Search Results - "Tamgüney, Gültekin"

GI infections are associated with an increased risk of Parkinson's disease by Nerius, Michael, Doblhammer, Gabriele, Tamgüney, Gültekin

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Recurring Gastrointestinal Infections Increase the Risk of Dementia by Fink, Anne, Doblhammer, Gabriele, Tamgüney, Gültekin

“…Gastrointestinal infections cause significant health problems, including those affecting the immune, musculoskeletal, and nervous system, and are one of the…”
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Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats by Van Den Berge, Nathalie, Ferreira, Nelson, Gram, Hjalte, Mikkelsen, Trine Werenberg, Alstrup, Aage Kristian Olsen, Casadei, Nicolas, Tsung-Pin, Pai, Riess, Olaf, Nyengaard, Jens Randel, Tamgüney, Gültekin, Jensen, Poul Henning, Borghammer, Per

“…The conversion of endogenous alpha-synuclein (asyn) to pathological asyn-enriched aggregates is a hallmark of Parkinson’s disease (PD). These inclusions can be…”
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Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats by Van Den Berge, Nathalie, Ferreira, Nelson, Mikkelsen, Trine Werenberg, Alstrup, Aage Kristian Olsen, Tamgüney, Gültekin, Karlsson, Páll, Terkelsen, Astrid Juhl, Nyengaard, Jens Randel, Jensen, Poul Henning, Borghammer, Per

“…Neuronal aggregates of misfolded alpha-synuclein protein are found in the brain and periphery of patients with Parkinson's disease. Braak and colleagues have…”
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Oral and intravenous transmission of α-synuclein fibrils to mice by Lohmann, Stephanie, Bernis, Maria E., Tachu, Babila J., Ziemski, Alexandra, Grigoletto, Jessica, Tamgüney, Gültekin

“…Parkinson’s disease and related disorders are neuropathologically characterized by cellular deposits of misfolded and aggregated α-synuclein in the CNS…”
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A critical review of the prion hypothesis of human synucleinopathies by Tamgüney, Gültekin, Korczyn, Amos D.

“…Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are neurodegenerative disorders which have been pathologically…”
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Utilization of a Branched Late-Stage Clickable Biotinylated Chassis on the Example of a Pittsburgh B Analogue by Weber, T. Moritz, Özdüzenciler, Pelin, Tamgüney, Gültekin, Pietruszka, Jörg

“…Biotinylation is probably the most frequent and practically useful modification of molecules to facilitate selective and highly affine binding to…”
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Transmission of Elk and Deer Prions to Transgenic Mice by TAMGÜNEY, Gültekin, GILES, Kurt, BOUZAMONDO-BERNSTEIN, Essia, BOSQUE, Patrick J, MILLER, Michael W, SAFAR, Jiri, DEARMOND, Stephen J, PRUSINER, Stanley B

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Body-first Parkinson’s disease and variant Creutzfeldt–Jakob disease – similar or different? by Woerman, Amanda L., Tamgüney, Gültekin

“…In several neurodegenerative disorders, proteins that typically exhibit an α-helical structure misfold into an amyloid conformation rich in β-sheet content…”
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Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein by Bernis, Maria E, Babila, Julius T, Breid, Sara, Wüsten, Katharina Annick, Wüllner, Ullrich, Tamgüney, Gültekin

“…Parkinson's disease (PD) and multiple system atrophy (MSA) are neurodegenerative diseases that are characterized by the intracellular accumulation of…”
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Colonoscopy and Subsequent Risk of Parkinson’s Disease by Holtz, Anna-Victoria, Fink, Anne, Tamgüney, Gültekin, Doblhammer, Gabriele

“…Background: Parkinson’s disease (PD) is caused by the misfolding and aggregation of α-synuclein in neurons into toxic oligomers and fibrils that have…”
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Asymptomatic deer excrete infectious prions in faeces by Miller, Michael W, Tamgüney, Gültekin, Wolfe, Lisa L, Palmer, Christina, DeArmond, Stephen J, Sirochman, Tracey M, Lemus, Azucena, Glidden, David V, Prusiner, Stanley B

“…Infectious prion diseases-scrapie of sheep and chronic wasting disease (CWD) of several species in the deer family-are transmitted naturally within affected…”
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A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization by Wüsten, Katharina Annick, Reddy, Pasham Parameshwar, Smiyakin, Andrej, Bernis, Maria Eugenia, Tamgüney, Gültekin

“…The prion protein (PrP) is a cell surface protein that in disease misfolds and becomes infectious causing Creutzfeldt-Jakob disease in humans, scrapie in…”
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Elevated Aβ aggregates in feces from Alzheimer's disease patients: a proof-of-concept study by Pils, Marlene, Dybala, Alexandra, Schaffrath, Anja, Rehn, Fabian, Kutzsche, Janine, Blömeke, Lara, Tusche, Markus, Özdüzenciler, Pelin, Bujnicki, Tuyen, Kraemer-Schulien, Victoria, Gramespacher, Hannes, Schmieschek, Maximilian H T, Barbe, Michael T, Onur, Oezguer A, Fink, Gereon R, Tamgüney, Gültekin, Bannach, Oliver, Willbold, Dieter

“…Misfolding and aggregation of amyloid β (Aβ), along with neurofibrillary tangles consisting of aggregated Tau species, are pathological hallmarks of…”
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Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool by Schaffrath, Anja, Schleyken, Sophia, Seger, Aline, Jergas, Hannah, Özdüzenciler, Pelin, Pils, Marlene, Blömeke, Lara, Cousin, Anneliese, Willbold, Johannes, Bujnicki, Tuyen, Bannach, Oliver, Fink, Gereon R., Willbold, Dieter, Sommerauer, Michael, Barbe, Michael T., Tamgüney, Gültekin

“…Misfolded and aggregated α-synuclein is a neuropathological hallmark of Parkinson’s disease (PD). Thus, α-synuclein aggregates are regarded as a biomarker for…”
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Ligand-Induced Stabilization of the Native Human Superoxide Dismutase 1 by Santur, Karoline, Reinartz, Elke, Lien, Yi, Tusche, Markus, Altendorf, Tim, Sevenich, Marc, Tamgüney, Gültekin, Mohrlüder, Jeannine, Willbold, Dieter

“…A common characteristic of familial (fALS) and sporadic amyotrophic lateral sclerosis (sALS) is the accumulation of aberrant proteinaceous species in the motor…”
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Stabilization of Monomeric Tau Protein by All D-Enantiomeric Peptide Ligands as Therapeutic Strategy for Alzheimer's Disease and Other Tauopathies by Altendorf, Tim, Gering, Ian, Santiago-Schübel, Beatrix, Aghabashlou Saisan, Selma, Tamgüney, Gültekin, Tusche, Markus, Honold, Dominik, Schemmert, Sarah, Hoyer, Wolfgang, Mohrlüder, Jeannine, Willbold, Dieter

“…Alzheimer's disease and other tauopathies are the world's leading causes of dementia and memory loss. These diseases are thought to be caused by the misfolding…”
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Ischemic stroke causes Parkinson's disease-like pathology and symptoms in transgenic mice overexpressing alpha-synuclein by Lohmann, Stephanie, Grigoletto, Jessica, Bernis, Maria Eugenia, Pesch, Verena, Ma, Liang, Reithofer, Sara, Tamgüney, Gültekin

“…The etiology of Parkinson's disease is poorly understood and is most commonly associated with advancing age, genetic predisposition, or environmental toxins…”
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Rational design of structure‐based vaccines targeting misfolded alpha‐synuclein conformers of Parkinson's disease and related disorders by Flores‐Fernandez, Jose Miguel, Pesch, Verena, Sriraman, Aishwarya, Chimal‐Juarez, Enrique, Amidian, Sara, Wang, Xiongyao, Duckering, Caleb, Fang, Andrew, Reithofer, Sara, Ma, Liang, Cortez, Leonardo M., Sim, Valerie L., Tamgüney, Gültekin, Wille, Holger

“…Synucleinopathies, including Parkinson's disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), are neurodegenerative disorders…”
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Chimeric elk/mouse prion proteins in transgenic mice by Tamgüney, Gültekin, Giles, Kurt, Oehler, Abby, Johnson, Natrina L, DeArmond, Stephen J, Prusiner, Stanley B

“…Chronic wasting disease (CWD) of deer and elk is a highly communicable neurodegenerative disorder caused by prions. Investigations of CWD are hampered by slow…”
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