Search Results - "Tami, J A"

A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis by van Deventer, S J H, Tami, J A, Wedel, M K

“…Objective: To evaluate the safety and efficacy of an enema formulation of alicaforsen, an antisense inhibitor of intercellular adhesion molecule, after 1, 3,…”
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A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease by Yacyshyn, Bruce R., Bowen-Yacyshyn, Mary Beth, Jewell, Lawrence, Tami, Joseph A., Bennett, C.Frank, Kisner, Daniel L., Shanahan, William R.

“…Background & Aims: Intercellular adhesion molecule 1 (ICAM-1) plays an important role in the trafficking and activation of leukocytes and is up-regulated in…”
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Gene polymorphisms and serological markers of patients with active Crohn's disease in a clinical trial of antisense to ICAM‐1 by Yacyshyn, B. R., Schievella, A., Sewell, K. L., Tami, J. A.

“…Summary Serological profiles for anti‐Saccharomyces cerevisiae antibodies (ASCA)/ perinuclear antineutrophil cytoplasmic antibodies (pANCA) and gene…”
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T cell hybridomas reactive with the acetylcholine receptor and its subunits by Tami, JA, Urso, OE, Krolick, KA

“…A panel of thirty cloned rat-mouse T cell hybridomas was prepared by fusion of acetylcholine receptor (AChR)-reactive rat T cells with the mouse thymoma…”
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Immunology for the clinical pharmacist by Tami, J A

“…Major advances in the field of immunology within the past decade have led to greater understanding of the immune network. The immune system is finely balanced,…”
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Procainamide-induced myasthenic crisis by Godley, P J, Morton, T A, Karboski, J A, Tami, J A

“…We describe a case of procainamide-induced respiratory failure in a myasthenic patient with no prior history of respiratory weakness. Respiratory failure was…”
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Recombinant interleukin-2 and the quest for FDA approval by Tami, J A

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Metoclopramide suppository considerations by Tami, J A, Waite, W W

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Monoclonal antibody technology by Tami, J A, Parr, M D, Brown, S A, Thompson, J S

“…The development, production, limitations, and uses of monoclonal antibody (MoAb) technology are presented. The first MoAbs were developed in 1975 using a…”
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The immune system by Tami, J A, Parr, M D, Thompson, J S

“…The components and functions of the immune system are described, and the clinical applications of agents that affect the immune system are discussed. Through…”
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Exacerbated muscle dysfunction by procainamide in rats with experimental myasthenia gravis by Yeh, T M, Tami, J A, Krolick, K A

“…The induction of experimental autoimmune myasthenia gravis (EAMG) has long been shown to result in inefficient function of the acetylcholine receptor (AChR)…”
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Introduction to immunology by McIntyre, W J, Tami, J A

“…The immune system is a complex network of components functioning to provide host defense. This network consists of immunologic cells and their products (e.g.,…”
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Recombinant DNA technology and therapeutics by Tami, J A

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Phase I trial of ISIS 104838, a 2'-methoxyethyl modified antisense oligonucleotide targeting tumor necrosis factor-alpha by Sewell, K Lea, Geary, Richard S, Baker, Brenda F, Glover, Josephine M, Mant, Timothy G K, Yu, Rosie Z, Tami, Joseph A, Dorr, F Andrew

“…ISIS 104838 is a 20-mer phosphorothioate antisense oligonucleotide (ASO) that binds tumor necrosis factor-alpha (TNF-alpha) mRNA. It carries a 2'-methoxyethyl…”
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A randomized, placebo controlled trial of an antisense oligodeoxynucleotide to intercellular adhesion molecule-1 in the treatment of severe rheumatoid arthritis by Walter P Maksymowych, Warren D Blackburn, Jr, Joseph A Tami, William R Shanahan, Jr

“…OBJECTIVE: To determine the safety of an antisense oligodeoxynucleotide to intercellular adhesion molecule-1 (ICAM-1) (ISIS 2302), administered in an intensive…”
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Phase I and phase II safety and efficacy trial of intercellular adhesion molecule-1 antisense oligodeoxynucleotide (ISIS 2302) for the prevention of acute allograft rejection by KAHAN, Barry D, STEPKOWSKI, Stanislaw, KILIC, Murat, KATZ, Steven M, VAN BUREN, Charles T, WELSH, Maria S, TAMI, Joseph A, SHANAHAN, William R

“…ISIS 2302, an antisense oligonucleotide that inhibits the expression of human intercellular adhesion molecule (ICAM)-1, was evaluated in combination with a…”
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Analysis of helper T-cell specificity involved in the antibody response to the acetylcholine receptor by Tami, J A, Krolick, K A

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