Search Results - "Tamaki, Fábio K."
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H2O2 release from the very long chain acyl-CoA dehydrogenase
Published in Redox biology (01-04-2015)“…Enhanced mitochondrial generation of oxidants, including hydrogen peroxide (H2O2), is related to a large number of pathological conditions, including…”
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2
Using the Amino Acid Network to Modulate the Hydrolytic Activity of β-Glycosidases
Published in PloS one (09-12-2016)“…The active site residues in GH1 β-glycosidases are compartmentalized into 3 functional regions, involved in catalysis or binding of glycone and aglycone motifs…”
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3
Sets of covariant residues modulate the activity and thermal stability of GH1 β-glucosidases
Published in PloS one (07-05-2014)“…The statistical coupling analysis of 768 β-glucosidases from the GH1 family revealed 23 positions in which the amino acid frequencies are coupled. The roles of…”
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4
Commentary on Urinary l-erythro-β-hydroxyasparagine: a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase
Published in Bioscience reports (22-12-2021)“…The analysis of the urine contents can be informative of physiological homoeostasis, and it has been speculated that the levels of urinary d-serine (d-ser)…”
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5
Molecular insights into mechanisms of lepidopteran serine proteinase resistance to natural plant defenses
Published in Biochemical and biophysical research communications (27-11-2015)“…Plants have a wide range of chemical defenses against predation, including substances that target digestive serine proteinases of herbivorous. Previous works…”
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6
Physiology of digestion and the molecular characterization of the major digestive enzymes from Periplaneta americana
Published in Journal of insect physiology (01-11-2014)“…[Display omitted] •The Periplaneta americana major digestive enzymes had their coding sequences cloned.•Electrophoretic and chromatographic data identified…”
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The digestive system of the “stick bug” Cladomorphus phyllinus (Phasmida, Phasmatidae): A morphological, physiological and biochemical analysis
Published in Arthropod structure & development (01-03-2014)“…This work presents a detailed morphofunctional study of the digestive system of a phasmid representative, Cladomorphus phyllinus. Cells from anterior midgut…”
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A mutant β-glucosidase increases the rate of the cellulose enzymatic hydrolysis
Published in Biochemistry and biophysics reports (01-09-2016)“…The enzymatic hydrolysis of cellulose and lignocellulosic materials is marked by a rate decrease along the reaction time. Cellobiohydrolase slow dissociation…”
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Properties and secretory mechanism of Musca domestica digestive chymotrypsin and its relation with Drosophila melanogaster homologs
Published in Insect biochemistry and molecular biology (01-07-2012)“…Musca domestica larvae present two different digestive chymotryptic activities found in the posterior midgut (PMG): one major soluble activity in the lumen and…”
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10
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
Published in Journal of medicinal chemistry (23-11-2023)“…There is an urgent need for new tuberculosis (TB) treatments, with novel modes of action, to reduce the incidence/mortality of TB and to combat resistance to…”
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11
Using the Amino Acid Network to Modulate the Hydrolytic Activity of [beta]-Glycosidases
Published in PloS one (09-12-2016)“…The active site residues in GH1 [beta]-glycosidases are compartmentalized into 3 functional regions, involved in catalysis or binding of glycone and aglycone…”
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12
Conformational flexibility of the complete catalytic domain of Cdc25B phosphatases
Published in Proteins, structure, function, and bioinformatics (01-11-2016)“…ABSTRACT Cdc25B phosphatases are involved in cell cycle checkpoints and have become a possible target for developing new anticancer drugs. A more rational…”
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13
Digestive morphophysiology of Gryllodes sigillatus (Orthoptera: Gryllidae)
Published in Journal of insect physiology (01-12-2009)“…The evolution of the digestive system in the Order Orthoptera is disclosed from the study of the morphophysiology of the digestive process in its major taxa…”
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14
Sets of Covariant Residues Modulate the Activity and Thermal Stability of GH1 [beta]-Glucosidases
Published in PloS one (07-05-2014)“…The statistical coupling analysis of 768 [beta]-glucosidases from the GH1 family revealed 23 positions in which the amino acid frequencies are coupled. The…”
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15
Combining NMR and Computer Simulations to Evaluate Cdc25B Protein Flexibility
Published in Biophysical journal (28-01-2014)Get full text
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