Search Results - "Takubo, Ryoko"

Anti-pruritic effect of nemolizumab in hemodialysis patients with uremic pruritus: a phase II, randomized, double-blind, placebo-controlled clinical study by Kinugasa, Eriko, Igawa, Ken, Shimada, Hisaki, Kondo, Morihiro, Funakoshi, Satoshi, Imada, Naoki, Itami, Noritomo, Fukazawa, Naoki, Takubo, Ryoko, Kawata, Yuichi, Murota, Hiroyuki

“…Background The pathophysiology of uremic pruritus (UP), which is characterized by systemic and intractable itching, remains unclear. As interleukin (IL)-31 may…”
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Phase I study of the safety and clinical activity of the interleukin-8 inhibitor AMY109 combined with atezolizumab in patients with advanced solid cancers by Yamamoto, Noboru, Kitano, Shigehisa, Koyama, Takafumi, Ikeda, Masafumi, Mizugaki, Hidenori, Narikiyo, Takatsugu, Yamaguchi, Yuki, Ishida, Takaaki, Takubo, Ryoko, Ogami, Chika, Sekiya, Mayuko, Nakagawa, Yuki, Kuboki, Yasutoshi

“…BackgroundImmunosuppressive conditions within the tumor microenvironment (TME) can allow tumors to evade the immune system, including by hampering programmed…”
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Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization by Igawa, Tomoyuki, Ishii, Shinya, Tachibana, Tatsuhiko, Maeda, Atsuhiko, Higuchi, Yoshinobu, Shimaoka, Shin, Moriyama, Chifumi, Watanabe, Tomoyuki, Takubo, Ryoko, Doi, Yoshiaki, Wakabayashi, Tetsuya, Hayasaka, Akira, Kadono, Shoujiro, Miyazaki, Takuya, Haraya, Kenta, Sekimori, Yasuo, Kojima, Tetsuo, Nabuchi, Yoshiaki, Aso, Yoshinori, Kawabe, Yoshiki, Hattori, Kunihiro

“…For many antibodies, each antigen-binding site binds to only one antigen molecule during the antibody's lifetime in plasma. To increase the number of cycles of…”
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