Search Results - "Talmadge, JE"

Rapid immunologic reconstitution following transplantation with mobilized peripheral blood stem cells as compared to bone marrow by TALMADGE, J. E, REED, E, INO, K, KESSINGER, A, KUSZYNSKI, C, HEIMANN, D, VARNEY, M, JACKSON, J, VOSE, J. M, BIERMAN, P. J

“…A majority of patients with intermediate or high-grade non-Hodgkin's lymphoma (NHL) who are treated with high-dose chemotherapy (HDT) and hematopoietic stem…”
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GM-CSF-mobilized peripheral blood CD34+ cells differ from steady-state bone marrow CD34+ cells in adhesion molecule expression by WATANABE, T, DAVE, B, HEIMANN, D. G, LETHABY, E, KESSINGER, A, TALMADGE, J. E

“…To determine the effect of growth factor mobilization on the expression of adhesion molecules, we compared CD34+ progenitor cell (PC) populations from…”
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Restoration of T and NK cell function in GM-CSF mobilized stem cell products from breast cancer patients by monocyte depletion by AGEITOS, A. G, INO, K, OZEROL, I, TARANTOLO, S, HEIMANN, D. G, TALMADGE, J. E

“…Rapid immune reconstitution is observed following autologous peripheral blood stem cell transplantation (PSCT) as compared to autologous bone marrow…”
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Down-regulation of vascular endothelial cell growth factor-C expression using small interfering RNA vectors in mammary tumors inhibits tumor lymphangiogenesis and spontaneous metastasis and enhances survival by ZHENGTANG CHEN, VARNEY, Michelle L, BACKORA, Matthew W, COWAN, Kenneth, SOLHEIM, Joyce C, TALMADGE, James E, SINGH, Rakesh K

“…Tumor production of vascular endothelial cell growth factor (VEGF)-C is associated with tumor lymphangiogenesis and lymph node metastasis. In this study, we…”
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Lenalidomide and cyclophosphamide immunoregulation in patients with metastatic, castration-resistant prostate cancer by Wang, J., McGuire, T. R., Britton, H. C., Schwarz, J. K., Loberiza, F. R., Meza, J. L., Talmadge, J. E.

“…Lenalidomide (LEN) and metronomic cyclophosphamide (CTX) regulate angiogenesis and immunosuppressive cells linked to the progression of metastatic…”
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Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice by Bibby, David C., Talmadge, James E., Dalal, Milind K., Kurz, Scott G., Chytil, Kevin M., Barry, Stephen E., Shand, David G., Steiert, Matthias

“…We report the biodistribution and pharmacokinetics (PK) of a cyclic RGD-doxorubicin-nanoparticle (NP) formulation in tumor-bearing mice. The NP core was…”
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Immunoregulatory cytokines in bone marrow and peripheral blood stem cell products by SINGH, R. K, INO, K, VARNEY, M. L, HEIMANN, D. G, TALMADGE, J. E

“…In these studies, we compared the phenotype, function, and expression of type 1, type 2, and monocyte-associated cytokine mRNA transcripts in autologous bone…”
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Cryopreservation of adenovirus-transfected dendritic cells (DCs) for clinical use by Gülen, D., Maas, S., Julius, H., Warkentin, P., Britton, H., Younos, I., Senesac, J., Pirruccello, Samuel M., Talmadge, J.E.

“…In this study, we examined the effects of cryoprotectant, freezing and thawing, and adenovirus (Adv) transduction on the viability, transgene expression,…”
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Flt-3 Ligand Reverses Late Allergic Response and Airway Hyper-Responsiveness in a Mouse Model of Allergic Inflammation by Edwan, Jehad H, Perry, Greg, Talmadge, James E, Agrawal, Devendra K

“…Flt3 ligand (Flt3-L) is a growth factor for dendritic cells and induces type 1 T cell responses. We recently reported that Flt3-L prevented OVA-induced…”
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CCL21 induces extensive intratumoral immune cell infiltration and specific anti-tumor cellular immunity by TURNQUIST, Heth R, XUEDE LIN, ASHOURI, Abdelkader E, HOLLINGSWORTH, Michael A, SINGH, Rakesh K, TALMADGE, James E, SOLHEIM, Joyce C

“…Chemokines are vital messengers that regulate immune cell activity. The chemokine CCL21 is normally expressed in secondary lymphoid organs and acts as a…”
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Pharmacokinetics of bestatin and oral activity for treatment of experimental metastases by ABE, F, ALVORD, G, KOYAMA, M, MATSUDA, A, TALMADGE, J. E

“…Bestatin is a low molecular weight aminopeptidase inhibitor originally isolated from culture filtrates of Streptomyces olivoreticuli. The serum…”
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Hematopoietic stem cell graft manipulation as a mechanism of immunotherapy by Talmadge, James E.

“…Hematopoietic stem cell transplants (SCT) are used in the treatment of neoplastic diseases, in addition to congenital, autoimmune, and inflammatory disorders…”
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Donor immune reconstitution after liver–small bowel transplantation for multiple intestinal atresia with immunodeficiency by Gilroy, Richard K., Coccia, Peter F., Talmadge, James E., Hatcher, Lori I., Pirruccello, Samuel J., Shaw, Byers W., Rubocki, Ronald J., Sudan, Debra L., Langnas, Alan N., Horslen, Simon P.

“…The syndrome of multiple intestinal atresia with immunodeficiency is a rare, invariably fatal congenital disorder. At 16 months of age, a child with this…”
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Flt3 ligand and granulocyte-macrophage colony-stimulating factor preferentially expand and stimulate different dendritic and T-cell subsets by Parajuli, Prahlad, Mosley, R.Lee, Pisarev, Vladimir, Chavez, Jennifer, Ulrich, Amy, Varney, Michelle, Singh, Rakesh K, Talmadge, James E

“…Mechanisms of T-cell stimulation by Flt3 ligand (Flt3L) and granulocyte-macrophage colony-stimulating factor (GM-CSF) remain unclear. Herein, we compared the…”
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Use of Matrix Metalloproteinase (MMP)‐9 Knockout Mice Demonstrates that MMP‐9 Activity Is not Absolutely Required for G‐CSF or Flt‐3 Ligand‐Induced Hematopoietic Progenitor Cell Mobilization or Engraftment by Robinson, Simon N., Pisarev, Vladimir M., Chavez, Jennifer M., Singh, Rakesh K., Talmadge, James E.

“…Recombinant growth factors (GFs) are used to mobilize hematopoietic stem cells (HSCs) for autologous and allogeneic transplantation; however, little is known…”
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Prolonged effect of Flt3-L plasmid to protect against allergic airway inflammation and airway hyperresponsiveness by Edwan, J.H., Talmadge, J.E., Agrawal, D.K.

“…Allergic airway inflammation was established in Balb/c mice by sensitization and challenge with ovalbumin (OVA), pUMVC3-hFLex or pUMVC3 were administered by…”
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Pharmacodynamic aspects of peptide administration biological response modifiers by Talmadge, James E

“…Cytokines, growth factors and other recombinant proteins have been one of the most rapidly growing areas of pharmaceuticals. Further, the development of these…”
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Immunization with wild-type p53 gene sequences coadministered with Flt3 ligand induces an antigen-specific type 1 T-cell response by PARAJULI, Prahlad, PISAREV, Vladimir, SUBLET, Jennifer, STEFFEL, Amy, VARNEY, Michelle, SINGH, Rakesh, LAFACE, Drake, TALMADGE, James E

“…We examined the ability of immunization with sequential adenovirus/plasmid DNA vectors expressing human wild-type p53 to stimulate a type 1 T-cell response and…”
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Monocyte/macrophage recruitment, activation and differentiation modulate interleukin-8 production: a paracrine role of tumor-associated macrophages in tumor angiogenesis by Varney, Michelle L, Olsen, Kimberlee J, Mosley, R Lee, Bucana, Corazan D, Talmadge, James E, Singh, Rakesh K

“…Tumor-associated macrophages (TAM) have been shown to play an important role in tumor angiogenesis. The purpose of this study was to determine whether monocyte…”
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Regional, but not systemic recruitment/expansion of dendritic cells by a pluronic-formulated Flt3-ligand plasmid with vaccine adjuvant activity by Sang, Hongxun, Pisarev, Vladimir M., Munger, Corey, Robinson, Simon, Chavez, Jennifer, Hatcher, Lori, Parajuli, Prahlad, Guo, Yajun, Talmadge, James E.

“…Regional recruitment of dendritic cells (DCs) by the local administration of granulocyte macrophage-colony stimulating factor (GM-CSF) or Flt3-ligand (Flt3L)…”
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