Search Results - "Takeuchi, M."
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cKit⁺ cardiac progenitors of neural crest origin
Published in Proceedings of the National Academy of Sciences - PNAS (20-10-2015)“…The degree to whichcKit-expressing progenitors generate cardiomyocytes in the heart is controversial. Genetic fate-mapping studies suggest minimal…”
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Removal characteristics of pharmaceuticals and personal care products: Comparison between membrane bioreactor and various biological treatment processes
Published in Chemosphere (Oxford) (01-07-2017)“…We investigated the concentrations of 57 target compounds in the different treatment units of various biological treatment processes in South Korea, including…”
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Hydroxychloroquine Mitigates Dilated Cardiomyopathy Phenotype in Transgenic D94A Mice
Published in International journal of molecular sciences (09-12-2022)“…In this study, we aimed to investigate whether short-term and low-dose treatment with hydroxychloroquine (HCQ), an antimalarial drug, can modulate heart…”
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Evaluation of T‐cell related cytokines in the vitreous of proliferative diabetic retinopathy
Published in Acta ophthalmologica (Oxford, England) (01-10-2015)“…Summary Macrophages are involved in low‐grade inflammation in diabetes, and play pathogenic roles in proliferative diabetic retinopathy (PDR) by producing…”
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Behçet's uveitis in Japan: evaluation of the long‐term efficacy and safety of infliximab treatment
Published in Acta ophthalmologica (Oxford, England) (01-10-2015)“…Summary Retrospective 13 multicenter observational study were performed using a questionnaire of 164 Behçet's patients treated with infliximab for more than…”
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Efficacy of a growth hormone-releasing hormone agonist in a murine model of cardiometabolic heart failure with preserved ejection fraction
Published in American journal of physiology. Heart and circulatory physiology (01-06-2023)“…Heart failure (HF) with preserved ejection fraction (HFpEF) represents a major unmet medical need owing to its diverse pathophysiology and lack of effective…”
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Pirfenidone in idiopathic pulmonary fibrosis
Published in The European respiratory journal (01-04-2010)“…Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease without proven effective therapy. A multicentre, double-blind, placebo-controlled, randomised…”
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Surface preparation of metal films by gas cluster ion beams using organic acid vapor for Cu–Cu bonding
Published in Japanese Journal of Applied Physics (01-06-2022)“…Abstract Surface-activated bonding (SAB) of Cu by gas cluster ion beam (GCIB) irradiation with acetic acid vapor was studied. GCIB irradiation realizes surface…”
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Ablation of the N terminus of cardiac essential light chain promotes the super‐relaxed state of myosin and counteracts hypercontractility in hypertrophic cardiomyopathy mutant mice
Published in The FEBS journal (01-09-2020)“…In this study, we focus on the molecular mechanisms associated with the A57G (Ala57‐to‐Gly57) mutation in myosin essential light chains (ELCs), found to cause…”
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Synthetic growth hormone-releasing hormone agonist ameliorates the myocardial pathophysiology characteristic of heart failure with preserved ejection fraction
Published in Cardiovascular research (03-02-2023)“…To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signalling pathway within the myocardium both prevents and…”
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Metformin inhibits advanced glycation end products (AGEs)-induced renal tubular cell injury by suppressing reactive oxygen species generation via reducing receptor for AGEs (RAGE) expression
Published in Hormone and metabolic research (01-11-2012)“…Advanced glycation end products (AGEs) and their receptor (RAGE) play a role in tubulointerstitial damage in diabetic nephropathy. Recently, metformin has been…”
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Linagliptin blocks renal damage in type 1 diabetic rats by suppressing advanced glycation end products-receptor axis
Published in Hormone and metabolic research (01-09-2014)“…Advanced glycation end products (AGEs) and their receptor (RAGE) play a role in diabetic nephropathy. We have recently found that linagliptin, an inhibitor of…”
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Efficacy and safety of once-weekly dulaglutide in combination with sulphonylurea and/or biguanide compared with once-daily insulin glargine in Japanese patients with type 2 diabetes: a randomized, open-label, phase III, non-inferiority study
Published in Diabetes, obesity & metabolism (01-10-2015)“…Aims To evaluate 0.75 mg of dulaglutide, a once‐weekly glucagon‐like peptide‐1 receptor agonist, compared with once‐daily insulin glargine for glycaemic…”
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Analysis of astragaloside IV metabolism to cycloastragenol in human gut microorganism, bifidobacteria, and lactic acid bacteria
Published in Bioscience, biotechnology, and biochemistry (23-09-2022)“…ABSTRACT This study investigated different gut bacteria in an anaerobic environment to identify specific candidates that could transform astragaloside IV (AIV)…”
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Locking the local oscillator phase to the atomic phase via weak measurement
Published in New journal of physics (15-02-2012)“…A new method is proposed to reduce the frequency noise of a local oscillator to the level of white phase noise by maintaining (not destroying by projective…”
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Effect of surface irregularities on diamond Schottky barrier diode with threading dislocations
Published in Diamond and related materials (01-08-2022)“…Pyramidal and flat-type hillocks, both known for having a threading dislocation in the center, are utilized to examine the effect of surface irregularities on…”
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Therapeutic potential of AAV9-S15D-RLC gene delivery in humanized MYL2 mouse model of HCM
Published in Journal of molecular medicine (Berlin, Germany) (01-07-2019)“…Familial hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder characterized by ventricular hypertrophy, myofibrillar disarray, and fibrosis, and…”
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Cardioprotective effects of growth hormone-releasing hormone agonist after myocardial infarction
Published in Proceedings of the National Academy of Sciences - PNAS (09-02-2010)“…Whether the growth hormone (GH)/insulin-like growth factor 1(IGF-1) axis exerts cardioprotective effects remains controversial; and the underlying mechanism(s)…”
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Automatic surgical phase recognition in laparoscopic inguinal hernia repair with artificial intelligence
Published in Hernia : the journal of hernias and abdominal wall surgery (01-12-2022)“…Background Because of the complexity of the intra-abdominal anatomy in the posterior approach, a longer learning curve has been observed in laparoscopic…”
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