Search Results - "Tamborero, D"

Genomic testing for targeted oncology drugs: hopes against hype by Dienstmann, R., Tamborero, D.

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Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets by Karube, K, Enjuanes, A, Dlouhy, I, Jares, P, Martin-Garcia, D, Nadeu, F, Ordóñez, G R, Rovira, J, Clot, G, Royo, C, Navarro, A, Gonzalez-Farre, B, Vaghefi, A, Castellano, G, Rubio-Perez, C, Tamborero, D, Briones, J, Salar, A, Sancho, J M, Mercadal, S, Gonzalez-Barca, E, Escoda, L, Miyoshi, H, Ohshima, K, Miyawaki, K, Kato, K, Akashi, K, Mozos, A, Colomo, L, Alcoceba, M, Valera, A, Carrió, A, Costa, D, Lopez-Bigas, N, Schmitz, R, Staudt, L M, Salaverria, I, López-Guillermo, A, Campo, E

“…Genome studies of diffuse large B-cell lymphoma (DLBCL) have revealed a large number of somatic mutations and structural alterations. However, the clinical…”
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Pre-procedural predictors of atrial fibrillation recurrence after circumferential pulmonary vein ablation by Berruezo, Antonio, Tamborero, David, Mont, Lluis, Benito, Begoña, Tolosana, Jose María, Sitges, Marta, Vidal, Bárbara, Arriagada, Germán, Méndez, Francisco, Matiello, Maria, Molina, Irma, Brugada, Josep

“…Aims The success rate of circumferential pulmonary vein ablation (CPVA) to treat atrial fibrillation (AF) ranges from 60 to 90%, depending on the series. The…”
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Low efficacy of atrial fibrillation ablation in severe obstructive sleep apnoea patients by Matiello, Maria, Nadal, Mercé, Tamborero, David, Berruezo, Antonio, Montserrat, Josep, Embid, Cristina, Rios, Jose, Villacastín, Julián, Brugada, Josep, Mont, Lluís

“…Atrial fibrillation (AF) ablation efficacy varies according to patients' clinical characteristics. Although the association of obstructive sleep apnoea (OSA)…”
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Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia by Ojamies, P N, Kontro, M, Edgren, H, Ellonen, P, Lagström, S, Almusa, H, Miettinen, T, Eldfors, S, Tamborero, D, Wennerberg, K, Heckman, C, Porkka, K, Wolf, M, Kallioniemi, O

“…In our individualized systems medicine program, personalized treatment options are identified and administered to chemorefractory acute myeloid leukemia (AML)…”
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Efficacy of circumferential pulmonary vein ablation of atrial fibrillation in endurance athletes by Calvo, Naiara, Mont, Lluís, Tamborero, David, Berruezo, Antonio, Viola, Graziana, Guasch, Eduard, Nadal, Mercè, Andreu, David, Vidal, Barbara, Sitges, Marta, Brugada, Josep

“…Aims Long-term endurance sport practice has been increasingly recognized as a risk factor for lone atrial fibrillation (AF). However, data on the outcome of…”
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455: The role of new cancer hallmarks in tumorigenesis by Gonzalez-Perez, A, Jene-Sanz, A, Tamborero, D, Lopez-Bigas, N

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Usefulness of transoesophageal echocardiography before circumferential pulmonary vein ablation in patients with atrial fibrillation: is it really mandatory? by Calvo, N, Mont, L, Vidal, B, Nadal, M, Montserrat, S, Andreu, D, Tamborero, D, Pare, C, Azqueta, M, Berruezo, A, Brugada, J, Sitges, M

“…Transoesophageal echocardiography (TEE) is recommended prior to circumferential pulmonary vein ablation (CPVA) in patients with atrial fibrillation (AF) to…”
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46: Proffered Paper: Therapeutical landscape of cancer drivers by Gonzalez-Perez, A, Tamborero, D, Rubio, C, Schroeder, M, Perez-Llamas, C, Deu-Pons, J, Lopez-Bigas, N

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Mutational and Clonal Dynamics During Progression from MDS to SAML by Whole-Exome and Targeted-Deep Sequencing by Martín Izquierdo, M, Abáigar, M, Hernández-Sánchez, J.M, Tamborero, D, Díez-Campelo, M, Hernández-Sánchez, M, Ramos, F, Megido, M, Aguilar, C, Lumbreras, E, Redondo-Guijo, A, Recio, I, Olivier, C, Benito, R, López-Bigas, N, del Cañizo, M.C, Hernández-Rivas, J.M

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Identification of precision treatment strategies for high risk multiple myeloma by ex vivo drug sensitivity testing by Majumder, M.M, Silvennoinen, R, Anttila, P, Tamborero, D, Eldfors, S, Karjalainen, R, Kuusanmäki, H, Lievonen, J, Parsons, A, Suvela, M, Porkka, K, Heckman, C

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Characterization of focal right atrial appendage tachycardia by Freixa, Xavier, Berruezo, Antonio, Mont, Lluís, Magnani, Santiago, Benito, Begoña, Tolosana, Jose María, Perafan, Pablo, Tamborero, David, Brugada, Josep

“…Aims Though right atrial appendage tachycardia (RAAT) has been described, no studies to date have focused on its clinical characterization. The aim of the…”
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Quantification of Left Ventricular Asynchrony Throughout the Whole Cardiac Cycle with a Computed Algorithm: Application for Optimizing Resynchronization Therapy by SILVA, E., SITGES, M., MONT, L., DELGADO, V., TAMBORERO, D., VIDAL, B., GODOY, M., POYATOS, S., PARE, C., AZQUETA, M., BRUGADA, J.

“…Introduction: Measurement of left ventricular (LV) asynchrony is usually determined on single time points from spectral tissue Doppler imaging (TDI) scans that…”
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Six-minute walking test predicts long-term cardiac death in patients who received cardiac resynchronization therapy by Castel, María Ángeles, Méndez, Francisco, Tamborero, David, Mont, Lluís, Magnani, Santiago, Tolosana, Jose Maria, Berruezo, Antonio, Godoy, Miguel, Sitges, Marta, Vidal, Barbara, Roig, Eulàlia, Brugada, Josep

“…Aims Cardiac resynchronization therapy (CRT) has been proven to be effective in patients suffering from chronic heart failure (CHF) associated with electrical…”
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NK Cell Infiltrates and HLA Class I Expression in Primary HER2 + Breast Cancer Predict and Uncouple Pathological Response and Disease-free Survival by Muntasell, Aura, Rojo, Federico, Servitja, Sonia, Rubio-Perez, Carlota, Cabo, Mariona, Tamborero, David, Costa-García, Marcel, Martínez-Garcia, María, Menéndez, Sílvia, Vazquez, Ivonne, Lluch, Ana, Gonzalez-Perez, Abel, Rovira, Ana, López-Botet, Miguel, Albanell, Joan

“…We investigated the value of tumor-infiltrating NK (TI-NK) cells and HLA class I tumor expression as biomarkers of response to neoadjuvant anti-HER2…”
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A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer by Wagner, Alex H., Walsh, Brian, Mayfield, Georgia, Tamborero, David, Sonkin, Dmitriy, Krysiak, Kilannin, Deu-Pons, Jordi, Duren, Ryan P., Gao, Jianjiong, McMurry, Julie, Patterson, Sara, del Vecchio Fitz, Catherine, Pitel, Beth A., Sezerman, Ozman U., Ellrott, Kyle, Warner, Jeremy L., Rieke, Damian T., Aittokallio, Tero, Cerami, Ethan, Ritter, Deborah I., Schriml, Lynn M., Freimuth, Robert R., Haendel, Melissa, Raca, Gordana, Madhavan, Subha, Baudis, Michael, Beckmann, Jacques S., Dienstmann, Rodrigo, Chakravarty, Debyani, Li, Xuan Shirley, Mockus, Susan, Elemento, Olivier, Schultz, Nikolaus, Lopez-Bigas, Nuria, Lawler, Mark, Goecks, Jeremy, Griffith, Malachi, Griffith, Obi L., Margolin, Adam A.

“…Precision oncology relies on accurate discovery and interpretation of genomic variants, enabling individualized diagnosis, prognosis and therapy selection. We…”
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Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC) by Horak, Peter, Griffith, Malachi, Danos, Arpad M., Pitel, Beth A., Madhavan, Subha, Liu, Xuelu, Chow, Cynthia, Williams, Heather, Carmody, Leigh, Barrow-Laing, Lisa, Rieke, Damian, Kreutzfeldt, Simon, Stenzinger, Albrecht, Tamborero, David, Benary, Manuela, Rajagopal, Padma Sheila, Ida, Cristiane M., Lesmana, Harry, Satgunaseelan, Laveniya, Merker, Jason D., Tolstorukov, Michael Y., Campregher, Paulo Vidal, Warner, Jeremy L., Rao, Shruti, Natesan, Maya, Shen, Haolin, Venstrom, Jeffrey, Roy, Somak, Tao, Kayoko, Kanagal-Shamanna, Rashmi, Xu, Xinjie, Ritter, Deborah I., Pagel, Kym, Krysiak, Kilannin, Dubuc, Adrian, Akkari, Yassmine M., Li, Xuan Shirley, Lee, Jennifer, King, Ian, Raca, Gordana, Wagner, Alex H., Li, Marylin M., Plon, Sharon E., Kulkarni, Shashikant, Griffith, Obi L., Chakravarty, Debyani, Sonkin, Dmitriy

“…Several professional societies have published guidelines for the clinical interpretation of somatic variants, which specifically address diagnostic,…”
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Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal by Tamborero, David, Dienstmann, Rodrigo, Rachid, Maan Haj, Boekel, Jorrit, Baird, Richard, Braña, Irene, De Petris, Luigi, Yachnin, Jeffrey, Massard, Christophe, Opdam, Frans L., Schlenk, Richard, Vernieri, Claudio, Garralda, Elena, Masucci, Michele, Villalobos, Xenia, Chavarria, Elena, Calvo, Fabien, Fröhling, Stefan, Eggermont, Alexander, Apolone, Giovanni, Voest, Emile E., Caldas, Carlos, Tabernero, Josep, Ernberg, Ingemar, Rodon, Jordi, Lehtiö, Janne

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JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML by Karjalainen, Riikka, Pemovska, Tea, Popa, Mihaela, Liu, Minxia, Javarappa, Komal K., Majumder, Muntasir M., Yadav, Bhagwan, Tamborero, David, Tang, Jing, Bychkov, Dmitrii, Kontro, Mika, Parsons, Alun, Suvela, Minna, Mayoral Safont, Mireia, Porkka, Kimmo, Aittokallio, Tero, Kallioniemi, Olli, McCormack, Emmet, Gjertsen, Bjørn T., Wennerberg, Krister, Knowles, Jonathan, Heckman, Caroline A.

“…The bone marrow (BM) provides a protective microenvironment to support the survival of leukemic cells and influence their response to therapeutic agents. In…”
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High‐throughput molecular assays for inclusion in personalised oncology trials – State‐of‐the‐art and beyond by Edsjö, Anders, Russnes, Hege G., Lehtiö, Janne, Tamborero, David, Hovig, Eivind, Stenzinger, Albrecht, Rosenquist, Richard, Janowska, Agnieszka, Rioja, Alba López, Stenzinger, Albrecht, Razzak, Ali, Edsjö, Anders, Lepland, Anni, Marra, Antonio, Planken, Anu, Helland, Åslaug, Patocs, Attila, Mainoli, Beatrice, Ryll, Bettina, Brasiuniene, Birute, Kazdal, Daniel, Tamborero, David, Cerina, Dora, Hult, Ebba Hallersjö, Baltruškevičienė, Edita, Vrdoljak, Eduard, Hovig, Eivind, Chavarria, Elena, Garralda, Elena, Aas, Eline, Bjørgo, Elisa, Voest, Emile, Curigliano, Giuseppe, Fagereng, Gro Live, Gelderblom, Hans, Russnes, Hege G., Verheul, Henk, Timmer, Hans, Brana, Irene, Lugowska, Iwona, Lehtiö, Janne, Blay, Jean‐Yves, Oliveira, Julio, Rekker, Kadri, Toome, Kadri, Jalkanen, Katriina, Taskén, Kjetil, Smeland, Knut, Ojamaa, Kristiina, Rohrberg, Kristoffer Staal, Verlingue, Loic, Antouly, Manon, Mustonen, Mika, Zagami, Paola, Nagy, Péter, Nygren, Peter, Asplund, Peter, Sabaliauskaite, Rasa, Rosenquist, Richard, Henrique, Rui, Waalwijk van Doorn‐Khosrovani, Sahar Barjesteh, Brabrand, Sigmund, Ekman, Simon, Mohammad, Soemeya Haj, Jarmalaite, Sonata, Juslin, Tanja, Kahre, Tiina, Kringelbach, Tina, Guren, Tormod, Lassen, Ulrik, Grolmusz, Vince Kornél, Alberu, Xenia Villabour

“…In the last decades, the development of high‐throughput molecular assays has revolutionised cancer diagnostics, paving the way for the concept of personalised…”
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