Search Results - "Tamaki, Shinpei"
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Identification and local manipulation of bone marrow vasculature during intravital imaging
Published in Scientific reports (14-04-2020)“…Physiological regulation of blood flow in bone marrow is important to maintain oxygen and glucose supplies but also the physiological hypoxic state of the…”
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Quantitative Analysis of Sympathetic and Nociceptive Innervation Across Bone Marrow Regions in Mice
Published in Experimental hematology (01-08-2022)“…•Innervation in various bones, the BM, and the spleen was mapped and characterized.•The site of nerve entry into the BM was clarified for each…”
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Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis
Published in eLife (04-04-2024)“…Metabolic pathways are plastic and rapidly change in response to stress or perturbation. Current metabolic profiling techniques require lysis of many cells,…”
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Correction: Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis
Published in eLife (22-10-2024)Get full text
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5
Quiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1
Published in Scientific reports (21-04-2017)“…The adult mammalian central nervous system (CNS) contains a population of slowly dividing oligodendrocyte precursor cells (OPCs), i.e., adult OPCs, which…”
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Overexpression of cyclin dependent kinase inhibitor P27/Kip1 increases oligodendrocyte differentiation from induced pluripotent stem cells
Published in In vitro cellular & developmental biology. Animal (01-09-2014)“…Cell transplantation therapy with oligodendrocyte precursor cells (OPCs) is a promising and effective treatment for diseases involving demyelination in the…”
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Distinct roles of the preparatory and payoff phases of glycolysis in hematopoietic stem cells
Published in Experimental hematology (01-08-2023)“…•Reveals distinct roles of the preparatory and payoff phases of glycolysis in hematopoietic stem cells (HSCs).•Glycolysis-defective quiescent HSCs keep…”
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Potential involvement of semaphorin 3A in maintaining intervertebral disc tissue homeostasis
Published in Journal of orthopaedic research (01-04-2019)“…ABSTRACT Intervertebral discs (IVDs) are avascular; however, ingrowth of blood vessels into their outer regions has been noted during the progression of…”
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Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis
Published in eLife (04-04-2024)“…Metabolic pathways are plastic and rapidly change in response to stress or perturbation. Current metabolic profiling techniques require lysis of many cells,…”
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Journal Article -
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Detection of residual disease in chronic myeloid leukemia utilizing genomic next generation sequencing reveals persistence of differentiated Ph+ B cells but not bone marrow stem/progenitors
Published in Leukemia & lymphoma (23-02-2021)“…Persistence of leukemic stem cells (LSCs) results in the recurrence of chronic myeloid leukemia (CML) after the administration of tyrosine kinase inhibitors…”
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11
A culture platform to study quiescent hematopoietic stem cells following genome editing
Published in Cell reports methods (19-12-2022)“…Other than genetically engineered mice, few reliable platforms are available for the study of hematopoietic stem cell (HSC) quiescence. Here we present a…”
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