Search Results - "Talje, Lama"

Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate by Trofimova, Daria, Paydar, Mohammadjavad, Zara, Anthony, Talje, Lama, Kwok, Benjamin H., Allingham, John S.

“…Kinesin-13 proteins are major microtubule (MT) regulatory factors that catalyze removal of tubulin subunits from MT ends. The class-specific “neck” and loop 2…”
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Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells by Orr, Bernardo, Talje, Lama, Liu, Zhexian, Kwok, Benjamin H., Compton, Duane A.

“…Karyotype diversity is a hallmark of solid tumors that contributes to intratumor heterogeneity. This diversity is generated by persistent chromosome…”
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The actin-binding ERM protein Moesin binds to and stabilizes microtubules at the cell cortex by Solinet, Sara, Mahmud, Kazi, Stewman, Shannon F, Ben El Kadhi, Khaled, Decelle, Barbara, Talje, Lama, Ma, Ao, Kwok, Benjamin H, Carreno, Sébastien

“…Ezrin, Radixin, and Moesin (ERM) proteins play important roles in many cellular processes including cell division. Recent studies have highlighted the…”
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KIF14 Binds Tightly to Microtubules and Adopts a Rigor-Like Conformation by Arora, Kritica, Talje, Lama, Asenjo, Ana B., Andersen, Parker, Atchia, Kaleem, Joshi, Monika, Sosa, Hernando, Allingham, John S., Kwok, Benjamin H.

“…The mitotic kinesin motor protein KIF14 is essential for cytokinesis during cell division and has been implicated in cerebral development and a variety of…”
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Interdomain allosteric regulation of Polo kinase by Aurora B and Map205 is required for cytokinesis by Kachaner, David, Pinson, Xavier, El Kadhi, Khaled Ben, Normandin, Karine, Talje, Lama, Lavoie, Hugo, Lépine, Guillaume, Carréno, Sébastien, Kwok, Benjamin H, Hickson, Gilles R, Archambault, Vincent

“…Drosophila melanogaster Polo and its human orthologue Polo-like kinase 1 fulfill essential roles during cell division. Members of the Polo-like kinase (Plk)…”
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DHTP is an allosteric inhibitor of the kinesin‐13 family of microtubule depolymerases by Talje, Lama, El Kadhi, Khaled Ben, Atchia, Kaleem, Tremblay‐Boudreault, Thierry, Carreno, Sébastien, Kwok, Benjamin H.

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DHTP is an allosteric inhibitor of the kinesin-13 family of microtubule depolymerases by Talje, Lama, Ben El Kadhi, Khaled, Atchia, Kaleem, Tremblay-Boudreault, Thierry, Carreno, Sébastien, Kwok, Benjamin H.

“…•An ATPase-based high-throughput screen identified a kinesin-13 inhibitor DHTP.•DHTP inhibits kinesin-13 in a non ATP-competitive manner.•DHTP is cell…”
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Structural Basis for the Recruitment of the Ser/Thr Kinase Mnk1 by the Scaffolding Proteins DAP5 and eIF4G by Talje, Lama

“…Scaffolding proteins control the localization of protein kinases. During translation, the scaffolding proteins eIF4G and DAP5 recruit the Ser/Thr kinase Mnk1…”
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