Search Results - "Tambourgi, Denise V."

Toxicon and Toxicon: X – 2022 and beyond by Norton, Raymond S., Tambourgi, Denise V.

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Complement System Inhibitory Drugs in a Zebrafish (Danio rerio) Model: Computational Modeling by Fernandes, Dayanne Carla, Tambourgi, Denise V

“…The dysregulation of complement system activation usually results in acute or chronic inflammation and can contribute to the development of various diseases…”
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Ordered Mesoporous Silica SBA-15: A New Effective Adjuvant to Induce Antibody Response by Mercuri, Lucildes P., Carvalho, Luciana V., Lima, Flávia A., Quayle, Carolina, Fantini, Márcia C. A., Tanaka, Gabriela S., Cabrera, Wafa H., Furtado, Maria F. D., Tambourgi, Denise V., Matos, Jivaldo do R., Jaroniec, Mietek, Sant'Anna, Osvaldo A.

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IgY: A promising antibody for use in immunodiagnostic and in immunotherapy by Dias da Silva, Wilmar, Tambourgi, Denise V.

“…Immunoglobulin IgY is the major antibody produced by chickens ( Gallus domesticus). After their V-C gene is rearranged in B cells, IgY is continually…”
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Hyaluronan breakdown by snake venom hyaluronidases: From toxins delivery to immunopathology by Silva de França, Felipe, Tambourgi, Denise V

“…Snake venom enzymes have a broad range of molecular targets in plasma, tissues, and cells, among which hyaluronan (HA) is outstanding. HA is encountered in the…”
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Editorial: Immune responses and immune mechanisms triggered by snake and scorpion venoms by Pucca, Manuela B., Tambourgi, Denise V., Monteiro, Wuelton M.

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Complement System Inhibition Modulates the Inflammation Induced by the Venom of Premolis semirufa, an Amazon Rainforest Moth Caterpillar by Gabrili, Joel J. M., Villas-Boas, Isadora Maria, Pidde, Giselle, Squaiella-Baptistão, Carla Cristina, Woodruff, Trent M., Tambourgi, Denise V.

“…The caterpillar of the Premolis semirufa moth, commonly called Pararama, is found in the Brazilian Amazon region. Contact with the hairs can cause a chronic…”
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Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the C5a receptor by van den Berg, Carmen W, Tambourgi, Denise V, Clark, Howard W, Hoong, S Julie, Spiller, O Brad, McGreal, Eamon P

“…Neutrophil dysfunction, resulting in inefficient bacterial clearance, is a feature of several serious medical conditions, including cystic fibrosis (CF) and…”
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New Insights into Immunopathology Associated to Bothrops lanceolatus Snake Envenomation: Focus on PLA2 Toxin by Gabrili, Joel J. M., Pidde, Giselle, Magnoli, Fabio Carlos, Marques-Porto, Rafael, Villas-Boas, Isadora Maria, Squaiella-Baptistão, Carla Cristina, Silva-de-França, Felipe, Burgher, François, Blomet, Joël, Tambourgi, Denise V.

“…The systemic increase in inflammatory mediator levels can induce diverse pathological disorders, including potentially thrombus formation, which may be lethal…”
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Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem by Hui Wen, Fan, Monteiro, Wuelton Marcelo, Moura da Silva, Ana Maria, Tambourgi, Denise V, Mendonça da Silva, Iran, Sampaio, Vanderson S, dos Santos, Maria Cristina, Sachett, Jacqueline, Ferreira, Luiz Carlos L, Kalil, Jorge, Lacerda, Marcus

“…  Field work is not limited to animal collection; it also includes studies of behavioral patterns such as diet, reproduction, and activities to establish…”
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Bothrops jararaca Snake Venom Inflammation Induced in Human Whole Blood: Role of the Complement System by Leonel, Thyago Bispo, Gabrili, Joel José Megale, Squaiella-Baptistão, Carla Cristina, Woodruff, Trent M, Lambris, John D, Tambourgi, Denise V

“…The clinical manifestations of envenomation by species are complex and characterized by prominent local effects that can progress to tissue loss, physical…”
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Complement System Inhibition Modulates the Pro-Inflammatory Effects of a Snake Venom Metalloproteinase by Luchini, Lygia Samartin Gonçalves, Pidde, Giselle, Squaiella-Baptistão, Carla Cristina, Tambourgi, Denise V

“…Envenomation by snakes causes prominent local effects, including pain, oedema, local bleeding, blistering and necrosis, and systemic manifestations, such as…”
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Sphingomyelinases D From Loxosceles Spider Venoms and Cell Membranes: Action on Lipid Rafts and Activation of Endogenous Metalloproteinases by Lopes, Priscila Hess, van den Berg, Carmen W, Tambourgi, Denise V

“…spider venom contains Sphingomyelinase D (SMase D), the key toxin causing pathology. SMase D hydrolyzes the main component of lipid rafts, sphingomyelin, which…”
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C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera by Silva de França, Felipe, Villas-Boas, Isadora Maria, Cogliati, Bruno, Woodruff, Trent M, Reis, Edimara da Silva, Lambris, John D, Tambourgi, Denise V

“…Systemic complement activation drives a plethora of pathological conditions, but its role in snake envenoming remains obscure. Here, we explored complement's…”
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Oral Tolerance Induction by Bothrops jararaca Venom in a Murine Model and Cross-Reactivity with Toxins of Other Snake Venoms by Tsuruta, Lilian Rumi, Moro, Ana Maria, Tambourgi, Denise V, Sant'Anna, Osvaldo Augusto

“…Oral tolerance is defined as a specific suppression of cellular and humoral immune responses to a particular antigen through prior oral administration of an…”
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Sphingomyelinase D Activity in Sicarius tropicus Venom: Toxic Potential and Clues to the Evolution of SMases D in the Sicariidae Family by Lopes, Priscila Hess, Fukushima, Caroline Sayuri, Shoji, Rosana, Bertani, Rogério, Tambourgi, Denise V

“…The spider family Sicariidae includes three genera, , and . The three genera share a common characteristic in their venoms: the presence of Sphingomyelinases D…”
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Naja annulifera Snake: New insights into the venom components and pathogenesis of envenomation by Silva-de-França, Felipe, Villas-Boas, Isadora Maria, Serrano, Solange Maria de Toledo, Cogliati, Bruno, Chudzinski, Sonia Aparecida de Andrade, Lopes, Priscila Hess, Kitano, Eduardo Shigueo, Okamoto, Cinthya Kimori, Tambourgi, Denise V

“…Naja annulifera is a medically important venomous snake occurring in some of the countries in Sub-Saharan Africa. Accidental bites result in severe coagulation…”
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Toxicon and Toxicon: X – 2022 and beyond by Norton, Raymond S., Tambourgi, Denise V.

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Enzymatic and Pro-Inflammatory Activities of Bothrops lanceolatus Venom: Relevance for Envenomation by Delafontaine, Marie, Villas-Boas, Isadora Maria, Mathieu, Laurence, Josset, Patrice, Blomet, Joël, Tambourgi, Denise V

“…, commonly named 'Fer-de-Lance', is an endemic snake of the French Caribbean Island of Martinique. Envenomations by present clinical aspects characterized by…”
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Integrative multiomics analysis of Premolis semirufa caterpillar venom in the search for molecules leading to a joint disease by Pidde, Giselle, Nishiyama, Milton Y., de Oliveira, Ursula Castro, Villas-Boas, Isadora M., Paes-Leme, Adriana F., Junqueira-de-Azevedo, Inácio L., Marques-Porto, Rafael, Squaiella-Baptistão, Carla C., Tambourgi, Denise V.

“…The joint disease called pararamosis is an occupational disease caused by accidental contact with bristles of the caterpillar Premolis semirufa . The chronic…”
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