Search Results - "Tal, Michal C"

Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease by Pillai, Padmini S., Molony, Ryan D., Martinod, Kimberly, Dong, Huiping, Pang, Iris K., Tal, Michal C., Solis, Angel G., Bielecki, Piotr, Mohanty, Subhasis, Trentalange, Mark, Homer, Robert J., Flavell, Richard A., Wagner, Denisa D., Montgomery, Ruth R., Shaw, Albert C., Staeheli, Peter, Iwasaki, Akiko

“…Influenza A virus (IAV) causes up to half a million deaths worldwide annually, 90% of which occur in older adults. We show that IAV-infected monocytes from…”
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Overlapping conditions in Long COVID at a multisite academic center by Grach, Stephanie L., Dudenkov, Daniel V., Pollack, Beth, Fairweather, DeLisa, Aakre, Chris A., Munipalli, Bala, Croghan, Ivana T., Mueller, Michael R., Overgaard, Joshua D., Bruno, Katelyn A., Collins, Nerissa M., Li, Zhuo, Hurt, Ryan T., Tal, Michal C., Ganesh, Ravindra, Knight, Dacre T. R.

“…Background Many patients experience persistent symptoms after COVID-19, a syndrome referred to as Long COVID (LC). The goal of this study was to identify novel…”
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Mitochondrial DNA stress primes the antiviral innate immune response by West, A. Phillip, Khoury-Hanold, William, Staron, Matthew, Tal, Michal C., Pineda, Cristiana M., Lang, Sabine M., Bestwick, Megan, Duguay, Brett A., Raimundo, Nuno, MacDuff, Donna A., Kaech, Susan M., Smiley, James R., Means, Robert E., Iwasaki, Akiko, Shadel, Gerald S.

“…Mitochondrial DNA stress potentiates type I interferon responses via activation of the cGAS–STING–IRF3 pathway. Mitochondria trigger innate immunity…”
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CD47 blockade reduces the pathologic features of experimental cerebral malaria and promotes survival of hosts with Plasmodium infection by Dulgeroff, Laughing Bear Torrez, Oakley, Miranda S., Tal, Michal C., Yiu, Ying Ying, He, Joy Q., Shoham, Maia, Majam, Victoria, Okoth, Winter A., Malla, Pallavi, Kumar, Sanjai, Weissman, Irving L.

“…CD47 is an antiphagocytic “don’t eat me” signal that inhibits programmed cell removal of self. As red blood cells (RBCs) age they lose CD47 expression and…”
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Abstract PS17-06: Humanized anti-CD47 monoclonal antibody magrolimab (Hu5F9-G4) plus trastuzumab potentiates antibody-dependent cellular phagocytosis (ADCP), and cooperate to inhibit human HER2+ breast cancer (BC) xenografts growth in vivo by Upton, Rosalynd, Feng, Dongdong, Banuelos, Allison M, Biswas, Tanuka, Willingham, Stephen, Kao, Kevin S, McKenna, Kelly, Rosenthal, Benyamin, Tal, Michal C, Volkmer, Jens-Peter, Pegram, Mark D, Weissman, Irving L

“…Abstract Background: Cancer cells overexpress CD47 to evade phagocytic programmed cell removal (PrCR) by macrophages of the innate immune system. Blocking CD47…”
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Characterization of pathological IgE-mediated mast cell activation in Lyme disease by Galloway, Sarah D, Shoham, Maia, Lee, Brandon, Torrez-Dulgeroff, Laughing Bear, Irnov, Irnov, Lin, Athena, Strausz, Satu, Hansen, Paige, Blacker, Grace, Salomon-Shulman, Rachel, Potula, Hari-Hara Surya Kumar, Markovic, Maxim, Nahass, George R, Colace, Olivia, Raveh, Tal, Pollack, Beth, Sanders, Erin, Ollila, Hanna, Wagner, Christine Jacobs, Robinson, William H, Weissman, Irving L, Tal, Michal C

“…Abstract Lyme disease, caused by the bacteria Borrelia burgdorferi, is the most common and rapidly growing vector-borne infectious disease in the United States…”
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