Search Results - "Talwar, Shefali"

Decreased vascular smooth muscle contractility in Hutchinson–Gilford Progeria Syndrome linked to defective smooth muscle myosin heavy chain expression by von Kleeck, Ryan, Castagnino, Paola, Roberts, Emilia, Talwar, Shefali, Ferrari, Giovanni, Assoian, Richard K.

“…Children with Hutchinson–Gilford Progeria Syndrome (HGPS) suffer from multiple cardiovascular pathologies due to the expression of progerin, a mutant form of…”
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Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility by Shutova, Maria S, Asokan, Sreeja B, Talwar, Shefali, Assoian, Richard K, Bear, James E, Svitkina, Tatyana M

“…Nonmuscle myosin II (NMII) is uniquely responsible for cell contractility and thus defines multiple aspects of cell behavior. To generate contraction, NMII…”
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Mechanosensitive smooth muscle cell phenotypic plasticity emerging from a null state and the balance between Rac and Rho by Talwar, Shefali, Kant, Aayush, Xu, Tina, Shenoy, Vivek B., Assoian, Richard K.

“…Reversible differentiation of vascular smooth muscle cells (VSMCs) plays a critical role in vascular biology and disease. Changes in VSMC differentiation…”
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Spatio-Temporal Plasticity in Chromatin Organization in Mouse Cell Differentiation and during Drosophila Embryogenesis by Bhattacharya, Dipanjan, Talwar, Shefali, Mazumder, Aprotim, Shivashankar, G.V.

“…Cellular differentiation and developmental programs require changing patterns of gene expression. Recent experiments have revealed that chromatin organization…”
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Correlated Spatio-Temporal Fluctuations in Chromatin Compaction States Characterize Stem Cells by Talwar, Shefali, Kumar, Abhishek, Rao, Madan, Menon, Gautam I., Shivashankar, G.V.

“…Stem cells integrate signals from the microenvironment to generate lineage-specific gene expression programs upon differentiation. Undifferentiated cell nuclei…”
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Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells by Fiuza, Carmen, Bustin, Michael, Talwar, Shefali, Tropea, Margaret, Gerstenberger, Eric, Shelhamer, James H., Suffredini, Anthony F.

“…Systemic inflammation because of sepsis results in endothelial cell activation and microvascular injury. High-mobility group protein-1 (HMGB1), a novel…”
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Developmental heterogeneity in DNA packaging patterns influences T-cell activation and transmigration by Gupta, Soumya, Marcel, Nimi, Talwar, Shefali, Garg, Megha, R, Indulaxmi, Perumalsamy, Lakshmi R, Sarin, Apurva, Shivashankar, G V

“…Cellular differentiation programs are accompanied by large-scale changes in nuclear organization and gene expression. In this context, accompanying transitions…”
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Gene expression profiles of peripheral blood leukocytes after endotoxin challenge in humans by Talwar, Shefali, Munson, Peter J, Barb, Jennifer, Fiuza, Carmen, Cintron, Anadel Pilar, Logun, Carolea, Tropea, Margaret, Khan, Sameena, Reda, Debra, Shelhamer, James H, Danner, Robert L, Suffredini, Anthony F

“…1 Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 2 Mathematics and Statistical Computing Laboratory,…”
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Structural Transitions in Higher Order Chromatin Assembly and Nuclear Plasticity during Stem Cell Differentiation by Talwar, Shefali, Shivashankar, G.V.

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The regulation of gene expression during onset of differentiation by nuclear mechanical heterogeneity by Talwar, Shefali, Jain, Nikhil, Shivashankar, G.V

“…Abstract Embryonic stem (ES) cells exhibit plasticity in nuclear organization as well as variability in gene expression. Although such physicochemical features…”
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Coupling between chromosome intermingling and gene regulation during cellular differentiation by Wang, Yejun, Jain, Nikhil, Nagarajan, Mallika, Maharana, Shovamayee, Iyer, K. Venkatesan, Talwar, Shefali, Shivashankar, G.V.

“…•Nuclear morphology was stabilized with increased stiffness during differentiation.•Size-dependent radial positioning of chromosomes was established during…”
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Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease by Jison, Maria L., Munson, Peter J., Barb, Jennifer J., Suffredini, Anthony F., Talwar, Shefali, Logun, Carolea, Raghavachari, Nalini, Beigel, John H., Shelhamer, James H., Danner, Robert L., Gladwin, Mark T.

“…In sickle cell disease, deoxygenation of intra-erythrocytic hemoglobin S leads to hemoglobin polymerization, erythrocyte rigidity, hemolysis, and microvascular…”
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Dynamic Organization of Chromatin Assembly and Transcription Factories in Living Cells by Sinha, Bidisha, Bhattacharya, Dipanjan, Sinha, Deepak Kumar, Talwar, Shefali, Maharana, Shovamayee, Gupta, Soumya, Shivashankar, G.V.

“…The interphase nucleus is an active organelle involved in processing genetic information. In higher order eukaryotes, information control is compartmentalized…”
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