Search Results - "Takeshita, Sen"

Involvement of the Calcium-sensing Receptor in Human Taste Perception by Ohsu, Takeaki, Amino, Yusuke, Nagasaki, Hiroaki, Yamanaka, Tomohiko, Takeshita, Sen, Hatanaka, Toshihiro, Maruyama, Yutaka, Miyamura, Naohiro, Eto, Yuzuru

“…By human sensory analyses, we found that various extracellular calcium-sensing receptor (CaSR) agonists enhance sweet, salty, and umami tastes, although they…”
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Structure–activity relationship study, target identification, and pharmacological characterization of a small molecular IL-12/23 inhibitor, APY0201 by Hayakawa, Nobuhiko, Noguchi, Masatsugu, Takeshita, Sen, Eviryanti, Agung, Seki, Yukie, Nishio, Hikaru, Yokoyama, Ryohei, Noguchi, Misato, Shuto, Manami, Shima, Yoichiro, Kuribayashi, Kanna, Kageyama, Shunsuke, Eda, Hiroyuki, Suzuki, Manabu, Hatta, Tomohisa, Iemura, Shun-ichiro, Natsume, Tohru, Tanabe, Itsuya, Nakagawa, Ryusuke, Shiozaki, Makoto, Sakurai, Kuniya, Shoji, Masataka, Andou, Ayatoshi, Yamamoto, Takashi

“…Interleukin-12 (IL-12) and IL-23 are proinflammatory cytokines and therapeutic targets for inflammatory and autoimmune diseases, including inflammatory bowel…”
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Interaction Analysis of FABP4 Inhibitors by X‑ray Crystallography and Fragment Molecular Orbital Analysis by Tagami, Uno, Takahashi, Kazutoshi, Igarashi, Shunsuke, Ejima, Chieko, Yoshida, Tomomi, Takeshita, Sen, Miyanaga, Wataru, Sugiki, Masayuki, Tokumasu, Munetaka, Hatanaka, Toshihiro, Kashiwagi, Tatsuki, Ishikawa, Kohki, Miyano, Hiroshi, Mizukoshi, Toshimi

“…X-ray crystal structural determination of FABP4 in complex with four inhibitors revealed the complex binding modes, and the resulting observations led to…”
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Impact of Fab1/Vac14 inhibition on β-1,3-glucanase localization at the tip in Saccharomyces cerevisiae by Takeshita, Sen, Iida, Yasuhiro

“…Deep mycosis is a severe fungal disease that could result in fatal outcomes. However, there is still a demand for highly effective and safe antifungal drugs,…”
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Tu1864 A Novel Orally Active Phosphatidylinositol 3-Phosphate 5-Kinase (Pikfyve) Inhibitor Ameliorates Mouse Colitis by Inhibition of IL-12 and IL-23 Production From Macrophages by Andou, Ayatoshi, Yamamoto, Takashi, Agung, Eviryanti, Seki, Yukie, Nishio, Hikaru, Shuto, Manami, Noguchi, Misato, Shima, Yoichiro, Takeshita, Sen, Yokoyama, Ryohei, Hayakawa, Nobuhiko, Noguchi, Masatsugu, Kageyama, Shunsuke, Eda, Hiroyuki, Shiozaki, Makoto, Tanabe, Itsuya, Nakagawa, Ryusuke, Sakurai, Kuniya, Masataka, Shoji

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Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein by Honma, Naoyuki, Asada, Akiko, Takeshita, Sen, Enomoto, Mariko, Yamakawa, Eiko, Tsutsumi, Koji, Saito, Taro, Satoh, Takaya, Itoh, Hiroshi, Kaziro, Yoshito, Kishimoto, Takeo, Hisanaga, Shin-ichi

“…A 3 ′-terminal fragment of a splice variant of KIAA0641, a human homologue of apoptosis-associated tyrosine kinase (AATYK), was screened from human brain cDNA…”
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AJS1669, a novel small-molecule muscle glycogen synthase activator, improves glucose metabolism and reduces body fat mass in mice by Nakano, Kazuhiro, Takeshita, Sen, Kawasaki, Noriko, Miyanaga, Wataru, Okamatsu, Yoriko, Dohi, Mizuki, Nakagawa, Tadakiyo

“…Impaired glycogen synthesis and turnover are common in insulin resistance and type 2 diabetes. As glycogen synthase (GS) is a key enzyme involved in the…”
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AJS1669, a novel small-molecule muscle glycogen synthase activator, improves glucose metabolism and reduces body fat mass in mice by Nakano, Kazuhiro, Takeshita, Sen, Kawasaki, Noriko, Miyanaga, Wataru, Okamatsu, Yoriko, Dohi, Mizuki, Nakagawa, Tadakiyo

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