Search Results - "Talasaz, AmirAli"

Validation of a Plasma-Based Comprehensive Cancer Genotyping Assay Utilizing Orthogonal Tissue- and Plasma-Based Methodologies by Odegaard, Justin I, Vincent, John J, Mortimer, Stefanie, Vowles, James V, Ulrich, Bryan C, Banks, Kimberly C, Fairclough, Stephen R, Zill, Oliver A, Sikora, Marcin, Mokhtari, Reza, Abdueva, Diana, Nagy, Rebecca J, Lee, Christine E, Kiedrowski, Lesli A, Paweletz, Cloud P, Eltoukhy, Helmy, Lanman, Richard B, Chudova, Darya I, Talasaz, AmirAli

“…To analytically and clinically validate a circulating cell-free tumor DNA sequencing test for comprehensive tumor genotyping and demonstrate its clinical…”
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The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 21,807 Advanced Cancer Patients by Zill, Oliver A, Banks, Kimberly C, Fairclough, Stephen R, Mortimer, Stefanie A, Vowles, James V, Mokhtari, Reza, Gandara, David R, Mack, Philip C, Odegaard, Justin I, Nagy, Rebecca J, Baca, Arthur M, Eltoukhy, Helmy, Chudova, Darya I, Lanman, Richard B, Talasaz, AmirAli

“…Cell-free DNA (cfDNA) sequencing provides a noninvasive method for obtaining actionable genomic information to guide personalized cancer treatment, but the…”
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Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer by Kim, Seung Tae, Cristescu, Razvan, Bass, Adam J., Kim, Kyoung-Mee, Odegaard, Justin I., Kim, Kyung, Liu, Xiao Qiao, Sher, Xinwei, Jung, Hun, Lee, Mijin, Lee, Sujin, Park, Se Hoon, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Lee, Hyuk, Choi, Mingew, Talasaz, AmirAli, Kang, Peter Soonmo, Cheng, Jonathan, Loboda, Andrey, Lee, Jeeyun, Kang, Won Ki

“…Clinical studies support the efficacy of programmed cell death 1 (PD-1) targeted therapy in a subset of patients with metastatic gastric cancer (mGC). With the…”
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mRNA-Seq of single prostate cancer circulating tumor cells reveals recapitulation of gene expression and pathways found in prostate cancer by Cann, Gordon M, Gulzar, Zulfiqar G, Cooper, Samantha, Li, Robin, Luo, Shujun, Tat, Mai, Stuart, Sarah, Schroth, Gary, Srinivas, Sandhya, Ronaghi, Mostafa, Brooks, James D, Talasaz, Amirali H

“…Circulating tumor cells (CTC) mediate metastatic spread of many solid tumors and enumeration of CTCs is currently used as a prognostic indicator of survival in…”
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Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing by Schwaederle, Maria, Chattopadhyay, Ranajoy, Kato, Shumei, Fanta, Paul T, Banks, Kimberly C, Choi, In Sil, Piccioni, David E, Ikeda, Sadakatsu, Talasaz, AmirAli, Lanman, Richard B, Bazhenova, Lyudmila, Kurzrock, Razelle

“…Noninvasive genomic profiling of tumors may be possible with next-generation sequencing (NGS) of blood-derived circulating tumor DNA (ctDNA), but proof of…”
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Utility of Genomic Assessment of Blood-Derived Circulating Tumor DNA (ctDNA) in Patients with Advanced Lung Adenocarcinoma by Schwaederlé, Maria C, Patel, Sandip P, Husain, Hatim, Ikeda, Megumi, Lanman, Richard B, Banks, Kimberly C, Talasaz, AmirAli, Bazhenova, Lyudmila, Kurzrock, Razelle

“…Genomic alterations in blood-derived circulating tumor DNA (ctDNA) from patients with non-small cell lung adenocarcinoma (NSCLC) were ascertained and…”
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Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non–small cell lung cancer: Analysis of over 8000 cases by Mack, Philip C., Banks, Kimberly C., Espenschied, Carin R., Burich, Rebekah A., Zill, Oliver A., Lee, Christine E., Riess, Jonathan W., Mortimer, Stefanie A., Talasaz, AmirAli, Lanman, Richard B., Gandara, David R.

“…Background Circulating cell‐free tumor DNA (ctDNA)‐based mutation profiling, if sufficiently sensitive and comprehensive, can efficiently identify genomic…”
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Validation of Microsatellite Instability Detection Using a Comprehensive Plasma-Based Genotyping Panel by Willis, Jason, Lefterova, Martina I, Artyomenko, Alexander, Kasi, Pashtoon Murtaza, Nakamura, Yoshiaki, Mody, Kabir, Catenacci, Daniel V T, Fakih, Marwan, Barbacioru, Catalin, Zhao, Jing, Sikora, Marcin, Fairclough, Stephen R, Lee, Hyuk, Kim, Kyoung-Mee, Kim, Seung Tae, Kim, Jinchul, Gavino, Danielle, Benavides, Manuel, Peled, Nir, Nguyen, Timmy, Cusnir, Mike, Eskander, Ramez N, Azzi, Georges, Yoshino, Takayuki, Banks, Kimberly C, Raymond, Victoria M, Lanman, Richard B, Chudova, Darya I, Talasaz, AmirAli, Kopetz, Scott, Lee, Jeeyun, Odegaard, Justin I

“…To analytically and clinically validate microsatellite instability (MSI) detection using cell-free DNA (cfDNA) sequencing. Pan-cancer MSI detection using…”
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Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines by Powell, Ashley A, Talasaz, Amirali H, Zhang, Haiyu, Coram, Marc A, Reddy, Anupama, Deng, Glenn, Telli, Melinda L, Advani, Ranjana H, Carlson, Robert W, Mollick, Joseph A, Sheth, Shruti, Kurian, Allison W, Ford, James M, Stockdale, Frank E, Quake, Stephen R, Pease, R Fabian, Mindrinos, Michael N, Bhanot, Gyan, Dairkee, Shanaz H, Davis, Ronald W, Jeffrey, Stefanie S

“…To improve cancer therapy, it is critical to target metastasizing cells. Circulating tumor cells (CTCs) are rare cells found in the blood of patients with…”
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Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA by Lanman, Richard B, Mortimer, Stefanie A, Zill, Oliver A, Sebisanovic, Dragan, Lopez, Rene, Blau, Sibel, Collisson, Eric A, Divers, Stephen G, Hoon, Dave S B, Kopetz, E Scott, Lee, Jeeyun, Nikolinakos, Petros G, Baca, Arthur M, Kermani, Bahram G, Eltoukhy, Helmy, Talasaz, AmirAli

“…Next-generation sequencing of cell-free circulating solid tumor DNA addresses two challenges in contemporary cancer care. First this method of massively…”
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Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device by Talasaz, AmirAli H, Powell, Ashley A, Huber, David E, Berbee, James G, Roh, Kyung-Ho, Yu, Wong, Xiao, Wenzhong, Davis, Mark M, Pease, R. Fabian, Mindrinos, Michael N, Jeffrey, Stefanie S, Davis, Ronald W

“…The enumeration of rare circulating epithelial cells (CEpCs) in the peripheral blood of metastatic cancer patients has shown promise for improved cancer…”
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Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas by Zill, Oliver A, Greene, Claire, Sebisanovic, Dragan, Siew, Lai Mun, Leng, Jim, Vu, Mary, Hendifar, Andrew E, Wang, Zhen, Atreya, Chloe E, Kelley, Robin K, Van Loon, Katherine, Ko, Andrew H, Tempero, Margaret A, Bivona, Trever G, Munster, Pamela N, Talasaz, AmirAli, Collisson, Eric A

“…Patients with pancreatic and biliary carcinomas lack personalized treatment options, in part because biopsies are often inadequate for molecular…”
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S295 Implementation of Blood-Based Colorectal Cancer Screening: Real-World Clinical Experience by Raymond, Victoria, Foster, Gail, Hong, Yanyan, Hoang, Theresa, Liu, Jiayue, Burke, Jordan, Duenwald, Sven, Chudova, Darya, Lefterova, Martina, Talasaz, AmirAli

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S184 Longitudinal Adherence Demonstrates the Value of Blood-Based Screening Compared to Current Colorectal Cancer Screening Modalities: Results From a Discrete-Event Simulation Model by Forbes, Shaun P., Donderici, Elifnur Yay, Zhang, Nicole, Sharif, Behnam, Tremblay, Gabriel, Schafer, Gregory, Raymond, Victoria, Talasaz, AmirAli, Eagle, Craig, Das, Amar K.

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Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma by Ikeda, Sadakatsu, Tsigelny, Igor F., Skjevik, Åge A., Kono, Yuko, Mendler, Michel, Kuo, Alexander, Sicklick, Jason K., Heestand, Gregory, Banks, Kimberly C., Talasaz, AmirAli, Lanman, Richard B., Lippman, Scott, Kurzrock, Razelle

“…Background Because imaging has a high sensitivity to diagnose hepatocellular carcinoma (HCC) and tissue biopsies carry risks such as bleeding, the latter are…”
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S130 Multimodal Circulating Tumor DNA (ctDNA) Blood-Based Colorectal Cancer (CRC) Screening Test Demonstrates Clinically Meaningful Sensitivity Across Multiple Clinical Parameters by Kim, Hee Cheol, Kim, Seung Tae, He, Yupeng, Sample, Paul, Raymond, Victoria, Jaimovich, Ariel, Talasaz, AmirAli, Lee, Jeeyun

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S224 Evaluating the Risk of Non-Colorectal Cancers in Individuals With a False Positive Blood-Based Colorectal Cancer Screening Test by Chung, Daniel C., Gray, Darrell M., Singh, Harminder, Issaka, Rachel B., Raymond, Victoria M., Eagle, Craig, Hu, Sylvia, Chudova, Darya, Talasaz, AmirAli, Greenson, Joel K., Sinicrope, Frank A., Gupta, Samir, Grady, William M.

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S375 Real-World Adherence to Repeat Testing for Stool-Based Non-Invasive Colorectal Cancer Screening Tests Among Individuals With Average Risk by Shaukat, Aasma, Liao, Jiemin, Saha, Jayati, Forbes, Shaun P., Watkins, Angela, Zhang, Nicole J., Raymond, Victoria M., Das, Amarendra, Eagle, Craig, Talasaz, AmirAli

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Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay by Schwaederle, Maria, Husain, Hatim, Fanta, Paul T, Piccioni, David E, Kesari, Santosh, Schwab, Richard B, Banks, Kimberly C, Lanman, Richard B, Talasaz, AmirAli, Parker, Barbara A, Kurzrock, Razelle

“…Analysis of cell-free DNA using next-generation sequencing (NGS) is a powerful tool for the detection/monitoring of alterations present in circulating tumor…”
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Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA by Kaseb, Ahmed O, Sánchez, Nora S, Sen, Shiraj, Kelley, Robin K, Tan, Benjamin, Bocobo, Andrea G, Lim, Kian H, Abdel-Wahab, Reham, Uemura, Marc, Pestana, Roberto Carmagnani, Qiao, Wei, Xiao, Lianchun, Morris, Jeffrey, Amin, Hesham M, Hassan, Manal M, Rashid, Asif, Banks, Kimberly C, Lanman, Richard B, Talasaz, AmirAli, Mills-Shaw, Kenna R, George, Bhawana, Haque, Abedul, Raghav, Kanwal P S, Wolff, Robert A, Yao, James C, Meric-Bernstam, Funda, Ikeda, Sadakatsu, Kurzrock, Razelle

“…Molecular profiling has been used to select patients for targeted therapy and determine prognosis. Noninvasive strategies are critical to hepatocellular…”
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