Search Results - "Talicska, Courtney"
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Plasmon-Enhanced Brightness and Photostability from Single Fluorescent Proteins Coupled to Gold Nanorods
Published in Journal of physical chemistry. C (10-07-2014)“…Single-molecule imaging pushes fluorescence microscopy beyond the diffraction limit of traditional microscopy. Such super-resolution imaging, which relies on…”
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An Automated, Highly Selective Reaction Monitoring Instrument Using Molecular Rotational Resonance Spectroscopy
Published in Precision Chemistry (26-02-2024)“…Online monitoring of chemical reactions by using analytical chemistry tools is a powerful way to maximize control over these processes. In this paper, we…”
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Synthesis of Nirmatrelvir: Development of a Scalable Cobalt-Catalyzed Cyclopropanation for Manufacture of the Bicyclic [3.1.0]Proline-Building Block
Published in Organic process research & development (15-12-2023)“…Nirmatrelvir is a potent, selective, and orally bioavailable inhibitor of SARS-CoV-2 Mpro. Herein, we report a scalable cyclopropanation to produce the…”
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Development of a Cost-Efficient Process Toward a Key Synthetic Intermediate of the EZH2 Inhibitor PF-06821497
Published in Organic process research & development (21-06-2024)“…A cost-efficient approach for the synthesis of a key intermediate of the EZH2 inhibitor PF-06821497 was identified after performing process chemistry…”
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