Search Results - "Tam, D."
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Pd/C as a Catalyst for Completely Regioselective CH Functionalization of Thiophenes under Mild Conditions
Published in Angewandte Chemie International Edition (10-02-2014)“…The completely C3‐selective arylation of thiophenes and benzo[b]thiophenes was achieved by using Pd/C as a heterogeneous catalyst without ligands or additives…”
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Ruthenium-NHC-Catalyzed Asymmetric Hydrogenation of Indolizines: Access to Indolizidine Alkaloids
Published in Angewandte Chemie International Edition (02-09-2013)“…Crossing N‐bridges! A ruthenium/N‐heterocyclic carbene (NHC) complex serves as the catalyst for the high‐yielding and completely regioselective and asymmetric…”
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3
Completely Regioselective Direct C–H Functionalization of Benzo[b]thiophenes Using a Simple Heterogeneous Catalyst
Published in Journal of the American Chemical Society (22-05-2013)“…The first completely selective C3 C–H arylation of benzo[b]thiophenes is reported, demonstrating previously unexploited reactivity of palladium…”
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On the distribution of zeros of linear combinations of Dirichlet L-functions on the critical line
Published in Acta mathematica Hungarica (01-06-2023)“…Let χ be a primitive Dirichlet character. Let ε be an arbitrary positive number. We study the distribution of zeros of the function G ( t ) = a 1 Z ( t , χ 1 )…”
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Breast cancer in the transgender population; a systematic review
Published in Breast (Edinburgh) (01-04-2024)Get full text
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6
Human B-1 cells take the stage
Published in Annals of the New York Academy of Sciences (01-05-2013)“…B‐1 cells play critical roles in defending against microbial invasion and in housekeeping removal of cellular debris. B‐1 cells secrete natural antibody and…”
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C-H arylation of triphenylene, naphthalene and related arenes using Pd/C
Published in Chemical science (Cambridge) (01-03-2015)“…A highly selective arylation of a number of polyaromatic hydrocarbons (PAHs) with aryliodonium salts and Pd/C as the only reagent is reported. The first C-H…”
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A phase I trial of PRN1008, a novel reversible covalent inhibitor of Bruton's tyrosine kinase, in healthy volunteers
Published in British journal of clinical pharmacology (01-11-2017)“…Aim To evaluate the safety, tolerability, and pharmacokinetics/pharmacodynamics of PRN1008, a novel Bruton's tyrosine kinase (BTK) inhibitor, in healthy…”
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Electrochemically assisted synthesis of ultra-small Ru@IrOx core-shell nanoparticles for water splitting electro-catalysis
Published in Electrochimica acta (01-05-2020)“…Carbon-free use of hydrogen as a clean fuel and a viable energy storage medium has been impeded by the efficiency of water electrolysis, which in turn, is…”
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10
Au‐Cavitand Catalyzed Alkyne‐Acid Cyclizations
Published in European journal of organic chemistry (08-09-2019)“…Supramolecular cavitands that contain inwardly directed functional groups have yielded specialized transformations and trapping of reactive intermediates. A…”
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Recent advances in dengue pathogenesis and clinical management
Published in Vaccine (10-12-2015)“…Abstract This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines…”
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Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age
Published in Frontiers in immunology (19-03-2019)“…Age-related deficits in the immune system have been associated with an increased incidence of infections, autoimmune diseases, and cancer. Human B cell…”
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13
Step‐Edge Assisted Direct Linear Alkane Coupling
Published in Chemistry : a European journal (02-05-2017)“…Direct coupling of alkanes via C−H activation of terminal methyl groups has acquired tremendous interests both scientifically and technically. Herein we…”
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14
Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis
Published in The Journal of experimental medicine (02-06-2014)“…Pneumonia is a major cause of mortality worldwide and a serious problem in critical care medicine, but the immunophysiological processes that confer either…”
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Fusobacterium nucleatum induces proliferation and migration in pancreatic cancer cells through host autocrine and paracrine signaling
Published in Science signaling (18-10-2022)“…The tumor microbiome is increasingly implicated in cancer progression and resistance to chemotherapy. In pancreatic ductal adenocarcinoma (PDAC), high…”
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A somatic piRNA pathway in the Drosophila fat body ensures metabolic homeostasis and normal lifespan
Published in Nature communications (21-12-2016)“…In gonadal tissues, the Piwi-interacting (piRNA) pathway preserves genomic integrity by employing 23–29 nucleotide (nt) small RNAs complexed with argonaute…”
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Combination CTLA4Ig and Anti-CD40 Ligand Treatment Modifies T and B Cell Metabolic Profiles and Promotes B Cell Receptor Remodeling in a Mouse Model of Systemic Lupus Erythematosus
Published in The Journal of immunology (1950) (01-03-2023)“…Systemic lupus erythematosus is a complex autoimmune disease with significant morbidity that demands further examination of tolerance-inducing treatments…”
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Human B-1 cells are important contributors to the naturally-occurring IgM pool against the tumor-associated ganglioside Neu5GcGM3
Published in Frontiers in immunology (30-11-2022)“…Only few studies have described the anti-tumor properties of natural antibodies (NAbs). In particular, natural IgM have been linked to cancer…”
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Female Sex Hormones Activate Human Endogenous Retrovirus Type K Through the OCT4 Transcription Factor in T47D Breast Cancer Cells
Published in AIDS research and human retroviruses (01-03-2019)“…Female sex hormones, the octamer-binding transcription factor 4 (OCT4), and human endogenous retroviruses (HERVs) are all involved in the development of breast…”
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Advanced Electrolyte Formula for Robust Operation of Vanadium Redox Flow Batteries at Elevated Temperatures
Published in Small (Weinheim an der Bergstrasse, Germany) (01-07-2024)“…Insufficient thermal stability of vanadium redox flow battery (VRFB) electrolytes at elevated temperatures (>40 °C) remains a challenge in the development and…”
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