Search Results - "Takeshima, Kosuke"
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Redundant and Specific Roles of A-Type Lamins and Lamin B Receptor in Herpes Simplex Virus 1 Infection
Published in Journal of virology (21-12-2022)“…We investigated whether A-type lamins (lamin A/C) and lamin B receptor (LBR) are redundant during herpes simplex virus 1 (HSV-1) infection in HeLa cells…”
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Identification of the Capsid Binding Site in the Herpes Simplex Virus 1 Nuclear Egress Complex and Its Role in Viral Primary Envelopment and Replication
Published in Journal of virology (01-11-2019)“…During nuclear egress of nascent progeny herpesvirus nucleocapsids, the nucleocapsids acquire a primary envelope by budding through the inner nuclear membrane…”
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Establishment of a system to quantify wild‐type herpes simplex virus–induced cell–cell fusion reveals a role of N‐glycosylation of HSV‐1 envelope glycoprotein B in cell–cell fusion
Published in Microbiology and immunology (01-03-2023)“…Wild‐type herpes simplex virus (HSV) strains infrequently mediate cell–cell fusion in cell cultures and barely induce large multinucleated cells. In this…”
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Role of the Arginine Cluster in the Disordered Domain of Herpes Simplex Virus 1 UL34 for the Recruitment of ESCRT-III for Viral Primary Envelopment
Published in Journal of virology (26-01-2022)“…During the nuclear export of nascent nucleocapsids of herpesviruses, the nucleocapsids bud through the inner nuclear membrane (INM) by acquiring the INM as a…”
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Roles of the Interhexamer Contact Site for Hexagonal Lattice Formation of the Herpes Simplex Virus 1 Nuclear Egress Complex in Viral Primary Envelopment and Replication
Published in Journal of virology (15-07-2019)“…During the nuclear export of nascent nucleocapsids of herpes simplex virus 1 (HSV-1), the nucleocapsids acquire a primary envelope by budding through the inner…”
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Phosphoregulation of a Conserved Herpesvirus Tegument Protein by a Virally Encoded Protein Kinase in Viral Pathogenicity and Potential Linkage between Its Evolution and Viral Phylogeny
Published in Journal of virology (31-08-2020)“…Us3 proteins of herpes simplex virus 1 (HSV-1) and HSV-2 are multifunctional serine-threonine protein kinases. Here, we identified an HSV-2 tegument protein,…”
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Prohibitin-1 Contributes to Cell-to-Cell Transmission of Herpes Simplex Virus 1 via the MAPK/ERK Signaling Pathway
Published in Journal of virology (13-01-2021)“…Viral cell-to-cell spread, a method employed by several viral families for entrance via cell junctions, is highly relevant to the pathogenesis of various viral…”
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Regulation of Herpes Simplex Virus 2 Protein Kinase UL13 by Phosphorylation and Its Role in Viral Pathogenesis
Published in Journal of virology (01-09-2018)“…UL13 proteins are serine/threonine protein kinases encoded by herpes simplex virus 1 (HSV-1) and HSV-2. Although the downstream effects of the HSV protein…”
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Role of the Orphan Transporter SLC35E1 in the Nuclear Egress of Herpes Simplex Virus 1
Published in Journal of virology (25-05-2022)“…This study developed a system consisting of two rounds of screening cellular proteins involved in the nuclear egress of herpes simplex virus 1 (HSV-1). Using…”
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Dual impacts of a glycan shield on the envelope glycoprotein B of HSV-1: evasion from human antibodies in vivo and neurovirulence
Published in mBio (27-06-2023)“…Identification of the mechanisms of viral evasion from human antibodies is crucial both for understanding viral pathogenesis and for designing effective…”
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Associations of HLA-C01:02 and HLA-B46:01 with regorafenib-induced erythema multiforme in Japanese patients with metastatic colorectal cancer
Published in Clinical and translational science (01-10-2023)“…Regorafenib improves the survival of patients with metastatic colorectal cancer (mCRC); however, it is also characterized by detrimental dermal side effects…”
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Oral tolerance is inducible during active dextran sulfate sodium-induced colitis
Published in World journal of gastrointestinal pharmacology and therapeutics (06-05-2016)“…AIM:To investigate whether oral tolerance is inducible during the active phase of dextran sulfate sodium(DSS)-induced colitis.METHODS:Colitis was induced in…”
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Impact of the interaction between herpes simplex virus 1 ICP22 and FACT on viral gene expression and pathogenesis
Published in Journal of virology (20-08-2024)“…Facilitates chromatin transcription (FACT) interacts with nucleosomes to promote gene transcription by regulating the dissociation and reassembly of…”
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MYBBP1A is required for efficient replication and gene expression of herpes simplex virus 1
Published in Microbiology and immunology (01-04-2024)“…More than 100 different herpes simplex virus 1 (HSV‐1) genes belong to three major classes, and their expression is coordinately regulated and sequentially…”
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Autologous Transplantation Of Thrombopoietin Derived-Hepatic Hematopoietic Progenitor Cells In Xenopus Laevis
Published in Blood (15-11-2013)“…Thrombopoietin (TPO) is required for megakaryopoiesis generating platelets via acting through its receptor c-Mpl, and supports hematopoietic stem cell…”
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