Search Results - "Tam, Jenny"

A Novel Dual Fluorochrome Near-Infrared Imaging Probe for Potential Alzheimer's Enzyme Biomarkers-BACE1 and Cathepsin D by Tam, Jenny M, Josephson, Lee, Pilozzi, Alexander R, Huang, Xudong

“…A molecular imaging probe to fluorescently image the β-site of the amyloid precursor protein (APP) cleaving enzyme 1 (BACE1) and cathepsin D (CatD) enzymes…”
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Barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel in situ analyses by Liu, Songlei, Punthambaker, Sukanya, Iyer, Eswar P R, Ferrante, Thomas, Goodwin, Daniel, Fürth, Daniel, Pawlowski, Andrew C, Jindal, Kunal, Tam, Jenny M, Mifflin, Lauren, Alon, Shahar, Sinha, Anubhav, Wassie, Asmamaw T, Chen, Fei, Cheng, Anne, Willocq, Valerie, Meyer, Katharina, Ling, King-Hwa, Camplisson, Conor K, Kohman, Richie E, Aach, John, Lee, Je Hyuk, Yankner, Bruce A, Boyden, Edward S, Church, George M

“…Abstract We present barcoded oligonucleotides ligated on RNA amplified for multiplexed and parallel insitu analyses (BOLORAMIS), a reverse transcription-free…”
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Simultaneous Monitoring of Multi-Enzyme Activity and Concentration in Tumor Using a Triply Labeled Fluorescent In Vivo Imaging Probe by Tam, Jenny, Pilozzi, Alexander, Mahmood, Umar, Huang, Xudong

“…The use of fluorescent imaging probes that monitor the activity of proteases that experience an increase in expression and activity in tumors is well…”
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Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability by Jo, Charles, Zhang, Jing, Tam, Jenny M., Church, George M., Khalil, Ahmad S., Segrè, Daniel, Tang, Tzu-Chieh

“…Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through its interactions with growing and decaying flora and their…”
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Impaired neural stress resistance and loss of REST in bipolar disorder by Meyer, Katharina, Ling, King-Hwa, Yeo, Pei-Ling, Spathopoulou, Angeliki, Drake, Derek, Choi, Jaejoon, Aron, Liviu, Garcia-Corral, Mariana, Ko, Tak, Lee, Eunjung Alice, Tam, Jenny M., Perlis, Roy H., Church, George M., Tsai, Li-Huei, Yankner, Bruce A.

“…Neurodevelopmental changes and impaired stress resistance have been implicated in the pathogenesis of bipolar disorder (BD), but the underlying regulatory…”
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αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells by Acharya, Mridu, Sokolovska, Anna, Tam, Jenny M., Conway, Kara L., Stefani, Caroline, Raso, Fiona, Mukhopadhyay, Subhankar, Feliu, Marianela, Paul, Elahna, Savill, John, Hynes, Richard O., Xavier, Ramnik J., Vyas, Jatin M., Stuart, Lynda M., Lacy-Hulbert, Adam

“…Integrin signalling triggers cytoskeletal rearrangements, including endocytosis and exocytosis of integrins and other membrane proteins. In addition to…”
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Dectin-1-Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages by Tam, Jenny M., Mansour, Michael K., Khan, Nida S., Seward, Michael, Puranam, Sravanthi, Tanne, Antoine, Sokolovska, Anna, Becker, Christine E., Acharya, Mridu, Baird, Michelle A., Choi, Augustine M. K., Davidson, Michael W., Segal, Brahm H., Lacy-Hulbert, Adam, Stuart, Lynda M., Xavier, Ramnik J., Vyas, Jatin M.

“…Autophagy has been postulated to play role in mammalian host defense against fungal pathogens, although the molecular details remain unclear. Here, we show…”
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Transcriptomic analysis of pathways associated with ITGAV/alpha(v) integrin-dependent autophagy in human B cells by Muir, Virginia, Sagadiev, Sara, Liu, Shuozhi, Holder, Ursula, Armendariz, Andrea M., Suchland, Emmaline, Meitlis, Iana, Camp, Nathan, Giltiay, Natalia, Tam, Jenny M., Garner, Ethan C., Wivagg, Carl N., Shows, Donna, James, Richard G., Lacy-Hulbert, Adam, Acharya, Mridu

“…Macroautophagy/autophagy proteins have been linked with the development of immune-mediated diseases including lupus, but the mechanisms for this are unclear…”
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PKC‐δ activation in neutrophils promotes fungal clearance by Li, Xun, Cullere, Xavier, Nishi, Hiroshi, Saggu, Gurpanna, Durand, Enrique, Mansour, Michael K., Tam, Jenny M., Song, Xiu‐yu, Lin, Xin, Vyas, Jatin M., Mayadas, Tanya

“…PKCδ is essential for neutrophil, but not macrophage functions required for host defense against fungal pathogens. The C‐type lectin receptor dectin‐1 and the…”
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Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing β-1,3 Glucan by Khan, Nida S, Kasperkovitz, Pia V, Timmons, Allison K, Mansour, Michael K, Tam, Jenny M, Seward, Michael W, Reedy, Jennifer L, Puranam, Sravanthi, Feliu, Marianela, Vyas, Jatin M

“…Dectin-1 and TLR9 play distinct roles in the recognition and induction of innate immune responses to Aspergillus fumigatus and Candida albicans. Dectin-1 is a…”
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Dectin-1 Activation Controls Maturation of β-1,3-Glucan-containing Phagosomes by Mansour, Michael K., Tam, Jenny M., Khan, Nida S., Seward, Michael, Davids, Peter J., Puranam, Sravanthi, Sokolovska, Anna, Sykes, David B., Dagher, Zeina, Becker, Christine, Tanne, Antoine, Reedy, Jennifer L., Stuart, Lynda M., Vyas, Jatin M.

“…Elimination of fungal pathogens by phagocytes requires phagosome maturation, a process that involves the recruitment and fusion of intracellular proteins. The…”
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Anomalous COVID-19 tests hinder researchers by Robinson-McCarthy, Lindsey R, Mijalis, Alexander J, Filsinger, Gabriel T, de Puig, Helena, Donghia, Nina M, Schaus, Thomas E, Rasmussen, Robert A, Ferreira, Raphael, Lunshof, Jeantine E, Chao, George, Ter-Ovanesyan, Dmitry, Dodd, Oliver, Kuru, Erkin, Sesay, Adama M, Rainbow, Joshua, Pawlowski, Andrew C, Wannier, Timothy M, Yin, Peng, Collins, James J, Ingber, Donald E, Church, George M, Tam, Jenny M

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Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans by Tam, Jenny M, Reedy, Jennifer L, Lukason, Daniel P, Kuna, Sunnie G, Acharya, Mridu, Khan, Nida S, Negoro, Paige E, Xu, Shuying, Ward, Rebecca A, Feldman, Michael B, Dutko, Richard A, Jeffery, Jane B, Sokolovska, Anna, Wivagg, Carl N, Lassen, Kara G, Le Naour, François, Matzaraki, Vasiliki, Garner, Ethan C, Xavier, Ramnik J, Kumar, Vinod, van de Veerdonk, Frank L, Netea, Mihai G, Miranti, Cindy K, Mansour, Michael K, Vyas, Jatin M

“…Tetraspanins are a family of proteins possessing four transmembrane domains that help in lateral organization of plasma membrane proteins. These proteins…”
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CD82 controls CpG‐dependent TLR9 signaling by Khan, Nida S., Lukason, Daniel P., Feliu, Marianela, Ward, Rebecca A., Lord, Allison K., Reedy, Jennifer L., Ramirez‐Ortiz, Zaida G., Tam, Jenny M., Kasperkovitz, Pia V., Negoro, Paige E., Vyas, Tammy D., Xu, Shuying, Brinkmann, Melanie M., Acharaya, idu, Artavanis‐Tsakonas, Katerina, Frickel, Eva‐Maria, Becker, Christine E., Dagher, Zeina, Kim, You‐Me, Latz, Eicke, Ploegh, Hidde L., Mansour, Michael K., Miranti, Cindy K., Levitz, Stuart M., Vyas, Jatin M.

“…The tetraspanin CD82 is a potent suppressor of tumor metastasis and regulates several processes including signal transduction, cell adhesion, motility, and…”
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Toll-Like Receptor 9 Modulates Macrophage Antifungal Effector Function during Innate Recognition of Candida albicans and Saccharomyces cerevisiae by KASPERKOVITZ, Pia V, KHAN, Nida S, TAM, Jenny M, MANSOUR, Michael K, DAVIDS, Peter J, VYAS, Jatin M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Fluorescent Tracking of Yeast Division Clarifies the Essential Role of Spleen Tyrosine Kinase in the Intracellular Control of Candida glabrata in Macrophages by Dagher, Zeina, Xu, Shuying, Negoro, Paige E, Khan, Nida S, Feldman, Michael B, Reedy, Jennifer L, Tam, Jenny M, Sykes, David B, Mansour, Michael K

“…Macrophages play a critical role in the elimination of fungal pathogens. They are sensed cell surface pattern-recognition receptors and are phagocytosed into…”
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The cell biology of the innate immune response to Aspergillus fumigatus by Mansour, Michael K., Tam, Jenny M., Vyas, Jatin M.

“…The development of invasive aspergillosis is a feared complication for immunocompromised patients. Despite the use of antifungal agents with excellent…”
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The Carbohydrate Lectin Receptor Dectin-1 Mediates the Immune Response to Exserohilum rostratum by Reedy, Jennifer L, Negoro, Paige E, Feliu, Marianela, Lord, Allison K, Khan, Nida S, Lukason, Dan P, Wiederhold, Nathan P, Tam, Jenny M, Mansour, Michael K, Patterson, Thomas F, Vyas, Jatin M

“…Dematiaceous molds are found ubiquitously in the environment and cause a wide spectrum of human disease, including infections associated with high rates of…”
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Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy by Begun, Jakob, Lassen, Kara G., Jijon, Humberto B., Baxt, Leigh A., Goel, Gautam, Heath, Robert J., Ng, Aylwin, Tam, Jenny M., Kuo, Szu-Yu, Villablanca, Eduardo J., Fagbami, Lola, Oosting, Marije, Kumar, Vinod, Schenone, Monica, Carr, Steven A., Joosten, Leo A.B., Vyas, Jatin M., Daly, Mark J., Netea, Mihai G., Brown, Gordon D., Wijmenga, Cisca, Xavier, Ramnik J.

“…The polymorphism ATG16L1 T300A, associated with increased risk of Crohn’s disease, impairs pathogen defense mechanisms including selective autophagy, but…”
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The Known Unknowns of the Immune Response to Coccidioides by Ward, Rebecca A, Thompson, 3rd, George R, Villani, Alexandra-Chloé, Li, Bo, Mansour, Michael K, Wuethrich, Marcel, Tam, Jenny M, Klein, Bruce S, Vyas, Jatin M

“…Coccidioidomycosis, otherwise known as Valley Fever, is caused by the dimorphic fungi and . While most clinical cases present with self-limiting pulmonary…”
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