Search Results - "Tamminen, Toni"

AAV2 and AAV9 tropism and transgene expression in the mouse eye and major tissues after intravitreal and subretinal delivery by Koponen, Sanna, Kokki, Emmi, Tamminen, Toni, Ylä-Herttuala, Seppo

“…Introduction: The eye is an excellent target for gene therapy because of its anatomical features. Gene therapy to treat ocular disorders relies on efficient…”
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A 15month follow‐up study characterizing the progression of retinal pathology and visual loss in CLN3 ex7/8 mice by Torsti, Tommi, Toropainen, Elisa, Tamminen, Toni, Kauppinen, Anu, Kaarniranta, Kai, sberg, Markus M

“…Aims/Purpose: Juvenile form of neuronal ceroid lipofuscinosis is a is a rare neurological disease that manifests in childhood, by progressive visual…”
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A 15 month follow‐up study characterizing the progression of retinal pathology and visual loss in CLN3 ex7/8 mice by Torsti, Tommi, Toropainen, Elisa, Tamminen, Toni, Kauppinen, Anu, Kaarniranta, Kai, Forsberg, Markus M.

“…Aims/Purpose: Juvenile form of neuronal ceroid lipofuscinosis is a is a rare neurological disease that manifests in childhood, by progressive visual…”
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Increased secretory autophagy in retinal pigment epithelial cells of the 5xFAD mice by Ruuth, Johanna, Tamminen, Toni, Toropainen, Elisa, Koskela, Ali, Tanila, Heikki, Kaarniranta, Kai

“…Purpose: Disturbed proteostasis and oxidative stress have a key role in Alzheimer's disease and age‐related macular degeneration pathology. Constant oxidative…”
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Secretory autophagy is increased in 5xFAD mice by Ruuth, Johanna, Tamminen, Toni, Toropainen, Elisa, Koskela, Ali, Korhonen, Paula, Tanila, Heikki, Malm, Tarja, Kaarniranta, Kai

“…Purpose: Chronic oxidative stress, disturbed proteostasis and increased protein aggregation are key hallmarks in Alzheimer's disease and age‐related macular…”
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5xFAD mouse model develops visual dysfunction together with protein aggregation by Ruuth, Johanna, Tamminen, Toni, Toropainen, Elisa, Koskela, Ali, Tanila, Heikki, Malm, Tarja, Kaarniranta, Kai

“…Purpose Disturbed proteostasis and protein aggregation have a key role in Alzheimer´s disease and age‐related macular degeneration pathology. In this study, we…”
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Circadian Control and Pinosylvin Treatment in the Disease Model of Age‐related Macular Degeneration by Tamminen, Toni, Koskela, Ali, Toropainen, Elisa, Pitkänen, Marja, Viiri, Johanna, Paterno, Jussi, Seppänen, Anne, Koskelainen, Ari, Kaarniranta, Kai

“…Purpose Circadian clocks in the eye are critical for normal visual function and they relate to periodical renewal of photoreceptor outer segments as well as…”
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Pinosylvin extract Retinari™ sustains electrophysiological function, prevents thinning of retina and enhances cellular response to oxidative stress in NFE2L2 knock‐out mice by Tamminen, Toni, Koskela, Ali, Toropainen, Elisa, Gurubaran, Iswariyaraja Sridevi, Winiarczyk, Mateusz, Liukkonen, Mikko, Paterno, Jussi J., Lackman, Petri, Sadeghi, Amir, Viiri, Johanna, Hyttinen, Juha M. T., Koskelainen, Ari, Kaarniranta, Kai

“…Purpose Chronic oxidative stress eventually leads to protein aggregation in combination with impaired autophagy, which has been observed in age‐related macular…”
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Pinosylvin Extract Retinari™ Sustains Electrophysiological Function, Prevents Thinning of Retina, and Enhances Cellular Response to Oxidative Stress in NFE2L2 Knockout Mice by Tamminen, Toni, Koskela, Ali, Toropainen, Elisa, Gurubaran, Iswariyaraja Sridevi, Winiarczyk, Mateusz, Liukkonen, Mikko, Paterno, Jussi J., Lackman, Petri, Sadeghi, Amir, Viiri, Johanna, Hyttinen, Juha M. T., Koskelainen, Ari, Kaarniranta, Kai

“…Chronic oxidative stress eventually leads to protein aggregation in combination with impaired autophagy, which has been observed in age-related macular…”
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Sequential Monte Carlo for Bayesian matching of objects with occlusions by Tamminen, T., Lampinen, J.

“…We consider the problem of locating instances of a known object in a novel scene by matching the fiducial features of the object. The appearance of the…”
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