Search Results - "Tammie L. Volkman"

Sympathetic β1-adrenergic signaling contributes to regulation of human bone metabolism by Khosla, Sundeep, Drake, Matthew T, Volkman, Tammie L, Thicke, Brianne S, Achenbach, Sara J, Atkinson, Elizabeth J, Joyner, Michael J, Rosen, Clifford J, Monroe, David G, Farr, Joshua N

“…Evidence from rodent studies indicates that the sympathetic nervous system (SNS) regulates bone metabolism, principally via β2-adrenergic receptors (β2-ARs)…”
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Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease by Hickson, LaTonya J., Langhi Prata, Larissa G.P., Bobart, Shane A., Evans, Tamara K., Giorgadze, Nino, Hashmi, Shahrukh K., Herrmann, Sandra M., Jensen, Michael D., Jia, Qingyi, Jordan, Kyra L., Kellogg, Todd A., Khosla, Sundeep, Koerber, Daniel M., Lagnado, Anthony B., Lawson, Donna K., LeBrasseur, Nathan K., Lerman, Lilach O., McDonald, Kathleen M., McKenzie, Travis J., Passos, João F., Pignolo, Robert J., Pirtskhalava, Tamar, Saadiq, Ishran M., Schaefer, Kalli K., Textor, Stephen C., Victorelli, Stella G., Volkman, Tammie L., Xue, Ailing, Wentworth, Mark A., Wissler Gerdes, Erin O., Zhu, Yi, Tchkonia, Tamara, Kirkland, James L.

“…Senescent cells, which can release factors that cause inflammation and dysfunction, the senescence-associated secretory phenotype (SASP), accumulate with…”
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Determinants of Bone Material Strength and Cortical Porosity in Patients with Type 2 Diabetes Mellitus by Samakkarnthai, Parinya, Sfeir, Jad G, Atkinson, Elizabeth J, Achenbach, Sara J, Wennberg, Paul W, Dyck, Peter J, Tweed, Amanda J, Volkman, Tammie L, Amin, Shreyasee, Farr, Joshua N, Vella, Adrian, Drake, Matthew T, Khosla, Sundeep

“…Abstract Context Reduced bone material strength index (BMSi) and increased cortical porosity (CtPo) have emerged as potentially contributing to fracture risk…”
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Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial by Farr, Joshua N., Atkinson, Elizabeth J., Achenbach, Sara J., Volkman, Tammie L., Tweed, Amanda J., Vos, Stephanie J., Ruan, Ming, Sfeir, Jad, Drake, Matthew T., Saul, Dominik, Doolittle, Madison L., Bancos, Irina, Yu, Kai, Tchkonia, Tamara, LeBrasseur, Nathan K., Kirkland, James L., Monroe, David G., Khosla, Sundeep

“…Preclinical evidence demonstrates that senescent cells accumulate with aging and that senolytics delay multiple age-related morbidities, including bone loss…”
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Development and Application of Mass Spectroscopy Assays for Nε-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes by O'Grady, Katherine L, Khosla, Sundeep, Farr, Joshua N, Bondar, Olga P, Atkinson, Elizabeth J, Achenbach, Sara J, Eckhardt, Brittany A, Thicke, Brianne S, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Hines, Jolaine M, Singh, Ravinder J

“…Advanced glycation end products (AGEs) are formed via the nonenzymatic glycation of sugars with amino acids. Two AGEs, Nε-(1-carboxymethyl)-L-Lysine (CML) and…”
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Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456 by Hickson, LaTonya J., Langhi Prata, Larissa G.P., Bobart, Shane A., Evans, Tamara K., Giorgadze, Nino, Hashmi, Shahrukh K., Herrmann, Sandra M., Jensen, Michael D., Jia, Qingyi, Jordan, Kyra L., Kellogg, Todd A., Khosla, Sundeep, Koerber, Daniel M., Lagnado, Anthony B., Lawson, Donna K., LeBrasseur, Nathan K., Lerman, Lilach O., McDonald, Kathleen M., McKenzie, Travis J., Passos, João F., Pignolo, Robert J., Pirtskhalava, Tamar, Saadiq, Ishran M., Schaefer, Kalli K., Textor, Stephen C., Victorelli, Stella G., Volkman, Tammie L., Xue, Ailing, Wentworth, Mark A., Wissler Gerdes, Erin O., Allison, David B., Dickinson, Stephanie L., Ejima, Keisuke, Atkinson, Elizabeth J., Lenburg, Marc, Zhu, Yi, Tchkonia, Tamara, Kirkland, James L.

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SUN-LB68 Advanced Glycation Endproducts Are Associated With Worse Bone Material Strength in Older Adults With and Without Type 2 Diabetes by Samakkarnthai, Parinya, Sfeir, Jad G, Atkinson, Elizabeth J, Achenbach, Sara J, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Farr, Joshua N, Khosla, Sundeep

“…Patients with Type 2 Diabetes (T2D) are at increased fracture risk despite having relatively normal or even increased BMD by DXA. The critical aspect of bone…”
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SUN-381 Cortical Porosity Is Associated with Peripheral Small Vessel Disease in Adult Patients with Type 2 Diabetes by Samakkarnthai, Parinya, Sfeir, Jad G, Wennberg, Paul W, Dyck, Peter J, Achenbach, Sara J, Atkinson, Elizabeth J, Tweed, Amanda J, Volkman, Tammie L, Drake, Matthew T, Farr, Joshua N, Khosla, Sundeep

“…Patients with Type 2 Diabetes (T2D) are at higher fracture risk despite having relatively normal or even increased BMD by DXA. Increased cortical porosity has…”
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Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney diseaseResearch in context by LaTonya J. Hickson, Larissa G.P. Langhi Prata, Shane A. Bobart, Tamara K. Evans, Nino Giorgadze, Shahrukh K. Hashmi, Sandra M. Herrmann, Michael D. Jensen, Qingyi Jia, Kyra L. Jordan, Todd A. Kellogg, Sundeep Khosla, Daniel M. Koerber, Anthony B. Lagnado, Donna K. Lawson, Nathan K. LeBrasseur, Lilach O. Lerman, Kathleen M. McDonald, Travis J. McKenzie, João F. Passos, Robert J. Pignolo, Tamar Pirtskhalava, Ishran M. Saadiq, Kalli K. Schaefer, Stephen C. Textor, Stella G. Victorelli, Tammie L. Volkman, Ailing Xue, Mark A. Wentworth, Erin O. Wissler Gerdes, Yi Zhu, Tamara Tchkonia, James L. Kirkland

“…Background: Senescent cells, which can release factors that cause inflammation and dysfunction, the senescence-associated secretory phenotype (SASP),…”
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