Search Results - "Tambutet, Guillaume"

Dual-Face Nucleoside Scaffold Featuring a Stereogenic All-Carbon Quaternary Center. Intramolecular Silicon Tethered Group-Transfer Reaction by Tambutet, Guillaume, Becerril-Jiménez, Fabiola, Dostie, Starr, Simard, Ryan, Prévost, Michel, Mochirian, Philippe, Guindon, Yvan

“…The design of a novel nucleoside scaffold that exhibits an all-carbon quaternary center is reported. This allows for both α- and β-anomers of a given…”
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Diastereoselective Radical Hydrogen Transfer Reactions using N‑Heterocyclic Carbene Boranes by Tambutet, Guillaume, Guindon, Yvan

“…Reported herein are the first diastereoselective and Lewis acid-mediated radical reactions of N-heterocyclic carbene (NHC) boranes. We applied these reactions…”
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Diastereoselective Synthesis of C2′-Fluorinated Nucleoside Analogues Using an Acyclic Approach by Dostie, Starr, Prévost, Michel, Mochirian, Philippe, Tanveer, Kashif, Andrella, Nicholas, Rostami, Ariana, Tambutet, Guillaume, Guindon, Yvan

“…Nucleoside analogues bearing a fluorine in the C2′-position have been synthesized by SN2-like cyclizations of acyclic thioaminal precursors. This strategy…”
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Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen by Pelletier, Benoit, Duhamel, Stéphanie, Tambutet, Guillaume, Jarvis, Scott, Cléroux, Patrick, David, Maud, Tanguay, Pierre-Luc, Voisin, Laure, James, Clint, Lavoie, Rico, Gareau, Yves, Flynn-Robitaille, Joël, Lorca, Thierry, Ruel, Réjean, Marinier, Anne, Meloche, Sylvain

“…p21Cip1 (p21) is a universal cyclin-dependent kinase (CDK) inhibitor that halts cell proliferation and tumor growth by multiple mechanisms. The expression of…”
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Synthesis of Thieno[3,2-e][1,4]diazepin-2-ones: Application of an Uncatalysed Pictet-Spengler Reaction by Denoyelle, Séverine, Tambutet, Guillaume, Masurier, Nicolas, Maillard, Ludovic T., Martinez, Jean, Lisowski, Vincent

“…A series of 5‐substituted thieno[3,2‐e][1,4]diazepin‐2‐ones was synthesized in four steps from methyl 3‐aminothiophene‐2‐carboxylate. After the coupling of…”
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Acyclic Tethers Mimicking Subunits of Polysaccharide Ligands: Selectin Antagonists by Calosso, Mickael, Tambutet, Guillaume, Charpentier, Daniel, St-Pierre, Gabrielle, Vaillancourt, Marc, Bencheqroun, Mohammed, Gratton, Jean-Philippe, Prévost, Michel, Guindon, Yvan

“…We report on the design and synthesis of molecules having E- and P-selectins blocking activity both in vitro and in vivo. The GlcNAc component of the selectin…”
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