Search Results - "Talukder, Amjad H."
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HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes
Published in Nature communications (06-09-2017)“…T-cell-based immunotherapies are promising treatments for cancer patients. Although durable responses can be achieved in some patients, many patients fail to…”
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The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression
Published in Clinical cancer research (15-07-2018)“…Cancer immunotherapy has shown promising clinical outcomes in many patients. However, some patients still fail to respond, and new strategies are needed to…”
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Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes
Published in Frontiers in oncology (07-06-2024)“…Vestigial-like 1 (VGLL1) is a co-transcriptional activator that binds to TEA domain-containing transcription factors (TEADs). Its expression is upregulated in…”
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Evolution of CD8+ T Cell Receptor (TCR) Engineered Therapies for the Treatment of Cancer
Published in Cells (Basel, Switzerland) (10-09-2021)“…Engineered T cell receptor T (TCR-T) cell therapy has facilitated the generation of increasingly reliable tumor antigen-specific adaptable cellular products…”
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Phospholipid Scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells
Published in Cell research (01-07-2012)“…Toll-like receptor 9 (TLR9) senses microbial DNA in the endosomes of plasmacytoid dendritic cells (pDCs) and triggers MyD88-dependent type I interferon (IFN)…”
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Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1
Published in Proceedings of the National Academy of Sciences - PNAS (03-04-2007)“…Transcription, splicing, and translation are potentially coordinately regulatable in a temporospatial-dependent manner, although supporting experimental…”
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Phosphorylation-dependent regulation of nuclear localization and functions of integrin-linked kinase
Published in Proceedings of the National Academy of Sciences - PNAS (17-04-2007)“…Integrin-linked kinase (ILK) is a phosphorylated protein that regulates physiological processes that overlap with those regulated by p21-activated kinase 1…”
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MTA1, a Transcriptional Activator of Breast Cancer Amplified Sequence 3
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2006)“…Here we define a function of metastasis-associated protein 1 (MTA1), a presumed corepressor of estrogen receptor α(ERα), as a transcriptional activator of…”
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Repression of Six3 by a corepressor regulates rhodopsin expression
Published in Proceedings of the National Academy of Sciences - PNAS (07-08-2007)“…Here, we provide gain-of-function, loss-of function, and molecular evidence supporting genetic interactions between metastasis associated protein 1 (MTA1) and…”
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Metastasis-associated protein 1 deregulation causes inappropriate mammary gland development and tumorigenesis
Published in Development (Cambridge) (01-07-2004)“…Emerging data suggest that metastasis-associated protein 1 (MTA1) represses ligand-dependent transactivation functions of estrogen receptor-alpha in cultured…”
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Essential Role of KIBRA in Co-activator Function of Dynein Light Chain 1 in Mammalian Cells
Published in The Journal of biological chemistry (14-07-2006)“…Recently dynein light chain 1 (DLC1), a cytoskeleton signaling component, has been shown to interact with and transactivate estrogen receptor-α (ER), leading…”
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Metastasis-Associated Protein 1 Interacts with NRIF3, an Estrogen-Inducible Nuclear Receptor Coregulator
Published in Molecular and Cellular Biology (01-08-2004)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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MTA1 Interacts with MAT1, a Cyclin-dependent Kinase-activating Kinase Complex Ring Finger Factor, and Regulates Estrogen Receptor Transactivation Functions
Published in The Journal of biological chemistry (28-03-2003)“…The transcriptional activity of estrogen receptor-α is controlled by coregulators. MTA1 ( m e t astasis- a ssociated protein 1 ) represses estrogen…”
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Growth Factor Regulation of a 26S Proteasomal Subunit in Breast Cancer
Published in Clinical cancer research (15-04-2005)“…Purpose: We sought to gain insight into the mechanisms of heregulin-β1 (HRG) action on breast epithelial cells by identifying and characterizing HRG-regulated…”
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Grancalcin (GCA) modulates Toll‐like receptor 9 (TLR9) mediated signaling through its direct interaction with TLR9
Published in European journal of immunology (01-03-2016)“…Toll‐like receptors (TLRs) are playing important roles in stimulating the innate immune response and intensifying adaptive immune response against invading…”
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Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers
Published in Nature communications (21-10-2020)“…Cytotoxic T lymphocyte (CTL)-based cancer immunotherapies have shown great promise for inducing clinical regressions by targeting tumor-associated antigens…”
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Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations
Published in Journal for immunotherapy of cancer (01-07-2021)“…BackgroundNeoantigen (NeoAg) peptides displayed at the tumor cell surface by human leukocyte antigen molecules show exquisite tumor specificity and can elicit…”
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Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway
Published in Genes & development (01-11-2006)“…Here we show that expression of MTA3 inhibits ductal branching in virgin and pregnant murine transgenic mammary glands. MTA3 also suppresses the Wnt4 pathway…”
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Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target
Published in Leukemia (01-01-2017)Get full text
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Antihuman Epidermal Growth Factor Receptor 2 Antibody Herceptin Inhibits Autocrine Motility Factor (AMF) Expression and Potentiates Antitumor Effects of AMF Inhibitors
Published in Clinical cancer research (01-10-2002)“…Overexpression of the human epidermal growth factor receptor (HER) 2 has been linked to the development and maintenance of malignant phenotypes in breast…”
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