Search Results - "Talbott, Heather E"

Wound healing, fibroblast heterogeneity, and fibrosis by Talbott, Heather E., Mascharak, Shamik, Griffin, Michelle, Wan, Derrick C., Longaker, Michael T.

“…Fibroblasts are highly dynamic cells that play a central role in tissue repair and fibrosis. However, the mechanisms by which they contribute to both…”
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Multiplexed evaluation of mouse wound tissue using oligonucleotide barcoding with single-cell RNA sequencing by Januszyk, Michael, Griffin, Michelle, Mascharak, Shamik, Talbott, Heather E., Chen, Kellen, Henn, Dominic, Spielman, Amanda F., Parker, Jennifer B.L., Liang, Norah E., Cotterell, Asha, Guardino, Nicholas, Foster, Deshka S., Wagh, Dhananjay, Coller, John, Gurtner, Geoffrey C., Wan, Derrick C., Longaker, Michael T.

“…Despite its rapidly increased availability for the study of complex tissue, single-cell RNA sequencing remains prohibitively expensive for large studies. Here,…”
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Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing by Mascharak, Shamik, Talbott, Heather E., Januszyk, Michael, Griffin, Michelle, Chen, Kellen, Davitt, Michael F., Demeter, Janos, Henn, Dominic, Bonham, Clark A., Foster, Deshka S., Mooney, Nancie, Cheng, Ran, Jackson, Peter K., Wan, Derrick C., Gurtner, Geoffrey C., Longaker, Michael T.

“…Regeneration is the holy grail of tissue repair, but skin injury typically yields fibrotic, non-functional scars. Developing pro-regenerative therapies…”
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Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin by Foster, Deshka S., Januszyk, Michael, Delitto, Daniel, Yost, Kathryn E., Griffin, Michelle, Guo, Jason, Guardino, Nicholas, Delitto, Andrea E., Chinta, Malini, Burcham, Austin R., Nguyen, Alan T., Bauer-Rowe, Khristian E., Titan, Ashley L., Salhotra, Ankit, Jones, R. Ellen, da Silva, Oscar, Lindsay, Hunter G., Berry, Charlotte E., Chen, Kellen, Henn, Dominic, Mascharak, Shamik, Talbott, Heather E., Kim, Alexia, Nosrati, Fatemeh, Sivaraj, Dharshan, Ransom, R. Chase, Matthews, Michael, Khan, Anum, Wagh, Dhananjay, Coller, John, Gurtner, Geoffrey C., Wan, Derrick C., Wapnir, Irene L., Chang, Howard Y., Norton, Jeffrey A., Longaker, Michael T.

“…Cancer-associated fibroblasts (CAFs) are integral to the solid tumor microenvironment. CAFs were once thought to be a relatively uniform population of…”
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Allele-specific expression reveals genetic drivers of tissue regeneration in mice by Mack, Katya L., Talbott, Heather E., Griffin, Michelle F., Parker, Jennifer B.L., Guardino, Nicholas J., Spielman, Amanda F., Davitt, Michael F., Mascharak, Shamik, Downer, Mauricio, Morgan, Annah, Valencia, Caleb, Akras, Deena, Berger, Mark J., Wan, Derrick C., Fraser, Hunter B., Longaker, Michael T.

“…In adult mammals, skin wounds typically heal by scarring rather than through regeneration. In contrast, “super-healer” Murphy Roths Large (MRL) mice have the…”
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Where There Is Fat There Is Fibrosis: Elucidating the Mechanisms of Creeping Fat-Driven Stricture Formation by Bauer-Rowe, Khristian E, Kim, Alexia, Griffin, Michelle, Foster, Deshka, Guardino, Nicholas, Guo, Jason L, Talbott, Heather E, Norton, Jeffrey A, Hyun, Jeong S, Longaker, Michael T

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Inhibition of Yes-Associated Protein Promotes Skin Wound Regeneration in Large Animals by Januszyk, Michael, Talbott, Heather E, Griffin, Michelle, Guardino, Nicholas, Spielman, Amanda, Guo, Jason L, Mascharak, Shamik, Wan, Derrick C, Longaker, Michael T

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