Search Results - "Tamai, Toshikatsu"
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Programmed cell death-1 is involved with peripheral blood immune cell profiles in patients with hepatitis C virus antiviral therapy
Published in PloS one (23-05-2024)“…Mutations in the non-structural protein regions of hepatitis C virus (HCV) are a cause of a non-sustained virological response (SVR) to treatment with…”
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Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells
Published in Cancer science (01-04-2019)“…Pancreatic ductal adenocarcinoma (PDAC) is the most life‐threating disease among all digestive system malignancies. We developed a blood mRNA PDAC screening…”
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Peptide vaccine-treated, long-term surviving cancer patients harbor self-renewing tumor-specific CD8+ T cells
Published in Nature communications (03-06-2022)“…The behaviors and fates of immune cells in cancer patients, such as dysfunction and stem-like states leading to memory formation in T cells, are in intense…”
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Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET
Published in Nature communications (08-06-2022)“…Retinoic acid-inducible gene (RIG)-I is an essential innate immune sensor that recognises pathogen RNAs and induces interferon (IFN) production. However,…”
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A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma
Published in Scientific reports (04-03-2020)“…α-Fetoprotein (AFP) is considered a good target for immunotherapy strategies against hepatocellular carcinoma (HCC); however, no immunodominant AFP-derived MHC…”
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Interdisciplinary groups perform better than intradisciplinary groups in online group discussion activities
Published in Medical education online (01-01-2021)“…Online classes have been provided for health-care pre-licensure learners during the novel coronavirus disease 2019 pandemic. The purpose of this study was to…”
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Characteristics of Immune Response to Tumor‐Associated Antigens and Immune Cell Profile in Patients With Hepatocellular Carcinoma
Published in Hepatology (Baltimore, Md.) (01-02-2019)“…Host antitumor immune responses may be different between hepatocellular carcinoma (HCC) caused by metabolic disorders and HCC associated with hepatitis virus…”
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Association Between High-Avidity T-Cell Receptors, Induced by α-Fetoprotein−Derived Peptides, and Anti-Tumor Effects in Patients With Hepatocellular Carcinoma
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2017)“…Background & Aims Levels of α-fetoprotein (AFP) are measured for surveillance and diagnosis of hepatocellular carcinoma (HCC). We performed a phase 1 trial to…”
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Characteristics of Impaired Dendritic Cell Function in Patients With Hepatitis B Virus Infection
Published in Hepatology (Baltimore, Md.) (01-07-2019)“…Dendritic cells (DCs) are antigen‐presenting cells with a central role in host immune response. This study analyzed gene expression and DC function in…”
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Feasibility and reliability of the pandemic-adapted online-onsite hybrid graduation OSCE in Japan
Published in Advances in health sciences education : theory and practice (01-07-2024)“…Objective structured clinical examination (OSCE) is widely used to assess medical students’ clinical skills. Virtual OSCEs were used in place of in-person…”
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Immune responses against tumour‐associated antigen‐derived cytotoxic T lymphocyte epitopes in cholangiocarcinoma patients
Published in Liver international (01-11-2018)“…Background & Aims Immunotherapy is a promising treatment option for cholangiocarcinoma. We compared cytotoxic T lymphocyte (CTL) responses against several…”
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Immune response to human telomerase reverse transcriptase‐derived helper T cell epitopes in hepatocellular carcinoma patients
Published in Liver international (01-09-2018)“…Background and Aims Human telomerase reverse transcriptase is a catalytic enzyme involved in telomere elongation. It is expressed in many tumours, including…”
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13
Programmed cell death-1 is involved with peripheral blood immune cell profiles in patients with hepatitis C virus antiviral therapy
Published in PloS one (01-01-2024)“…Mutations in the non-structural protein regions of hepatitis C virus (HCV) are a cause of a non-sustained virological response (SVR) to treatment with…”
Get full text
Journal Article