Search Results - "Talks, James"
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Delayed follow-up of medical retina patients due to COVID-19: impact on disease activity and visual acuity
Published in Graefe's archive for clinical and experimental ophthalmology (01-07-2021)“…Purpose The coronavirus pandemic has prompted unprecedented delays to treatment with anti-VEGF intravitreal injections due to the need to reduce hospital…”
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Should we still be performing macular laser for non-centre involving diabetic macular oedema? No
Published in Eye (London) (01-03-2022)Get full text
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First-Year Visual Acuity Outcomes of Providing Aflibercept According to the VIEW Study Protocol for Age-Related Macular Degeneration
Published in Ophthalmology (Rochester, Minn.) (01-02-2016)“…Purpose Aflibercept has the potential advantage of reducing capacity problems by allowing 2 monthly visits for patients with neovascular macular degeneration…”
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Macula service evaluation and assessing priorities for anti-VEGF treatment in the light of COVID-19
Published in Graefe's archive for clinical and experimental ophthalmology (01-12-2020)“…Purpose To assess the treatment position of all patients who have had an anti-VEGF injection in 2020, prior to the UK lockdown on 23 March. To assess methods…”
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Evolution of treatment paradigms in neovascular age-related macular degeneration: a review of real-world evidence
Published in British journal of ophthalmology (01-11-2021)“…The aim of this work was to evaluate the contribution of real-world evidence (RWE) in changing anti-vascular endothelial growth factor (VEGF) therapy treatment…”
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Fluid as a critical biomarker in neovascular age-related macular degeneration management: literature review and consensus recommendations
Published in Eye (London) (01-08-2021)“…Current guidelines on the management of patients with neovascular age-related macular degeneration (nAMD) lack clear recommendations on the interpretation of…”
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Anti-vascular endothelial growth factor in neovascular age-related macular degeneration - a systematic review of the impact of anti-VEGF on patient outcomes and healthcare systems
Published in BMC ophthalmology (17-07-2020)“…Systematically review the evidence describing the impact of anti-vascular endothelial growth factor (anti-VEGF) therapy on neovascular age-related macular…”
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Multiple Evanescent White Dot Syndrome and Choroidal Neovascularization following SARS-COV-2 Infection in a Patient on Dabrafenib and Trametinib
Published in Ocular immunology and inflammation (16-03-2023)“…to describe multimodal imaging and electrophysiology of multiple evanescent white dot syndrome (MEWDS) concomitant with COVID-19 infection in a patient on BRAF…”
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Stakeholder Perspectives of Clinical Artificial Intelligence Implementation: Systematic Review of Qualitative Evidence
Published in Journal of medical Internet research (10-01-2023)“…The rhetoric surrounding clinical artificial intelligence (AI) often exaggerates its effect on real-world care. Limited understanding of the factors that…”
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Sickle Eye Project: a cross-sectional, non-interventional study of the prevalence of visual impairment due to sickle cell retinopathy and maculopathy in the UK
Published in BMJ open (28-02-2024)“…IntroductionSickle cell disease (SCD) is one of the most common genetic disorders in the UK, with over 15 000 people affected. Proliferative sickle cell…”
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Real-world data in retinal diseases treated with anti-vascular endothelial growth factor (anti-VEGF) therapy - a systematic approach to identify and characterize data sources
Published in BMC ophthalmology (16-10-2019)“…Real-world data (RWD) has been a valuable addition to the scientific literature regarding treatment pathways, clinical outcomes and characteristics of patients…”
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Real-World Visual and Neovascularisation Outcomes from anti-VEGF in Central Retinal Vein Occlusion
Published in Ophthalmic epidemiology (02-01-2021)“…Central retinal vein occlusion (CRVO) can be complicated by macular oedema, requiring intravitreal injection (IVI) of anti-vascular endothelial growth factor…”
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Randomised trial of wide-field guided PRP for diabetic macular oedema treated with ranibizumab
Published in Eye (London) (01-06-2019)“…Background Diabetic macular oedema (DMO) is effectively treated with ranibizumab but multiple injections are required. Where there is also peripheral…”
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The use of real-world evidence for evaluating anti–vascular endothelial growth factor treatment of neovascular age-related macular degeneration
Published in Survey of ophthalmology (01-09-2019)“…Randomized controlled trials are the gold standard in medical research, providing evidence of the efficacy of a treatment in well-defined patient populations…”
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Safety and efficacy of an artificial intelligence-enabled decision tool for treatment decisions in neovascular age-related macular degeneration and an exploration of clinical pathway integration and implementation: protocol for a multi-methods validation study
Published in BMJ open (01-02-2023)“…IntroductionNeovascular age-related macular degeneration (nAMD) management is one of the largest single-disease contributors to hospital outpatient…”
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Comment on: Clinical outcomes in Caucasian patients with polypoidal choroidal vasculopathy
Published in Eye (London) (01-07-2019)Get full text
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Measuring the benefit of 4 years of intravitreal ranibizumab treatment for neovascular age-related macular degeneration
Published in British journal of ophthalmology (01-12-2012)“…To analyse the benefit of intravitreal ranibizumab over 4 years for patients with neovascular age-related macular degeneration (AMD). A retrospective case note…”
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A novel tool to assess the quality of RWE to guide the management of retinal disease
Published in Acta ophthalmologica (Oxford, England) (01-09-2021)“…Despite the growing importance of real‐world evidence (RWE) for guiding clinical decisions in retinal disease, there is currently no widely used guidance…”
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Developing an Evidence-Based Surgical Curriculum: Learning from a Randomized Controlled Trial of Surgical Rehearsal in Virtual Reality
Published in Journal of International Advanced Otology (01-01-2023)“…Surgical rehearsal - patient-specific preoperative surgical practice - can be provided by virtual reality simulation. This study investigated the effect of…”
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Stakeholder Perspectives on Clinical Decision Support Tools to Inform Clinical Artificial Intelligence Implementation: Protocol for a Framework Synthesis for Qualitative Evidence
Published in JMIR research protocols (01-04-2022)“…Quantitative systematic reviews have identified clinical artificial intelligence (AI)-enabled tools with adequate performance for real-world implementation. To…”
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