Search Results - "Tamashiro, Kellie L."
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Chronic Corticosterone Exposure Increases Expression and Decreases Deoxyribonucleic Acid Methylation of Fkbp5 in Mice
Published in Endocrinology (Philadelphia) (01-09-2010)“…There is evidence for hypercortisolemia playing a role in the generation of psychiatric symptoms and for epigenetic variation within…”
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Maternal High-Fat Diet During Gestation or Suckling Differentially Affects Offspring Leptin Sensitivity and Obesity
Published in Diabetes (New York, N.Y.) (01-11-2012)“…Maternal high-fat (HF) diet throughout gestation and suckling has long-term consequences on the offspring's metabolic phenotype. Here we determine the relative…”
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Maternal stress and high-fat diet effect on maternal behavior, milk composition, and pup ingestive behavior
Published in Physiology & behavior (01-09-2011)“…Abstract Chronic variable prenatal stress or maternal high-fat diet results in offspring that are significantly heavier by the end of the first postnatal week…”
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Role of miR-181c in Diet-induced obesity through regulation of lipid synthesis in liver
Published in PloS one (08-12-2021)“…We recently identified a nuclear-encoded miRNA (miR-181c) in cardiomyocytes that can translocate into mitochondria to regulate mitochondrial gene mt-COX1 and…”
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Prenatal Stress or High-Fat Diet Increases Susceptibility to Diet-Induced Obesity in Rat Offspring
Published in Diabetes (New York, N.Y.) (01-05-2009)“…Prenatal Stress or High-Fat Diet Increases Susceptibility to Diet-Induced Obesity in Rat Offspring Kellie L.K. Tamashiro 1 , Chantelle E. Terrillion 1 , Jayson…”
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Maternal High-Fat Diet Induces Long-Lasting Defects in Bone Structure in Rat Offspring Through Enhanced Osteoclastogenesis
Published in Calcified tissue international (01-05-2021)“…Maternal stressors during the prenatal and perinatal periods are associated with increased susceptibility for and severity of chronic disease phenotypes in…”
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A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice
Published in Psychopharmacology (01-11-2011)“…Rationale Given the contribution of cortisol dysregulation to neuropsychiatric and metabolic disorders, it is important to be able to accurately compute…”
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Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology
Published in Biological psychiatry (1969) (15-12-2010)“…Background Gene-environment interactions (GEI) are involved in the pathogenesis of mental diseases. We evaluated interaction between mutant human…”
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Prenatal stress enhances atherosclerosis and telomere shortening in ApoE knockout mouse offspring
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-07-2022)“…Children born to women who experience stress during pregnancy have an increased risk of atherosclerosis in later life, but few animal models have explored…”
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Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder
Published in Proceedings of the National Academy of Sciences - PNAS (26-09-2017)“…Genome-wide association studies have implicated the ANK3 locus in bipolar disorder, a major human psychotic illness. ANK3 encodes ankyrin-G, which organizes…”
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Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5
Published in Biochemical and biophysical research communications (13-04-2012)“…► Dose dependent increase in FK506 binding protein 5 (Fkbp5) and decrease in DNA methyltransferase 1 (Dnmt1) expression by dexamethasone. ► Site-specific loss…”
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Pleasurable behaviors reduce stress via brain reward pathways
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2010)“…Individuals often eat calorically dense, highly palatable "comfort" foods during stress for stress relief. This article demonstrates that palatable food intake…”
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Genetics and epigenetics of stress: New avenues for an old concept
Published in Neurobiology of stress (01-03-2023)Get full text
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Role of Dorsomedial Hypothalamic Neuropeptide Y in Modulating Food Intake and Energy Balance
Published in The Journal of neuroscience (07-01-2009)“…Previous studies have suggested that neuropeptide Y (NPY) in the dorsomedial hypothalamus (DMH) serves as an important signaling peptide in the regulation of…”
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Individual differences in the effects of prenatal stress exposure in rodents
Published in Neurobiology of stress (01-01-2015)“…Exposure to prenatal stress alters the phenotype of the offspring in adulthood. When the prenatal and adult environments do not match, these alterations may…”
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Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
Published in Nature medicine (01-01-2012)“…Huntington's disease is a neurodegenerative disease caused by the accumulation of mutant htt protein. Now, two groups led by Dimitri Krainc and Wenzhen Duan…”
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Large Litter Rearing Improves Leptin Sensitivity and Hypothalamic Appetite Markers in Offspring of Rat Dams Fed High-Fat Diet During Pregnancy and Lactation
Published in Endocrinology (Philadelphia) (01-09-2014)“…Maternal high-fat (HF) diet has long-term consequences on the offspring's metabolic phenotype. Here, we determined the effects of large litter (LL) rearing in…”
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Chronic social stress induces DNA methylation changes at an evolutionary conserved intergenic region in chromosome X
Published in Epigenetics (03-06-2018)“…Chronic stress resulting from prolonged exposure to negative life events increases the risk of mood and anxiety disorders. Although chronic stress can change…”
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Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake
Published in Proceedings of the National Academy of Sciences - PNAS (30-10-2007)“…Hypothalamic fatty acid metabolism has recently been implicated in the controls of food intake and energy homeostasis. We report that intracerebroventricular…”
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peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome
Published in Proceedings of the National Academy of Sciences - PNAS (06-01-2015)“…Significance Obesity and associated metabolic disorders (e.g., cardiovascular disease and type 2 diabetes) are major public health concerns. These disorders…”
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