Search Results - "Takeya, Koichi"

RA‐XXV and RA‐XXVI, Bicyclic Hexapeptides from Rubia cordifolia L.: Structure, Synthesis, and Conformation by Hitotsuyanagi, Yukio, Hirai, Masahito, Odagiri, Masumi, Komine, Miho, Hasuda, Tomoyo, Fukaya, Haruhiko, Takeya, Koichi

“…Two RA‐series bicyclic hexapeptides, RA‐XXV (4) and RA‐XXVI (5), which have no N‐methyl group at Tyr‐5, were isolated from the roots of Rubia cordifolia L…”
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Garcinielliptone G from Garcinia subelliptica Induces Apoptosis in Acute Leukemia Cells by Yun, YoungSook, Shioura, Mariko, Hitotsuyanagi, Yukio, Yotsumoto, Satoshi, Takahashi, Yuji, Aoyagi, Yutaka, Kinoshita, Takeshi, Takeya, Koichi, Inoue, Hideshi

“…Cytotoxicity and apoptosis-inducing properties of compounds isolated from leaves were investigated. The hexane-soluble portion of MeOH extracts of leaves that…”
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Synthesis of 1-O-acyl- and 1-oxo-kamebanin analogues and their cytotoxic activity by Aoyagi, Yutaka, Tomita, Kaori, Kobayashi, Asumi, Nakamura, Akari, Fujii, Yuki, Yagi, Momoka, Ichimaru, Yoshimi, Ozawa, Kei, Park, Hyun-Sun, Fukaya, Haruhiko, Yano, Reiko, Hasuda, Tomoyo, Takeya, Koichi, Hitotsuyanagi, Yukio, Gui, Ming-Yu, Jin, Yong-Ri, Li, Xu-Wen

“…[Display omitted] A series of 1-O-acyl- and 1-oxo-kamebanin analogues were prepared from kamebanin, isolated from Rabdosia excisa and their cytotoxicity was…”
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Semisynthesis of Antitrypanosomal p-Quinone Analog Possesing the Komaroviquinone Pharmacophore by Aoyagi, Yutaka, Fujiwara, Koji, Takahashi, Yoshinao, Yano, Reiko, Hitotsuyanagi, Yukio, Takeya, Koichi, Aiyama, Ritsuo, Matsuzaki, Takeshi, Hashimoto, Shusuke, Nishihara-Tsukashima, Aki, Namatame, Miyuki, Ishiyama, Aki, Iwatsuki, Masato, Otoguro, Kazuhiko, Yamada, Haruki, Ōmura, Satoshi

“…A p-quinone analog having the komaroviquinone pharmacophore fused with a more conformationally flexible cycloheptane ring, was semisynthesized from natural…”
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Structures of stemona-amine B and stemona-lactams M–R by Hitotsuyanagi, Yukio, Fukaya, Haruhiko, Takeda, Erika, Matsuda, Shoko, Saishu, Yuka, Zhu, Shu, Komatsu, Katsuko, Takeya, Koichi

“…Seven new alkaloids, stemona-amine B and stemona-lactams M–R, were isolated from the roots of Stemona tuberosa. Their structures were determined by…”
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Methyl dehydroabietate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice by Yoshioka, Hiroki, Mizuno, Yuki, Yamaguchi, Tomohiro, Ichimaru, Yoshimi, Takeya, Koichi, Hitotsuyanagi, Yukio, Nonogaki, Tsunemasa, Aoyagi, Yutaka

“…The aim of this study was to investigate the therapeutic effects of methyl dehydroabietate (mDA) on adipocyte differentiation in 3T3-L1 preadipocytes and…”
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Isolation, Structure Determination, and Synthesis of Allo-RA-V and Neo-RA-V, RA-Series Bicyclic Peptides from Rubia cordifolia L by Hitotsuyanagi, Yukio, Odagiri, Masumi, Kato, Saori, Kusano, Jun-ichi, Hasuda, Tomoyo, Fukaya, Haruhiko, Takeya, Koichi

“…Two bicyclic hexapeptides, allo‐RA‐V (4) and neo‐RA‐V (5), and one cyclic hexapeptide, O‐seco‐RA‐V (6), were isolated from the roots of Rubia cordifolia L…”
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RA-dimer B, a New Dimeric RA-series Cyclopeptide Incorporating Two Different Types of Cycloisodityrosine Units, from Rubia cordifolia L by Hitotsuyanagi, Yukio, Tsuchiya, Takayuki, Ohata, Masako, Yoshida, Ayaka, Fukaya, Haruhiko, Park, Hyun Sun, Takeya, Koichi, Kawahara, Nobuo

“…RA‐dimer B, a new cytotoxic RA‐series peptide, was isolated from the roots of Rubia cordifolia L. Its structure was elucidated on the basis of spectroscopic…”
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Structures of stemoxazolidinones A–F, alkaloids from Stemona sessilifolia by Hitotsuyanagi, Yukio, Hikita, Maho, Uemura, Gou, Fukaya, Haruhiko, Takeya, Koichi

“…Six new alkaloids, stemoxazolidinones A–F, were isolated from the roots of Stemona sessilifolia (Miq.) Miq. (Stemonaceae). The structures of stemoxazolidinones…”
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Suppressive effect of kamebakaurin on acetaminophen-induced hepatotoxicity by inhibiting lipid peroxidation and inflammatory response in mice by Yoshioka, Hiroki, Aoyagi, Yutaka, Fukuishi, Nobuyuki, Gui, Ming-Yu, Jin, Yong-Ri, Li, Xu-Wen, Adachi, Yoshiyuki, Ohno, Naohito, Takeya, Koichi, Hitotsuyanagi, Yukio, Miura, Nobuhiko, Nonogaki, Tsunemasa

“…Kamebakaurin (KA) is an ent-kaurane diterpenoid known to have anti-inflammatory potential. In the current study, we investigated whether pretreatment with KA…”
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Structure and hydrogen bonds of cyclohexapeptide RA-VII by molecular dynamics simulations and quantum chemical calculations by Noguchi, Yoh, Yamada, Hironao, Mori, Sakiko, Miyakawa, Takeshi, Morikawa, Ryota, Yokojima, Satoshi, Hitotsuyanagi, Yukio, Takeya, Koichi, Takasu, Masako

“…We computationally examined the structure of anti-tumour bicyclic hexapeptide RA-VII. This peptide adopts three conformations (confs.), A, B and C, in dimethyl…”
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Absolute Structures of Stemona-Lactam S and Tuberostemospiroline, Alkaloids from Stemona tuberosa by Fukaya, Haruhiko, Hitotsuyanagi, Yukio, Aoyagi, Yutaka, Shu, Zhu, Komatsu, Katsuko, Takeya, Koichi

“…A new alkaloid, stemona-lactam S, and a known alkaloid, tuberostemospiroline, were isolated from the roots of Stemona tuberosa LOUR . (Stemonaceae). Their…”
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1O, 20O-diacetyl kamebakaurin protects against acetaminophen-induced hepatotoxicity in mice by YOSHIOKA, Hiroki, NONOGAKI, Tsunemasa, OHNISHI, Hiroyuki, FUKUISHI, Nobuyuki, YOSHIKAWA, Masae, GUI, Ming-Yu, JIN, Yong-Ri, LI, Xu-Wen, ADACHI, Yoshiyuki, OHNO, Naohito, TAKEYA, Koichi, HITOTSUYANAGI, Yukio, MIURA, Nobuhiko, AOYAGI, Yutaka

“…The present study aimed to investigate the protective effects of kamebakaurin (KA) and 1O, 20O-diacetyl kamebakaurin (Ac2KA) on acetaminophen (APAP)-induced…”
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Ceramicine A and walsogyne A, novel limonoids from two species of Meliaceae by Mohamad, Khalit, Hirasawa, Yusuke, Lim, Chong Soon, Awang, Khalijah, Hadi, A. Hamid A., Takeya, Koichi, Morita, Hiroshi

“…Two novel limonoids, ceramicine A with no methyls at C-4, and walsogyne A with a ring C- seco limonoid, have been isolated from the barks of Chisocheton…”
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Apotirucallane and Tirucallane Triterpenoids from Cedrela sinensis by Mitsui, Kumiko, Saito, Hiroaki, Yamamura, Ryota, Fukaya, Haruhiko, Hitotsuyanagi, Yukio, Takeya, Koichi

“…Nine new triterpenoids, 1—9, were isolated from the cortex of Cedrela sinensis (Meliaceae), together with six known compounds, sapelin E acetate,…”
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Bioactive Cyclic Peptides from Higher Plants by Morita, Hiroshi, Takeya, Koichi

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Structures of cytotoxic bicyclic hexapeptides, RA-XIX, -XX, -XXI, and -XXII, from Rubia cordifolia L by Lee, Ji-Ean, Hitotsuyanagi, Yukio, Takeya, Koichi

“…Novel bicyclic hexapeptides, RA-XIX, -XX, -XXI, and -XXII, were isolated from the roots of Rubia cordifolia L. The structures of RA-XIX and RA-XX were…”
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Celogentins A−C, New Antimitotic Bicyclic Peptides from the Seeds of Celosia argentea by KOBAYASHI, Jun'ichi, SUZUKI, Hayato, SHIMBO, Kazutaka, TAKEYA, Koichi, MORITA, Hiroshi

“…Three new bicyclic peptides, celogentins A (1), B (2), and C (3), have been isolated together with a known-related peptide, moroidin (4), from the seeds of…”
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Vasorelaxant activity of cyclic peptide, cyclosquamosin B, from Annona squamosa by Morita, Hiroshi, Iizuka, Toru, Choo, Chee-Yan, Chan, Kit-Lam, Takeya, Koichi, Kobayashi, Jun’ichi

“…A cyclic octapeptide, cyclosquamosin B ( 2), isolated from the seeds of Annona squamosa showed a vasorelaxant effect on rat aorta. It showed a slow relaxation…”
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Cytotoxic Bisnor- and Norditerpene Dilactones Having 7α,8α-Epoxy-9,11-enolide Substructure from Podocarpus macrophyllus D. DON by Sato, Kimihiko, Inaba, Yasunori, Park, Hyun-Sun, Akiyama, Toshiyuki, Koyama, Tetsuo, Fukaya, Haruhiko, Aoyagi, Yutaka, Takeya, Koichi

“…Fourteen new bisnor- and norditerpene dilactones, makilactones E—R, having a 7α : 8α-epoxy-9,11-enolide substructure, were isolated from a methanolic extract…”
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