Search Results - "Tamang, Sarah J."

AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains by Hocquemiller, Michaël, Hemsley, Kim M., Douglass, Meghan L., Tamang, Sarah J., Neumann, Daniel, King, Barbara M., Beard, Helen, Trim, Paul J., Winner, Leanne K., Lau, Adeline A., Snel, Marten F., Gomila, Cathy, Ausseil, Jérôme, Mei, Xin, Giersch, Laura, Plavsic, Mark, Laufer, Ralph

“…Patients with mucopolysaccharidosis type IIIA (MPS IIIA) lack the lysosomal enzyme sulfamidase (SGSH), which is responsible for the degradation of heparan…”
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MPS-IIIA mice acquire autistic behaviours with age by Lau, Adeline A., Tamang, Sarah J., Hemsley, Kim M.

“…Mucopolysaccharidosis (MPS) type IIIA is an inherited, neurodegenerative lysosomal storage disorder resulting from mutations in the SGSH gene. Consequently, N…”
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A novel conditional Sgsh knockout mouse model recapitulates phenotypic and neuropathic deficits of Sanfilippo syndrome by Lau, Adeline A., King, Barbara M., Thorsen, Carly L., Hassiotis, Sofia, Beard, Helen, Trim, Paul J., Whyte, Lauren S., Tamang, Sarah J., Duplock, Stephen K., Snel, Marten F., Hopwood, John J., Hemsley, Kim M.

“…Mucopolysaccharidosis (MPS) type IIIA, or Sanfilippo syndrome, is a neurodegenerative lysosomal storage disorder caused by a deficiency of the lysosomal enzyme…”
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