Search Results - "Talhouk, Rabih S."

A Signature of Four Circulating microRNAs as Potential Biomarkers for Diagnosing Early-Stage Breast Cancer by Itani, Maha M., Nassar, Farah J., Tfayli, Arafat H., Talhouk, Rabih S., Chamandi, Ghada K., Itani, Abdul Rahman S., Makoukji, Joelle, Boustany, Rose-Mary N., Hou, Lifang, Zgheib, Nathalie K., Nasr, Rihab R.

“…Breast cancer (BC) is the most predominant type of cancer among women. The aim of this study is to find new biomarkers that can help in early detection of BC,…”
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Connexins: a myriad of functions extending beyond assembly of gap junction channels by Dbouk, Hashem A, Mroue, Rana M, El-Sabban, Marwan E, Talhouk, Rabih S

“…Connexins constitute a large family of trans-membrane proteins that allow intercellular communication and the transfer of ions and small signaling molecules…”
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Endotoxin Triggers Tumor Initiation Events in Nontumorigenic Breast Epithelial Cells and Enhances Invasion-Related Phenotype in Pretumorigenic and Tumorigenic Breast Epithelial Cells by Yassine, Farah, Fostok, Sabreen F., Al Deen, Nataly Naser, Talhouk, Rabih S.

“…Inflammation is associated with the development of several cancers, including breast cancer. However, the molecular mechanisms driving breast cancer initiation…”
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Editorial: Perspectives in Primary Prevention Research for Breast Cancer: A Focus on Gene-Environment Interactions by Lelièvre, Sophie A, Bellanger, Martine, Seewaldt, Victoria, Talhouk, Rabih S, Terry, Mary Beth

“…We initiated the collaborative research program “international breast cancer & nutrition” (IBCN) in 2010 (1), responding to the increasing trends in breast…”
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Screening of selected indigenous plants of Lebanon for antimicrobial activity by Barbour, Elie K, Al Sharif, Mohammed, Sagherian, Vatche K, Habre, Adele N, Talhouk, Rabih S, Talhouk, Salma N

“…The objective of this study is to test in vitro the antimicrobial efficacy of 39 water and 39 methanol extracts derived from different parts of 27 indigenous…”
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Differential expression of hippocampal connexins after acute hypoxia in the developing brain by Zeinieh, Michele P, Talhouk, Rabih S, El-Sabban, Marwan E, Mikati, Mohamad A

“…Abstract Acute hypoxia at postnatal day (P) 10 is an accepted model of human neonatal hypoxia which results, among other consequences, in increased hippocampal…”
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ECM-induced gap junctional communication enhances mammary epithelial cell differentiation by El-Sabban, Marwan E, Sfeir, Agnel J, Daher, Myriam H, Kalaany, Nada Y, Bassam, Rola A, Talhouk, Rabih S

“…The relationship between gap junctional intercellular communication (GJIC) and mammary cell (CID-9) differentiation in vitro was explored. CID-9 cells…”
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Gap Junctions and Wnt Signaling in the Mammary Gland: a Cross-Talk? by Fostok, Sabreen F., El-Sibai, Mirvat, El-Sabban, Marwan, Talhouk, Rabih S.

“…Connexins (Cxs), the building blocks of gap junctions (GJs), exhibit spatiotemporal patterns of expression and regulate the development and differentiation of…”
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Inflammatory responses in epithelia: endotoxin-induced IL-6 secretion and iNOS/NO production are differentially regulated in mouse mammary epithelial cells by Maalouf, Samar W, Talhouk, Rabih S, Schanbacher, Floyd L

“…IL-6 is a pro-inflammatory cytokine that signals via binding to a soluble or membrane bound receptor, while nitric oxide (NO), an oxidative stress molecule,…”
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Context dependent reversion of tumor phenotype by connexin-43 expression in MDA-MB231 cells and MCF-7 cells: Role of β-catenin/connexin43 association by Talhouk, Rabih S., Fares, Mohamed-Bilal, Rahme, Gilbert J., Hariri, Hanaa H., Rayess, Tina, Dbouk, Hashem A., Bazzoun, Dana, Al-Labban, Dania, El-Sabban, Marwan E.

“…Connexins (Cx), gap junction (GJ) proteins, are regarded as tumor suppressors, and Cx43 expression is often down regulated in breast tumors. We assessed the…”
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Heterocellular interaction enhances recruitment of α and β-catenins and ZO-2 into functional gap-junction complexes and induces gap junction-dependant differentiation of mammary epithelial cells by Talhouk, Rabih S., Mroue, Rana, Mokalled, Mayssa, Abi-Mosleh, Lina, Nehme, Ralda, Ismail, Ayman, Khalil, Antoine, Zaatari, Mira, El-Sabban, Marwan E.

“…Gap junctions (GJ) are required for mammary epithelial differentiation. Using epithelial (SCp2) and myoepithelial-like (SCg6) mouse-derived mammary cells, the…”
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Gap junctional intercellular communication in hypoxia-ischemia-induced neuronal injury by Talhouk, Rabih S, Zeinieh, Michele P, Mikati, Mohamad A, El-Sabban, Marwan E

“…Brain hypoxia-ischemia is a relatively common and serious problem in neonates and in adults. Its consequences include long-term histological and behavioral…”
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Connexins: a junctional crossroad to breast cancer by El-Saghir, Jamal A, El-Habre, Elia T, El-Sabban, Marwan E, Talhouk, Rabih S

“…The mammary gland presents a valuable model for developmental studies, spanning the embryonic stage through menarche to menopause. The dynamic remodeling of…”
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Anti-Inflammatory and Cytostatic Activities of a Parthenolide-Like Sesquiterpene Lactone from Cota palaestina subsp. syriaca by Saliba, Najat A., Ghaddar, Tarek H., Al Aaraj, Lamis, Nahhas, Rana, Ajeeb, Bushra, Fares, Mohamed-Bilal, Nasr, Bilal, Talhouk, Rabih, Talhouk, Salma N.

“…A sesquiterpene lactone 1-β,10-Epoxy-6-hydroxy-1,10H-inunolide (K100) was isolated through “bioassay-guided fractionation” from Cota palaestina subsp. syriaca,…”
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Gap junctions mediate STAT5-independent β-casein expression in CID-9 mammary epithelial cells by Talhouk, Rabih S, Khalil, Antoine A, Bajjani, Rachid, Rahme, Gilbert J, El-Sabban, Marwan E

“…Crosstalk between gap junction intracellular communication (GJIC), STAT5 and OCT-1 in gap junction (GJ)-dependent β-casein expression was investigated. CID-9…”
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Coordinated Expression of Extracellular Matrix-Degrading Proteinases and Their Inhibitors Regulates Mammary Epithelial Function during Involution by Talhouk, Rabih S., Bissell, Mina J., Werb, Zena

“…Extracellular matrix (ECM) plays an important role in the maintenance of mammary epithelial differentiation in culture. We asked whether changes in mouse…”
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Anti-inflammatory properties of Salograviolide A purified from Lebanese plant Centaurea ainetensis by Al-Saghir, Jamal, Al-Ashi, Randa, Salloum, Ralph, Saliba, Najat A, Talhouk, Rabih S, Homaidan, Fadia R

“…Anti-inflammatory activities of medicinal plants have largely been attributed to their content of sesquiterpene lactones (SLs). SLs are predominantly found in…”
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Targeted Expression of Stromelysin-1 in Mammary Gland Provides Evidence for a Role of Proteinases in Branching Morphogenesis and the Requirement for an Intact Basement Membrane for Tissue-Specific Gene Expression by Sympson, Carolyn J., Talhouk, Rabih S., Alexander, Caroline M., Chin, Jennie R., Clift, Shirley M., Bissell, Mina J., Werb, Zena

“…The extracellular matrix (ECM) is an important regulator of the differentiated phenotype of mammary epithelial cells in culture. Despite the fact that…”
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Developmental expression patterns and regulation of connexins in the mouse mammary gland: expression of connexin30 in lactogenesis by Talhouk, Rabih S, Elble, Randolph C, Bassam, Rola, Daher, Mariam, Sfeir, Agnel, Mosleh, Lina Abi, El-Khoury, Hilda, Hamoui, Samar, Pauli, Bendicht U, El-Sabban, Marwan E

“…The mammary gland reaches a fully differentiated phenotype at lactation, a stage characterized by the abundant expression of beta-casein. We have investigated…”
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Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus by Fostok, Sabreen F, Ezzeddine, Rima A, Homaidan, Fadia R, Al-Saghir, Jamal A, Salloum, Ralph G, Saliba, Najat A, Talhouk, Rabih S

“…Medicinal plants represent alternative means for the treatment of several chronic diseases, including inflammation. The genus Ranunculus, a representative of…”
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