Search Results - "Tamai, Katsuto"

Footprint-free gene mutation correction in induced pluripotent stem cell (iPSC) derived from recessive dystrophic epidermolysis bullosa (RDEB) using the CRISPR/Cas9 and piggyBac transposon system by Itoh, Munenari, Kawagoe, Shiho, Tamai, Katsuto, Nakagawa, Hidemi, Asahina, Akihiko, Okano, Hirotaka James

“…•We corrected a gene mutation in RDEB-specific iPSC without any footprint.•CRISPR/Cas9 is an easy-designed and efficient tool for gene editing.•piggyBac…”
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Circulating Bone Marrow‐Derived Osteoblast Progenitor Cells Are Recruited to the Bone‐Forming Site by the CXCR4/Stromal Cell‐Derived Factor‐1 Pathway by Otsuru, Satoru, Tamai, Katsuto, Yamazaki, Takehiko, Yoshikawa, Hideki, Kaneda, Yasufumi

“…Previous studies demonstrated the existence of osteoblastic cells in circulating blood. Recently, we reported that osteoblast progenitor cells (OPCs) in…”
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Receptor for Advanced Glycation End Products-Mediated Signaling Impairs the Maintenance of Bone Marrow Mesenchymal Stromal Cells in Diabetic Model Mice by Aikawa, Eriko, Fujita, Ryo, Asai, Maiko, Kaneda, Yasufumi, Tamai, Katsuto

“…Bone marrow mesenchymal stromal cells (BM-MSCs) have been demonstrated to contribute to tissue regeneration. However, chronic pathological conditions, such as…”
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Current topics in Epidermolysis bullosa: Pathophysiology and therapeutic challenges by Natsuga, Ken, Shinkuma, Satoru, Hsu, Chao-Kai, Fujita, Yasuyuki, Ishiko, Akira, Tamai, Katsuto, McGrath, John A.

“…Epidermolysis bullosa (EB) is a group of inherited skin and mucosal fragility disorders resulting from mutations in genes encoding basement membrane zone (BMZ)…”
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Plap-1 lineage tracing and single-cell transcriptomics reveal cellular dynamics in the periodontal ligament by Iwayama, Tomoaki, Iwashita, Mizuho, Miyashita, Kazuya, Sakashita, Hiromi, Matsumoto, Shuji, Tomita, Kiwako, Bhongsatiern, Phan, Kitayama, Tomomi, Ikegami, Kentaro, Shimbo, Takashi, Tamai, Katsuto, Murayama, Masanori A, Ogawa, Shuhei, Iwakura, Yoichiro, Yamada, Satoru, Olson, Lorin E, Takedachi, Masahide, Murakami, Shinya

“…Periodontal tissue supports teeth in the alveolar bone socket via fibrous attachment of the periodontal ligament (PDL). The PDL contains periodontal…”
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PDGFRα-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia by Tamai, Katsuto, Yamazaki, Takehiko, Chino, Takenao, Ishii, Masaru, Otsuru, Satoru, Kikuchi, Yasushi, Iinuma, Shin, Saga, Kotaro, Nimura, Keisuke, Shimbo, Takashi, Umegaki, Noriko, Katayama, Ichiro, Miyazaki, Jun-ichi, Takeda, Junji, McGrath, John A., Uitto, Jouni, Kaneda, Yasufumi, Prockop, Darwin J.

“…The role of bone marrow cells in repairing ectodermal tissue, such as skin epidermis, is not clear. To explore this process further, this study examined a…”
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The administration of high-mobility group box 1 fragment prevents deterioration of cardiac performance by enhancement of bone marrow mesenchymal stem cell homing in the delta-sarcoglycan-deficient hamster by Kido, Takashi, Miyagawa, Shigeru, Goto, Takasumi, Tamai, Katsuto, Ueno, Takayoshi, Toda, Koichi, Kuratani, Toru, Sawa, Yoshiki

“…We hypothesized that systemic administration of high-mobility group box 1 fragment attenuates the progression of myocardial fibrosis and cardiac dysfunction in…”
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High-mobility group box 1 fragment suppresses adverse post-infarction remodeling by recruiting PDGFRα-positive bone marrow cells by Goto, Takasumi, Miyagawa, Shigeru, Tamai, Katsuto, Matsuura, Ryohei, Kido, Takashi, Kuratani, Toru, Shimamura, Kazuo, Sakaniwa, Ryoto, Harada, Akima, Sawa, Yoshiki

“…High-mobility group box 1 protein (HMGB1) fragment enhances bone marrow-derived mesenchymal stem cell (BM-MSC) recruitment to damaged tissue to promote tissue…”
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Novel Autologous Cell Therapy in Ischemic Limb Disease Through Growth Factor Secretion by Cultured Adipose Tissue–Derived Stromal Cells by Nakagami, Hironori, Maeda, Kazuhisa, Morishita, Ryuichi, Iguchi, Sota, Nishikawa, Tomoyuki, Takami, Yoichi, Kikuchi, Yasushi, Saito, Yukihiro, Tamai, Katsuto, Ogihara, Toshio, Kaneda, Yasufumi

“…OBJECTIVE—The delivery of autologous progenitor cells into ischemic tissue of patients is emerging as a novel therapeutic option. Here, we report the potential…”
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Controlled induction of immune tolerance by mesenchymal stem cells transferred by maternal microchimerism by Iwai, Sayuri, Okada, Aiko, Sasano, Kei, Endo, Masayuki, Yamazaki, Sho, Wang, Xin, Shimbo, Takashi, Tomimatsu, Takuji, Kimura, Tadashi, Tamai, Katsuto

“…Feto-maternal immune tolerance is established during pregnancy; however, its mechanism and maintenance remain underexplored. Here, we investigated whether…”
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Chromatin accessibility identifies diversity in mesenchymal stem cells from different tissue origins by Ho, Yen-Ting, Shimbo, Takashi, Wijaya, Edward, Ouchi, Yuya, Takaki, Eiichi, Yamamoto, Ryoma, Kikuchi, Yasushi, Kaneda, Yasufumi, Tamai, Katsuto

“…Mesenchymal stem cells (MSCs), which can differentiate into tri-lineage (osteoblast, adipocyte, and chondrocyte) and suppress inflammation, are promising tools…”
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Cut-C: cleavage under tethered nuclease for conformational capture by Shimbo, Takashi, Kawamura, Machika, Wijaya, Edward, Takaki, Eiichi, Kaneda, Yasufumi, Tamai, Katsuto

“…Deciphering the 3D structure of the genome is essential for elucidating the regulatory mechanisms of gene expression in detail. Existing methods, such as…”
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Systemic circulation and bone recruitment of osteoclast precursors tracked by using fluorescent imaging techniques by Kotani, Manato, Kikuta, Junichi, Klauschen, Frederick, Chino, Takenao, Kobayashi, Yasuhiro, Yasuda, Hisataka, Tamai, Katsuto, Miyawaki, Atsushi, Kanagawa, Osami, Tomura, Michio, Ishii, Masaru

“…Osteoclasts are bone-resorbing polykaryons differentiated from monocyte/macrophage-lineage hematopoietic precursors. It remains unclear whether osteoclasts…”
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Synthesized HMGB1 peptide prevents the progression of inflammation, steatosis, fibrosis, and tumor occurrence in a non‐alcoholic steatohepatitis mouse model by Ishii, Yui, Tsuchiya, Atsunori, Natsui, Kazuki, Koseki, Youhei, Takeda, Nobutaka, Tomiyoshi, Kei, Yamazaki, Fusako, Yoshida, Yuki, Shimbo, Takashi, Tamai, Katsuto, Terai, Shuji

“…Aim Non‐alcoholic steatohepatitis (NASH) with fibrosis eventually leads to cirrhosis and hepatocellular carcinoma. Thus, the development of therapies other…”
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A Novel Quantitative Evaluation of Bone Formation After Opening Wedge High Tibial Osteotomy Using Tomosynthesis by Ishibashi, Kyota, Sasaki, Eiji, Wijaya, Edward, Yamauchi, Shohei, Sasaki, Shizuka, Kimura, Yuka, Yamamoto, Yuji, Shimbo, Takashi, Tamai, Katsuto, Ishibashi, Yasuyuki

“…This study aimed to establish and validate a novel evaluation method using digital tomosynthesis to quantify bone formation in the gap after opening wedge high…”
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Longitudinal Single-Cell Transcriptomics Reveals a Role for Serpina3n-Mediated Resolution of Inflammation in a Mouse Colitis Model by Ho, Yen-Ting, Shimbo, Takashi, Wijaya, Edward, Kitayama, Tomomi, Takaki, Satoshi, Ikegami, Kentaro, Miyashita, Kazuya, Ouchi, Yuya, Takaki, Eiichi, Yamamoto, Ryoma, Kaneda, Yasufumi, Tamai, Katsuto

“…Proper resolution of inflammation is essential to maintaining homeostasis, which is important as a dysregulated inflammatory response has adverse consequences,…”
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Successful High-Dose Radiation Treatment for Chemo-Resistant Oral Squamous Cell Carcinoma in a Kindler's Syndrome Patient by Kimura, Yuka, Tanemura, Atsushi, Hanaoka, Yuma, Kiyohara, Eiji, Wataya-Kaneda, Mari, Fujimoto, Manabu, Tamai, Katsuto, Tamari, Keisuke, Seo, Yuji, Ogawa, Kazuhiko

“…KCI Citation Count: 0…”
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Recessive dystrophic epidermolysis bullosa with extensive transplantation of cultured epidermal autograft product after cardiopulmonary resuscitation: A case report by Mori, Shiho, Shimbo, Takashi, Kimura, Yuka, Hayashi, Mami, Kiyohara, Eiji, Fukui, Miho, Watanabe, Miho, Bessho, Kazuhiko, Fujimoto, Manabu, Tamai, Katsuto

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Endogenous Mesenchymal Stromal Cells in Bone Marrow Are Required to Preserve Muscle Function in mdx Mice by Fujita, Ryo, Tamai, Katsuto, Aikawa, Eriko, Nimura, Keisuke, Ishino, Saki, Kikuchi, Yasushi, Kaneda, Yasufumi

“…The physiological role of “endogenous” bone marrow (BM) mesenchymal stromal cells (MSCs) in tissue regeneration is poorly understood. Here, we show the…”
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Single-cell transcriptome analysis reveals cellular heterogeneity in mouse intra- and extra articular ligaments by Ishibashi, Kyota, Ikegami, Kentaro, Shimbo, Takashi, Sasaki, Eiji, Kitayama, Tomomi, Nakamura, Yuzuru, Tsushima, Takahiro, Ishibashi, Yasuyuki, Tamai, Katsuto

“…Ligaments are collagenous connective tissues that connect bones. Injury of knee ligaments, namely anterior cruciate ligament (ACL) and medial collateral…”
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