Search Results - "Tamplin, J"

NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells by Uenishi, Gene I., Jung, Ho Sun, Kumar, Akhilesh, Park, Mi Ae, Hadland, Brandon K., McLeod, Ethan, Raymond, Matthew, Moskvin, Oleg, Zimmerman, Catherine E., Theisen, Derek J., Swanson, Scott, J. Tamplin, Owen, Zon, Leonard I., Thomson, James A., Bernstein, Irwin D., Slukvin, Igor I.

“…NOTCH signaling is required for the arterial specification and formation of hematopoietic stem cells (HSCs) and lympho-myeloid progenitors in the embryonic…”
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Neural Crossroads in the Hematopoietic Stem Cell Niche by Agarwala, Sobhika, Tamplin, Owen J.

“…The hematopoietic stem cell (HSC) niche supports steady-state hematopoiesis and responds to changing needs during stress and disease. The nervous system is an…”
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Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche by Tamplin, Owen J., Durand, Ellen M., Carr, Logan A., Childs, Sarah J., Hagedorn, Elliott J., Li, Pulin, Yzaguirre, Amanda D., Speck, Nancy A., Zon, Leonard I.

“…Hematopoietic stem and progenitor cells (HSPCs) can reconstitute and sustain the entire blood system. We generated a highly specific transgenic reporter of…”
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Making fish a little more human: a zebrafish hematopoietic xenotransplant model is improved by the expression of human cytokines by Tamplin, Owen J

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Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish by Mosimann, Christian, Kaufman, Charles K, Li, Pulin, Pugach, Emily K, Tamplin, Owen J, Zon, Leonard I

“…Molecular genetics approaches in zebrafish research are hampered by the lack of a ubiquitous transgene driver element that is active at all developmental…”
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A systematic review and meta-analysis of the effects of respiratory muscle training on pulmonary function in tetraplegia by Tamplin, J, Berlowitz, D J

“…Study design: Systematic review Objectives: To determine the effect of respiratory muscle training (RMT) on pulmonary function in tetraplegia. Methods: A…”
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The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells by Shao, Lijian, Elujoba-Bridenstine, Adedamola, Zink, Katherine E., Sanchez, Laura M., Cox, Brian J., Pollok, Karen E., Sinn, Anthony L., Bailey, Barbara J., Sims, Emily C., Cooper, Scott H., Broxmeyer, Hal E., Pajcini, Kostandin V., Tamplin, Owen J.

“…Hematopoietic and nervous systems are linked via innervation of bone marrow (BM) niche cells. Hematopoietic stem/progenitor cells (HSPCs) express…”
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Discovery of the youngest sex chromosomes reveals first case of convergent co-option of ancestral autosomes in turtles by Montiel, E. E., Badenhorst, D., Tamplin, J., Burke, R. L., Valenzuela, N.

“…Most turtle species possess temperature-dependent sex determination (TSD), but genotypic sex determination (GSD) has evolved multiple times independently from…”
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Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development by McCann, Matthew R, Tamplin, Owen J, Rossant, Janet, Séguin, Cheryle A

“…Back pain related to intervertebral disc degeneration is the most common musculoskeletal problem, with a lifetime prevalence of 82%. The lack of effective…”
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The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish by Bornhorst, Dorothee, Hejjaji, Amulya V., Steuter, Lena, Woodhead, Nicole M., Maier, Paul, Gentile, Alessandra, Alhajkadour, Alice, Santis Larrain, Octavia, Weber, Michael, Kikhi, Khrievono, Guenther, Stefan, Huisken, Jan, Tamplin, Owen J., Stainier, Didier Y. R., Gunawan, Felix

“…The contribution of endocardial cells (EdCs) to the hematopoietic lineages has been strongly debated. Here, we provide evidence that in zebrafish, the…”
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Live Imaging and Genetic Analysis of Mouse Notochord Formation Reveals Regional Morphogenetic Mechanisms by Yamanaka, Yojiro, Tamplin, Owen J., Beckers, Anja, Gossler, Achim, Rossant, Janet

“…The node and notochord have been extensively studied as signaling centers in the vertebrate embryo. The morphogenesis of these tissues, particularly in mouse,…”
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Adenosine signaling promotes hematopoietic stem and progenitor cell emergence by Jing, Lili, Tamplin, Owen J, Chen, Michael J, Deng, Qing, Patterson, Shenia, Kim, Peter G, Durand, Ellen M, McNeil, Ashley, Green, Julie M, Matsuura, Shinobu, Ablain, Julien, Brandt, Margot K, Schlaeger, Thorsten M, Huttenlocher, Anna, Daley, George Q, Ravid, Katya, Zon, Leonard I

“…Hematopoietic stem cells (HSCs) emerge from aortic endothelium via the endothelial-to-hematopoietic transition (EHT). The molecular mechanisms that initiate…”
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CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment by Blaser, Bradley W, Moore, Jessica L, Hagedorn, Elliott J, Li, Brian, Riquelme, Raquel, Lichtig, Asher, Yang, Song, Zhou, Yi, Tamplin, Owen J, Binder, Vera, Zon, Leonard I

“…The microenvironment is an important regulator of hematopoietic stem and progenitor cell (HSPC) biology. Recent advances marking fluorescent HSPCs have allowed…”
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Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy by Agarwala, Sobhika, Kim, Keun-Young, Phan, Sebastien, Ju, Saeyeon, Kong, Ye Eun, Castillon, Guillaume A, Bushong, Eric A, Ellisman, Mark H, Tamplin, Owen J

“…The blood system is supported by hematopoietic stem and progenitor cells (HSPCs) found in a specialized microenvironment called the niche. Many different niche…”
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Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord by Tamplin, Owen J., Cox, Brian J., Rossant, Janet

“…The node and notochord are key tissues required for patterning of the vertebrate body plan. Understanding the gene regulatory network that drives their…”
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Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives by Tamplin, Owen J, Kinzel, Doris, Cox, Brian J, Bell, Christine E, Rossant, Janet, Lickert, Heiko

“…The Spemann/Mangold organizer is a transient tissue critical for patterning the gastrula stage vertebrate embryo and formation of the three germ layers…”
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Dopamine motivates stem cells for reward by Tamplin, Owen J.

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Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression by Anderson, Heidi, Patch, Taylor C., Reddy, Pavankumar N.G., Hagedorn, Elliott J., Kim, Peter G., Soltis, Kathleen A., Chen, Michael J., Tamplin, Owen J., Frye, Maike, MacLean, Glenn A., Hübner, Kathleen, Bauer, Daniel E., Kanki, John P., Vogin, Guillaume, Huston, Nicholas C., Nguyen, Minh, Fujiwara, Yuko, Paw, Barry H., Vestweber, Dietmar, Zon, Leonard I., Orkin, Stuart H., Daley, George Q., Shah, Dhvanit I.

“…Rare endothelial cells in the aorta-gonad-mesonephros (AGM) transition into hematopoietic stem cells (HSCs) during embryonic development. Lineage tracing…”
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Remodel your way to fetal hematopoiesis by Tamplin, Owen J.

“…In this issue of Blood , the study by Ding et al 1 describes a novel role for the chromatin remodeling factor smarca5 during the development of hematopoietic…”
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Blood Flow: Metalloproteases Cut Loose in Primitive Erythrocytes by Tamplin, Owen J., Zon, Leonard I.

“…Little is known about how blood begins to flow during development. A new study shows that release of primitive blood cells in the zebrafish embryo is…”
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