Search Results - "Tamás, A"

Peptides Containing β‑Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry by Cabrele, Chiara, Martinek, Tamás A, Reiser, Oliver, Berlicki, Łukasz

“…The construction of bioactive peptides using β-amino acid-containing sequence patterns is a very promising strategy to obtain analogues that exhibit properties…”
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Peptidic foldamers: ramping up diversity by Martinek, Tamás A, Fülöp, Ferenc

“…Non-natural folded polymers (foldamers) display considerable versatility, and the design of such molecules is of great current interest. In this respect,…”
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Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides by Lázár, Viktória, Martins, Ana, Spohn, Réka, Daruka, Lejla, Grézal, Gábor, Fekete, Gergely, Számel, Mónika, Jangir, Pramod K, Kintses, Bálint, Csörgő, Bálint, Nyerges, Ákos, Györkei, Ádám, Kincses, András, Dér, András, Walter, Fruzsina R, Deli, Mária A, Urbán, Edit, Hegedűs, Zsófia, Olajos, Gábor, Méhi, Orsolya, Bálint, Balázs, Nagy, István, Martinek, Tamás A, Papp, Balázs, Pál, Csaba

“…Antimicrobial peptides are promising alternative antimicrobial agents. However, little is known about whether resistance to small-molecule antibiotics leads to…”
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Light-Fueled Primitive Replication and Selection in Biomimetic Chemical Systems by Bartus, Éva, Tököli, Attila, Mag, Beáta, Bajcsi, Áron, Kecskeméti, Gábor, Wéber, Edit, Kele, Zoltán, Fenteany, Gabriel, Martinek, Tamás A.

“…The concept of chemically evolvable replicators is central to abiogenesis. Chemical evolvability requires three essential components: energy-harvesting…”
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Tilted State Population of Antimicrobial Peptide PGLa Is Coupled to the Transmembrane Potential by Németh, Lukács J., Martinek, Tamás A., Jójárt, Balázs

“…Cationic antimicrobial peptide PGLa gets into close contact with the anionic bacterial cell membrane, facilitating cross-membrane transport phenomena and…”
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Three-sublattice ordering of the SU(3) Heisenberg model of three-flavor fermions on the square and cubic lattices by Tóth, Tamás A, Läuchli, Andreas M, Mila, Frédéric, Penc, Karlo

“…Combining a semiclassical analysis with exact diagonalizations, we show that the ground state of the SU(3) Heisenberg model on the square lattice develops…”
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Fluid Networks Assembled from Endoskeletal Droplets by Prileszky, Tamás A, Furst, Eric M

“…Anisotropic endoskeletal droplets are produced continuously in a microfluidic device. The device temperature is controlled such that droplets are formed in a…”
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Model of Structured Emulsion Droplet Stability and Reconfigurability by Bayles, Alexandra V, Prileszky, Tamás A, Spicer, Patrick T, Furst, Eric M

“…A model of internally structured emulsion droplets is presented that accounts for the traction forces generated by interfacial tension and the von Mises yield…”
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De novo design of potential peptide analogs against the main protease of Omicron variant using in silico studies by M L, Stanly Paul, Kumari, Sonia, Martinek, Tamás A, M, Elizabeth Sobhia

“…SARS-CoV-2 and its variants are crossing the immunity barrier induced through vaccination. Recent Omicron sub-variants are highly transmissible and have a low…”
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Performance of the general amber force field in modeling aqueous POPC membrane bilayers by Jójárt, Balázs, Martinek, Tamás A.

“…The aim of this work was to answer the question of whether the general amber force field (GAFF) is good enough to simulate fully hydrated POPC membrane…”
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Promiscuity mapping of the S100 protein family using a high-throughput holdup assay by Simon, Márton A., Bartus, Éva, Mag, Beáta, Boros, Eszter, Roszjár, Lea, Gógl, Gergő, Travé, Gilles, Martinek, Tamás A., Nyitray, László

“…S100 proteins are small, typically homodimeric, vertebrate-specific EF-hand proteins that establish Ca 2+ -dependent protein–protein interactions in the intra-…”
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Target-templated Construction of Functional Proteomimetics Using Photo-foldamer Libraries by Wéber, Edit, Ábrányi-Balogh, Péter, Martinek, Tamas A, Nagymihály, Bence, Menyhárd, Dóra Karancsiné, Péczka, Nikolett, Gadanecz, Márton, Schlosser, Gitta, Orgován, Zoltán, Bogár, Ferenc, Bajusz, Dávid, Kecskeméti, Gábor, Szabó, Zoltán, Bartus, Éva, Tököli, Attila, Tóth, Gábor K, Szalai, Tibor V, Takács, Tamás, de Araujo, Elvin, Buday, László, Perczel, András, Keserű, György M

“…Current methods for proteomimetic engineering rely on structure-based design. Here we describe a design strategy that allows the construction of proteomimetics…”
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Design of Peptidic Foldamer Helices: A Stereochemical Patterning Approach by Mándity, István M, Wéber, Edit, Martinek, Tamás A, Olajos, Gábor, Tóth, Gábor K, Vass, Elemér, Fülöp, Ferenc

“…Assembly language: The programmed sequences of stereochemical building blocks lead to novel biomimetic helices. The rational design approach offers new…”
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A Painter’s Version: Amenhotep, Son of Amunnakhte and Pictorial Tradition by Bács, Tamás A.

“…Arguably one of the most remarkable painters/draughtsmen, not only in his direct surroundings of Deir el-Medina but in the history of New Kingdom painting…”
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Phosphine(III)‐Triggered One‐Pot Domino Sequences towards 5,6‐Dihydropyridine‐2‐(1H)‐One and Pyridine‐2(1H)‐One Scaffolds by Makra, Zsófia, Madácsi, Ramóna, Martinek, Tamás A., Bényei, Attila, Puskás, László G., Gyuris, Márió, Kanizsai, Iván

“…An elegant P(nBu)3‐triggered synthetic approach has been developed towards multisubstituted 5,6‐dihydropyridin‐2(1H)‐one and pyridin‐2(1H)‐one derivatives…”
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DPP‐4 Cleaves α/β‐Peptide Bonds: Substrate Specificity and Half‐Lives by Turalić, Amila, Đeđibegović, Jasmina, Hegedüs, Zsófia, Martinek, Tamás A.

“…The incorporation of β‐amino acids into a peptide sequence has gained particular attention as β‐ and α/β‐peptides have shown remarkable proteolytic stability,…”
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Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid by Berlicki, Łukasz, Pilsl, Ludwig, Wéber, Edit, Mándity, István M., Cabrele, Chiara, Martinek, Tamás A., Fülöp, Ferenc, Reiser, Oliver

“…Waterproof: cis‐β‐Aminocylopentanecarboxylic acid is a highly suitable building block for the synthesis of α,β‐ and α,α,β,β‐peptides that have unique helical…”
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Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers by Bartus, Éva, Olajos, Gábor, Schuster, Ildikó, Bozsó, Zsolt, Deli, Mária A, Veszelka, Szilvia, Walter, Fruzsina R, Datki, Zsolt, Szakonyi, Zsolt, Martinek, Tamás A, Fülöp, Livia

“…Alzheimer's disease is one of the most common chronic neurodegenerative disorders. Despite several in vivo and clinical studies, the cause of the disease is…”
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Chemically diverse antimicrobial peptides induce hyperpolarization of the E. coli membrane by Bhaumik, Kaushik Nath, Spohn, Réka, Dunai, Anett, Daruka, Lejla, Olajos, Gábor, Zákány, Florina, Hetényi, Anasztázia, Pál, Csaba, Martinek, Tamás A.

“…The negative membrane potential within bacterial cells is crucial in various essential cellular processes. Sustaining a hyperpolarised membrane could offer a…”
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Building β-Peptide H10/12 Foldamer Helices with Six-Membered Cyclic Side-Chains: Fine-Tuning of Folding and Self-Assembly by Mándity, István M, Fülöp, Livia, Vass, Elemér, Tóth, Gábor K, Martinek, Tamás A, Fülöp, Ferenc

“…The ability of the β-peptidic H10/12 helix to tolerate side-chains containing six-membered alicyclic rings was studied. cis-2-Aminocyclohex-3-ene carboxylic…”
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