Search Results - "Takeyasu, Kunio"
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The effectiveness of Japanese public funding to generate emerging topics in life science and medicine
Published in PloS one (17-08-2023)“…Understanding the effectiveness of public funds to generate emerging topics will assist policy makers in promoting innovation. In the present study, we aim to…”
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Researcher dynamics in the generation of emerging topics in life sciences and medicine
Published in Scientometrics (01-02-2022)“…Understanding the driving forces that generate emerging topics (ETs or Emerging Research Topics) will assist in the sound development of science and…”
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Single-Molecule/Cell Analyses Reveal Principles of Genome-Folding Mechanisms in the Three Domains of Life
Published in International journal of molecular sciences (14-12-2021)“…Comparative structural/molecular biology by single-molecule analyses combined with single-cell dissection, mass spectroscopy, and biochemical reconstitution…”
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Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation
Published in The Journal of biological chemistry (14-12-2012)“…Inner nuclear membrane proteins provide a structural framework for chromatin, modulating transcription beneath the nuclear envelope. Lamin B receptor (LBR) is…”
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Motion of the Ca2+‐pump captured
Published in The FEBS journal (01-09-2011)“…Studies of ion pumps, such as ATP synthetase and Ca2+‐ATPase, have a long history. The crystal structures of several kinds of ion pump have been resolved, and…”
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Cell type-specific suppression of mechanosensitive genes by audible sound stimulation
Published in PloS one (31-01-2018)“…Audible sound is a ubiquitous environmental factor in nature that transmits oscillatory compressional pressure through the substances. To investigate the…”
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Bacillus subtilis DprA Recruits RecA onto Single-stranded DNA and Mediates Annealing of Complementary Strands Coated by SsbB and SsbA
Published in The Journal of biological chemistry (02-08-2013)“…Naturally transformable bacteria recombine internalized ssDNA with a homologous resident duplex (chromosomal transformation) or complementary internalized…”
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Visualization of conformational variability in the domains of long single-stranded RNA molecules
Published in Nucleic acids research (21-08-2017)“…We demonstrate an application of atomic force microscopy (AFM) for the structural analysis of long single-stranded RNA (>1 kb), focusing on 28S ribosomal RNA…”
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Probing the stiffness of isolated nucleoli by atomic force microscopy
Published in Histochemistry and cell biology (01-04-2014)“…In eukaryotic cells, ribosome biogenesis occurs in the nucleolus, a membraneless nuclear compartment. Noticeably, the nucleolus is also involved in several…”
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Different Proteins Mediate Step-Wise Chromosome Architectures in Thermoplasma acidophilum and Pyrobaculum calidifontis
Published in Frontiers in microbiology (12-06-2020)“…Archaeal species encode a variety of distinct lineage-specific chromosomal proteins. We have previously shown that in Thermococcus kodakarensis , histone,…”
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RecA Regulation by RecU and DprA During Bacillus subtilis Natural Plasmid Transformation
Published in Frontiers in microbiology (11-07-2018)“…Natural plasmid transformation plays an important role in the dissemination of antibiotic resistance genes in bacteria. During this process, RecA physically…”
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Atomic Force Microscopy Imaging and Analysis of Prokaryotic Genome Organization
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…This protocol describes the application of atomic force microscopy for structural analysis of the prokaryotic and organellar nucleoids. It is based on a simple…”
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Probing in vivo dynamics of mitochondria and cortical actin networks using high‐speed atomic force/fluorescence microscopy
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-02-2015)“…The dynamics of the cell membrane and submembrane structures are closely linked, facilitating various cellular activities. Although cell surface research and…”
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14
An alternative beads-on-a-string chromatin architecture in Thermococcus kodakarensis
Published in EMBO reports (01-08-2013)“…We have applied chromatin sequencing technology to the euryarchaeon Thermococcus kodakarensis , which is known to possess histone‐like proteins. We detect…”
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novel nucleoid protein of Escherichia coli induced under anaerobiotic growth conditions
Published in Nucleic acids research (01-06-2010)“…A systematic search was performed for DNA-binding sequences of YgiP, an uncharacterized transcription factor of Escherichia coli, by using the Genomic SELEX. A…”
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Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4
Published in Journal of cell science (01-04-2010)“…In addition to its well-known role as a crosslinker of actin filaments at focal-adhesion sites, actinin-4 is known to be localized to the nucleus. In this…”
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Karyopherin-independent spontaneous transport of amphiphilic proteins through the nuclear pore
Published in Journal of cell science (01-11-2012)“…Highly selective nucleocytoplasmic molecular transport is critical to eukaryotic cells, which is illustrated by size-filtering diffusion and…”
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Early steps of double-strand break repair in Bacillus subtilis
Published in DNA repair (01-03-2013)“…All organisms rely on integrated networks to repair DNA double-strand breaks (DSBs) in order to preserve the integrity of the genetic information, to…”
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Fast-scanning atomic force microscopy reveals the ATP/ADP-dependent conformational changes of GroEL
Published in The EMBO journal (04-10-2006)“…In order to fold non‐native proteins, chaperonin GroEL undergoes numerous conformational changes and GroES binding in the ATP‐dependent reaction cycle. We…”
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Spatial Control of Proton Pump H,K-ATPase Docking at the Apical Membrane by Phosphorylation-coupled Ezrin-Syntaxin 3 Interaction
Published in The Journal of biological chemistry (28-11-2014)“…The digestive function of the stomach depends on acidification of the gastric lumen. Acid secretion into the lumen is triggered by activation of a…”
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