Search Results - "Taleb, Iosif"
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Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1
Published in PloS one (23-06-2020)“…The transcriptional regulatory machinery in mitochondrial bioenergetics is complex and is still not completely understood. We previously demonstrated that the…”
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Impact of Diabetes and Glycemia on Cardiac Improvement and Adverse Events Following Mechanical Circulatory Support
Published in Journal of the American Heart Association (16-07-2024)“…Type 2 diabetes is prevalent in cardiovascular disease and contributes to excess morbidity and mortality. We sought to investigate the effect of glycemia on…”
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Exploratory analysis of myocardial function after extracorporeal cardiopulmonary resuscitation vs conventional cardiopulmonary resuscitation
Published in BMC research notes (06-03-2020)“…Ventricular unloading is associated with myocardial recovery. We sought to evaluate the association of extracorporeal cardiopulmonary resuscitation (ECPR) on…”
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Baseline QRS duration associates with cardiac recovery in patients with continuous-flow left ventricular assist device implantation
Published in American heart journal plus (01-10-2022)“…In chronic heart failure (HF) patients supported with continuous-flow left ventricular assist device (CF-LVAD), we aimed to assess the clinical association of…”
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Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart
Published in npj aging and mechanisms of disease (28-05-2021)“…It is well established that the aging heart progressively remodels towards a senescent phenotype, but alterations of cellular microstructure and their…”
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A Mechanical Bridge to Recovery as a Bridge to Discovery: Learning From Few and Applying to Many
Published in Circulation (New York, N.Y.) (22-02-2022)Get full text
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Shock Team Approach in Refractory Cardiogenic Shock Requiring Short-Term Mechanical Circulatory Support: A Proof of Concept
Published in Circulation (New York, N.Y.) (02-07-2019)Get full text
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Does Cardiac Recovery Favorably Impact Adverse Events and Outcomes of LVAD Patients?
Published in The Journal of heart and lung transplantation (01-08-2022)Get full text
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The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
Published in Cell metabolism (02-03-2021)“…The metabolic rewiring of cardiomyocytes is a widely accepted hallmark of heart failure (HF). These metabolic changes include a decrease in mitochondrial…”
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Abstract 4127071: Pulmonary Artery Catheter Utilization in Cardiogenic Shock: Clinical Characteristics and Outcomes
Published in Circulation (New York, N.Y.) (12-11-2024)“…Abstract only Background: The pulmonary artery catheter (PAC) is used for hemodynamic monitoring, but its impact on patient outcomes, especially in cardiogenic…”
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The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure
Published in Circulation (New York, N.Y.) (21-07-2020)“…Background: Significant improvements in myocardial structure and function have been reported in some patients with advanced heart failure (termed responders…”
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Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading
Published in Circulation (New York, N.Y.) (25-04-2017)“…Cardiac recovery in response to mechanical unloading by left ventricular assist devices (LVADs) has been demonstrated in subgroups of patients with chronic…”
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Complication Rates Of Temporary Mechanical Circulatory Support In Patients With Cardiogenic Shock
Published in Journal of cardiac failure (01-01-2024)“…Temporary mechanical circulatory support (tMCS) devices are increasingly used for the management of patients experiencing cardiogenic shock despite a paucity…”
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Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support
Published in Circulation (New York, N.Y.) (31-01-2023)“…Extensive evidence from single-center studies indicates that a subset of patients with chronic advanced heart failure (HF) undergoing left ventricular assist…”
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Abstract 15177: Unloading Reveals a Latent Cardiomyocyte Regeneration Potential in the Human Heart
Published in Circulation (New York, N.Y.) (07-11-2023)“…Abstract only Introduction: Cardiomyocytes in the adult human heart show a minimal regenerative capacity. Whether this regenerative capacity of human…”
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Artificial intelligence predictive analytics in heart failure: results of the pilot phase of a pragmatic randomized clinical trial
Published in Journal of the American Medical Informatics Association : JAMIA (03-04-2024)“…We conducted an implementation planning process during the pilot phase of a pragmatic trial, which tests an intervention guided by artificial intelligence (AI)…”
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Abstract 12994: Invasive Left Atrial Pressure Monitoring and Survival on Veno-Arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock
Published in Circulation (New York, N.Y.) (16-11-2021)“…IntroductionElevated left atrial pressures (LAP) are associated with worse outcomes among patients with cardiogenic shock (CS), yet there are limited data on…”
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