Search Results - "Tam, Wai‐Keung"
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Experience of chromosomal microarray applied in prenatal and postnatal settings in Hong Kong
Published in American journal of medical genetics. Part C, Seminars in medical genetics (01-06-2019)“…Chromosomal microarray (CMA) is recommended as a first tier investigation for patients with developmental delay (DD), intellectual disability (ID), autistic…”
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Prenatal diagnosis and long‐term follow‐up of a Chinese patient with mosaic variegated aneuploidy and its molecular analysis
Published in Clinical case reports (01-08-2020)“…Mosaic variegated aneuploidy (MVA) is a rare genetic disorder caused by mutations in BUB1B, CEP57, or TRIP13. We describe the prenatal diagnosis, molecular…”
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Spleen Tyrosine Kinase: A Crucial Player and Potential Therapeutic Target in Renal Disease
Published in Nephron (2015) (01-01-2016)“…Spleen tyrosine kinase (Syk), a 72 kDa cytoplasmic non-receptor protein-tyrosine kinase, plays an important role in signal transduction in a variety of cell…”
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Failing to Treat: Why Public Hospitals in China Do Not Work
Published in China review (Hong Kong, China : 1991) (01-10-2008)“…This article examines the institutional origins of the prevalent failures of Chinese public hospitals to treat indigent patients from the perspective of…”
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Cost-effectiveness analysis of chromosomal microarray as a primary test for prenatal diagnosis in Hong Kong
Published in BMC pregnancy and childbirth (14-02-2020)“…Chromosomal microarray (CMA) has been shown to be cost-effective over karyotyping in invasive prenatal diagnosis for pregnancies with fetal ultrasound…”
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Real-world study of the multimorbidity and health service utilisation among individuals with non-diabetic hyperglycemia and type 2 diabetes mellitus in North West London
Published in BMJ open diabetes research & care (08-08-2024)“…IntroductionThe prevalence of non-diabetic hyperglycemia (NDH) and type 2 diabetes mellitus (T2DM) is increasing. While T2DM is recognised to be associated…”
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E-health in the East Asian tigers
Published in International journal of medical informatics (Shannon, Ireland) (01-11-2004)“…The article analyzes e-health progress in East Asia's leading tiger economies: Japan, Hong Kong, Singapore, South Korea and Taiwan. It describes five main…”
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Targeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond
Published in Nephrology, dialysis, transplantation (01-01-2017)“…Glomerulonephritis (GN) affects patients of all ages and is an important cause of morbidity and mortality. Non-selective immunosuppressive drugs have been used…”
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Pkd2 Dosage Influences Cellular Repair Responses following Ischemia-Reperfusion Injury
Published in The American journal of pathology (01-10-2009)“…Autosomal dominant polycystic kidney disease (ADPKD) results from mutations in either PKD1 or PKD2 and accounts for 10% of all patients on renal replacement…”
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Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression
Published in Kidney international (01-07-2015)“…Spleen tyrosine kinase (SYK) is an important component of the intracellular signaling pathway for various immunoreceptors. Inhibition of SYK has shown promise…”
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Prenatal diagnosis and long-term follow-up of a Chinese patient with mosaic variegated aneuploidy and its molecular analysis
Published in Clinical case reports (01-08-2020)“…Mosaic variegated aneuploidy (MVA) is a rare genetic disorder caused by mutations in BUB1B, CEP57, or TRIP13. We describe the prenatal diagnosis, molecular…”
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