeta, Salimu, Sangwani, Silman, Alan, Simiyu, Ibrahim G., Spencer, Stephen A., Tamuhla, Tsaone, Tiffin, Nicki, Yongolo, Nateiya M.

“…As life expectancies rise globally, the number of people living with multiple chronic health conditions – commonly referred to as ‘multimorbidity’ – is rising…”
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Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model by Dixon, Justin, Morton, Ben, Nkhata, Misheck J, Silman, Alan, Simiyu, Ibrahim G, Spencer, Stephen A, Van Pinxteren, Myrna, Bunn, Christopher, Calderwood, Claire, Chandler, Clare I R, Chikumbu, Edith, Crampin, Amelia C, Hurst, John R, Jobe, Modou, Kengne, Andre Pascal, Levitt, Naomi S, Moshabela, Mosa, Owolabi, Mayowa, Peer, Nasheeta, Phiri, Nozgechi, Singh, Sally J, Tamuhla, Tsaone, Tembo, Mandikudza, Tiffin, Nicki, Worrall, Eve, Yongolo, Nateiya M, Banda, Gift T, Bickton, Fanuel, Bilungula, Abbi-Monique Mamani, Bosire, Edna, Chawani, Marlen S, Chinoko, Beatrice, Chisala, Mphatso, Chiwanda, Jonathan, Drew, Sarah, Farrant, Lindsay, Ferrand, Rashida A, Gondwe, Mtisunge, Gregson, Celia L, Harding, Richard, Kajungu, Dan, Kasenda, Stephen, Katagira, Winceslaus, Kwaitana, Duncan, Mendenhall, Emily, Mensah, Adwoa Bemah Boamah, Mnenula, Modai, Mupaza, Lovemore, Mwakasungula, Maud, Nakanga, Wisdom, Ndhlovu, Chiratidzo, Nkhoma, Kennedy, Nkoka, Owen, Opare-Lokko, Edwina Addo, Phulusa, Jacob, Price, Alison, Rylance, Jamie, Salima, Charity, Salimu, Sangwani, Sturmberg, Joachim, Vale, Elizabeth, Limbani, Felix

“…Multimorbidity is an emerging challenge for health systems globally. It is commonly defined as the co-occurrence of two or more chronic conditions in one…”
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