Search Results - "Takuo Ogiharaa"

Recommended Daily Dose of Sesame Lignans Has No Influence on Oral Absorption of P-Glycoprotein Substrates in Rats by Takumi Tomonoa, Kyoma Otsukab, Kentaro Yanob, Masahiko Kanagawab, Hiroshi Arakawab, Takuo Ogiharaa

“…Sesamin (SM) and episesamin (ESM) are constituents of sesame seeds, which are used in health foods and considered to have various beneficial effects in the…”
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Evaluation system for cell-permeable CYP3A4 inhibitory activity using 1α,25-dihydroxy-vitamin D3-induced intestinal cell lines by Ueno, Toshiya, Takahashi, Saori, Nakamura, Tomoya, Tanaka, Yasuhiro, Hori, Hisako, Mizoi, Kenta, Ogihara, Takuo

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Advances in Studies of P-Glycoprotein and Its Expression Regulators by Yano, Kentaro, Tomono, Takumi, Ogihara, Takuo

“…This review deals with recent advances in studies on P-glycoprotein (P-gp) and its expression regulators, focusing especially on our own research. Firstly, we…”
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Functional Alterations of Multidrug Resistance-Associated Proteins 2 and 5, and Breast Cancer Resistance Protein upon Snail-Induced Epithelial–Mesenchymal Transition in HCC827 Cells by Yano, Kentaro, Todokoro, Itsuki, Kamioka, Hiroki, Tomono, Takumi, Ogihara, Takuo

“…Our previous report indicated that Snail-induced epithelial–mesenchymal transition (EMT) enhanced P-glycoprotein (P-gp) function and drug resistance to P-gp…”
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Directional Drug Transport through Membrane-Supported Monolayers of Human Liver-Derived Cell Lines by Mizoi, Kenta, Kobayashi, Misako, Mashimo, Arisa, Matsumoto, Eiko, Masuda, Norio, Itoh, Manabu, Ueno, Toshiya, Tachiki, Hidehisa, Ishida, Seiichi, Ogihara, Takuo

“…The aim of this work is to develop a new assay system for screening biliary excretion drugs. When monolayers of human liver-derived cell lines HepG2 and Huh-7…”
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Relationship between Physical Parameters of Various Metal Ions and Binding Affinity for Alginate by Idota, Yoko, Kogure, Yumi, Kato, Takako, Yano, Kentaro, Arakawa, Hiroshi, Miyajima, Chihiro, Kasahara, Fumiyoshi, Ogihara, Takuo

“…We investigated the relationship between the physical parameters of various metal ions, including toxic metal ions, and the binding affinity of these metal…”
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Mechanism of Suppression of Blood Glucose Level by Calcium Alginate in Rats by Idota, Yoko, Kato, Takako, Shiragami, Kazuyo, Koike, Mariko, Yokoyama, Akari, Takahashi, Hitoe, Yano, Kentaro, Ogihara, Takuo

“…Calcium alginate (Ca-Alg) is known to suppress the postprandial increase of blood glucose, and therefore may be helpful for preventing lifestyle-related…”
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Preliminary Evaluation of Three-Dimensional Primary Human Hepatocyte Culture System for Assay of Drug-Metabolizing Enzyme-Inducing Potential by Arakawa, Hiroshi, Kamioka, Hiroki, Jomura, Tomoko, Koyama, Satoshi, Idota, Yoko, Yano, Kentaro, Kojima, Hajime, Ogihara, Takuo

“…Drug-induced liver injury (DILI) is a common reason for withdrawal of candidate drugs from clinical trials, or of approved drugs from the market. DILI may be…”
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Oseltamivir (Tamiflu) Is a Substrate of Peptide Transporter 1 by OGIHARA, Takuo, KANO, Takashi, WAGATSUMA, Tamae, WADA, Sho, YABUUCHI, Hikaru, ENOMOTO, Shigeki, MORIMOTO, Kaori, SHIRASAKA, Yoshiyuki, KOBAYASHI, Shoko, TAMAI, Ikumi

“…Oseltamivir, an ester-type prodrug of the neuraminidase inhibitor [3 R ,4 R ,5 S ]-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate phosphate…”
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Randomized, Double-Blind, Crossover Clinical Trial of the Effect of Calcium Alginate in Noodles on Postprandial Blood Glucose Level by Kato, Takako, Idota, Yoko, Shiragami, Kazuyo, Koike, Mariko, Nishibori, Fumiya, Tomokane, Miho, Seki, Takahiro, Itabashi, Keiko, Hakoda, Keiko, Takahashi, Hitoe, Yano, Kentaro, Kobayashi, Tsutomu, Obara, Nobuyuki, Ogihara, Takuo

“…We conducted a prospective, randomized, double-blind, 3-group, 3-phase crossover study to evaluate the effect of calcium alginate (Ca-Alg) on the postprandial…”
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Reduction Effect of Calcium Alginate on Blood Triglyceride Levels Causing the Inhibition of Hepatic and Total Body Accumulation of Fat in Rats by Kasahara, Fumiyoshi, Kato, Takako, Idota, Yoko, Takahashi, Hitoe, Kakinuma, Chihaya, Yano, Kentaro, Arakawa, Hiroshi, Hara, Kurt, Miyajima, Chihiro, Ogihara, Takuo

“…In this study, rats were fed a high-fat diet containing calcium alginate (Ca-Alg) for 5 weeks to examine the effects of Ca-Alg on lipid metabolism including…”
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Cholesterol-Lowering Effect of Calcium Alginate in Rats by Yoko Idotaa, Yumi Kogurea, Takako Katoa, Mana Ogawab, Shoko Kobayashib, Chihaya Kakinumaa, Kentaro Yanoa, Hiroshi Arakawaa, Chihiro Miyajimac, Fumiyoshi Kasaharac, Takuo Ogiharaa

“…We examined whether calcium alginate (Ca-Alg) reduces blood cholesterol levels in rats fed a high-cholesterol diet. First, we examined taurocholate adsorption…”
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Characterization of Cesium Uptake Mediated by a Potassium Transport System of Bacteria in a Soil Conditioner by Zhang, Pengyao, Idota, Yoko, Yano, Kentaro, Negishi, Masayuki, Kawabata, Hideaki, Arakawa, Hiroshi, Morimoto, Kaori, Tsuji, Akira, Ogihara, Takuo

“…We found that bacteria in a commercial soil conditioner sold in Ishinomaki, Miyagi, exhibited concentrative and saturable cesium ion (Cs+) uptake in the…”
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Alginate Enhances Excretion and Reduces Absorption of Strontium and Cesium in Rats by Idota, Yoko, Harada, Hitomi, Tomono, Takumi, Morimoto, Kaori, Kobayashi, Shoko, Kakinuma, Chihaya, Miyajima, Chihiro, Kasahara, Fumiyoshi, Ogihara, Takuo

“…Alginate (ALA), which is an intercellular polysaccharide associated with brown algae, is used as a food additive, a health food and a medicine. Here, we first…”
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