Search Results - "Tamblyn, A."

Vitamin D and miscarriage: a systematic review and meta-analysis by Tamblyn, Jennifer A., Pilarski, Nicole S.P., Markland, Alexandra D., Marson, Ella J., Devall, Adam, Hewison, Martin, Morris, Rachel K., Coomarasamy, Arri

“…To investigate whether a significant association between vitamin D status and the risk of miscarriage or recurrent miscarriage (RM) exists. Systematic review…”
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Trophoblast uptake of DBP regulates intracellular actin and promotes matrix invasion by Ganguly, Ankana, Tamblyn, Jennifer A, Shattock, Alexandra, Joseph, Annsha, Larner, Dean P, Jenkinson, Carl, Gupta, Janesh, Gross, Stephane R, Hewison, Martin

“…Early pregnancy is characterised by elevated circulating levels of vitamin D binding protein (DBP). The impact of this on maternal and fetal health is unclear…”
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The immunological basis of villitis of unknown etiology – Review by Tamblyn, J.A, Lissauer, D.M, Powell, R, Cox, P, Kilby, M.D

“…Abstract Villitis of unknown etiology (VUE) represents a common placental inflammatory lesion, primarily, but not exclusively, identifiable T lymphocytes at…”
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Vitamin D Promotes Trophoblast Cell Induced Separation of Vascular Smooth Muscle Cells in Vascular Remodeling via Induction of G-CSF by Zhang, Joy Yue, Wu, Peihuang, Chen, Danyang, Ning, Fen, Lu, Qinsheng, Qiu, Xiu, Hewison, Martin, Tamblyn, Jennifer A, Kilby, Mark D, Lash, Gendie E

“…Vitamin D deficiency is associated with complications of pregnancy such as pre-eclampsia, fetal growth restriction, and miscarriage, all of which are also…”
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Serum and urine vitamin D metabolite analysis in early preeclampsia by Tamblyn, J A, Jenkinson, C, Larner, D P, Hewison, M, Kilby, M D

“…Vitamin D deficiency is common in pregnant women and may contribute to adverse events in pregnancy such as preeclampsia (PET). To date, studies of vitamin D…”
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Transcriptomic analysis of vitamin D responses in uterine and peripheral NK cells by Tamblyn, J A, Jeffery, L E, Susarla, R, Lissauer, D M, Coort, S L, Garcia, A Muñoz, Knoblich, K, Fletcher, A L, Bulmer, J N, Kilby, M D, Hewison, M

“…Vitamin D deficiency is prevalent in pregnant women and is associated with adverse pregnancy outcomes, in particular disorders of malplacentation. The active…”
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Defining vitamin D status using multi-metabolite mathematical modelling: A pregnancy perspective by Beentjes, C.H.L., Taylor-King, J.P., Bayani, A., Davis, C.N., Dunster, J.L., Jabbari, S., Mirams, G.R., Jenkinson, C., Kilby, M.D., Hewison, M., Tamblyn, J.A.

“…•Measurement of a single serum vitamin D metabolite provides only a limit perspective on vitamin D function.•Multiple vitamin D metabolites may contribute to…”
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Immunological role of vitamin D at the maternal–fetal interface by Tamblyn, J A, Hewison, M, Wagner, C L, Bulmer, J N, Kilby, M D

“…During pregnancy, immune activity is tightly regulated so that antimicrobial protection of the mother and fetus is balanced with the need for immune tolerance…”
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Vitamin D, the placenta and early pregnancy: effects on trophoblast function by Ganguly, Ankana, Tamblyn, Jennifer A, Finn-Sell, Sarah, Chan, Shiao-Y, Westwood, Melissa, Gupta, Janesh, Kilby, Mark D, Gross, Stephane R, Hewison, Martin

“…Pregnancy is associated with significant changes in vitamin D metabolism, notably increased maternal serum levels of active vitamin D, 1,25-dihydroxyvitamin…”
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Management of obstetric postpartum hemorrhage: a national service evaluation of current practice in the UK by Al Wattar, Bassel H, Tamblyn, Jennifer A, Parry-Smith, William, Prior, Mathew, Van Der Nelson, Helen

“…Postpartum hemorrhage (PPH) continues to be one of the major causes of maternal mortality and morbidity in obstetrics. Variations in practice often lead to…”
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11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool by Barnard, Lise, Schiffer, Lina, Louw du-Toit, Renate, Tamblyn, Jennifer A, Chen, Shiuan, Africander, Donita, Arlt, Wiebke, Foster, Paul A, Storbeck, Karl-Heinz

“…Androgens are the obligatory precursors of estrogens. In humans, classic androgen biosynthesis yields testosterone, thought to represent the predominant…”
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Dysregulation of maternal and placental vitamin D metabolism in preeclampsia by Tamblyn, J.A, Susarla, R, Jenkinson, C, Jeffery, L.E, Ohizua, O, Chun, R.F, Chan, S.Y, Kilby, M.D, Hewison, M

“…Abstract Introduction Epidemiology has linked preeclampsia (PET) to decreased maternal serum 25-hydroxyvitamin D3 (25(OH)D3). However, alterations in systemic…”
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Vitamin D-deficiency and sex-specific dysregulation of placental inflammation by Liu, Nancy Q., Larner, Dean P., Yao, Qingqiang, Chun, Rene F., Ouyang, Yuxin, Zhou, Rui, Tamblyn, Jennifer A., Wagner, Carol L., Hewison, Martin

“…•Immune challenge during murine pregnancy increases serum inflammatory markers.•Vitamin D-deficiency exacerbates pregnancy inflammation.•Maternal inflammation…”
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Prenatal therapy in transient abnormal myelopoiesis: a systematic review by Tamblyn, J A, Norton, A, Spurgeon, L, Donovan, V, Bedford Russell, A, Bonnici, J, Perkins, K, Vyas, P, Roberts, I, Kilby, M D

“…To systematically review current evidence regarding prenatal diagnosis and management of transient abnormal myelopoiesis (TAM) in fetuses with trisomy 21. A…”
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Detectable Circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA in Non-Oropharyngeal Head and Neck Cancers by Duffy, E.W., Kaczmar, J., Albergotti, W., Kejner, A., Newman, J.G., Graboyes, E.M., Tamblyn, A., Chera, B.S.

“…Plasma ctHPVDNA is detectable prior to treatment in ∼90% of patients with HPV-OPSCC and has shown utility in the dynamic monitoring of treatment response and…”
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The role of ultrasound in fetal congenital myopathy detection: a novel case of fetal-onset cap myopathy by Tamblyn, J. A., Morris, R. K., Cox, P., Hargitai, B., Kilby, M. D.

“…What's already known about this topic? Rare heterogeneous group of neuromuscular disorders. Associated with severe, often fatal phenotypes – Prenatal parental…”
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Multiple Representations Using Dynamic Geometry by Tamblyn, Michael A., Lynch-Davis, Kathleen, Espy, Tracy Goodson

“…The power of The Geometer's Sketchpad (GSP) for teaching and learning lies in its potential for enabling students to explore geometric concepts and recognize…”
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11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool by Barnard, Lise, Schiffer, Lina, Louw du-Toit, Renate, Tamblyn, Jennifer A, Chen, Shiuan, Africander, Donita, Arlt, Wiebke, Foster, Paul A, Storbeck, Karl-Heinz

“…Androgens are the obligatory precursors of estrogens. In humans, classic androgen biosynthesis yields testosterone, thought to represent the predominant…”
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11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool by Barnard, Lise, Schiffer, Lina, Louw du-Toit, Renate, Tamblyn, Jennifer A, Chen, Shiuan, Africander, Donita, Arlt, Wiebke, Foster, Paul A, Storbeck, Karl-Heinz

“…Androgens are the obligatory precursors of estrogens. In humans, classic androgen biosynthesis yields testosterone, thought to represent the predominant…”
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Clopidogrel induced suppression of bovine platelet activation in vitro and a preliminary study of its effect on the development of Mannheimia haemolytica induced pneumonia by Coomber, Brenda L., Mitchell, Gordon B., Starr, Amanda E., Minhas, Kanwal, Tamblyn, Angela, Shewen, Patricia E., Gentry, Patricia A.

“…We report here on the influence of the platelet antagonist clopidogrel (Plavix) on bovine platelet function. We first evaluated the capacity of clopidogrel to…”
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