Optical Coherence Tomography of Young’s Modulus Variations in Lymphedematous Tissue Model

The paper presents the optical coherence tomography investigations of tissue swelling caused by acute and chronic inflammations including lymphedema. Since lymphedema is characterized by a higher content of proteins in the intercellular fluid, the lymphedematous tissue model is based on the differen...

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Bibliographic Details
Published in:Russian physics journal Vol. 64; no. 11; pp. 2135 - 2140
Main Authors: Lokhin, A. A., Kistenev, Yu. V., Zakharova, O. A., Sandykova, E. A., Taletskii, A. V., Pavlova, M. E.
Format: Journal Article
Language:English
Published: Cham Springer International Publishing 01-03-2022
Springer
Springer Nature B.V
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Summary:The paper presents the optical coherence tomography investigations of tissue swelling caused by acute and chronic inflammations including lymphedema. Since lymphedema is characterized by a higher content of proteins in the intercellular fluid, the lymphedematous tissue model is based on the different fluid content in the muscular tissue. It is shown that Young’s modulus of the tissue sample reduces monotonically with increasing intercellular protein fraction.
ISSN:1064-8887
1573-9228
DOI:10.1007/s11182-022-02571-y