Search Results - "Takeshi Azuma"
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Dichotomy in intrahepatic cholangiocarcinomas based on histologic similarities to hilar cholangiocarcinomas
Published in Modern pathology (01-07-2017)“…Intrahepatic cholangiocarcinomas were classified into two types based on their microscopic appearance. Tumors with histologic similarities to hilar…”
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2
Serum soluble B7-H3 is a prognostic marker for patients with non-muscle-invasive bladder cancer
Published in PloS one (11-12-2020)“…B7-H3 is a member of the B7 family of immune-regulatory ligands and is a costimulatory molecule promoting the T cell response in vitro. We herein investigated…”
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3
B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells
Published in Blood (01-04-2008)“…B7-H1 is an immunoglobulin-like immune suppressive molecule broadly detectable on the majority of human and rodent cancers, and its functions have been…”
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A novel serum metabolomics-based diagnostic approach for colorectal cancer
Published in PloS one (11-07-2012)“…To improve the quality of life of colorectal cancer patients, it is important to establish new screening methods for early diagnosis of colorectal cancer. We…”
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Serum soluble B7-H4 is a prognostic marker for patients with non-metastatic clear cell renal cell carcinoma
Published in PloS one (25-07-2018)“…B7-H4 is a member of the B7 family of immune-regulatory ligands and is considered to be a negative regulator of the immune response. We investigated the…”
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6
Utility of periodic medical questionnaires and examinations for immune-related adverse event screening: A prospective observational study
Published in PloS one (29-09-2022)“…BackgroundImmune checkpoint inhibitors (ICIs) are associated with immune-related adverse events (irAEs) specific to the immunity-boosting activity of the drugs…”
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Utility of periodic medical questionnaires and examinations for immune-related adverse event screening: A prospective observational study
Published in PloS one (29-09-2022)“…Background Immune checkpoint inhibitors (ICIs) are associated with immune-related adverse events (irAEs) specific to the immunity-boosting activity of the…”
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8
Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA
Published in Scientific reports (07-01-2016)“…CagA, encoded by cytotoxin-associated gene A ( cagA ), is a major virulence factor of Helicobacter pylori , a gastric pathogen involved in the development of…”
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Evidence-based clinical practice guidelines for irritable bowel syndrome
Published in Journal of gastroenterology (01-01-2015)“…New strategies for the care of irritable bowel syndrome (IBS) are developing and several novel treatments have been globally produced. New methods of care…”
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10
Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography–mass spectrometry
Published in Journal of gastroenterology (01-01-2012)“…Recently, metabolome analysis has been increasingly applied to biomarker detection and disease diagnosis in medical studies. Metabolome analysis is a strategy…”
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1,635 Endoscopic submucosal dissection cases in the esophagus, stomach, and colorectum: complication rates and long-term outcomes
Published in Surgical endoscopy (01-03-2013)“…Background Endoscopic submucosal dissection (ESD) enables en bloc resection of early gastrointestinal neoplasms; however, most ESD articles report small…”
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Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse
Published in Proceedings of the National Academy of Sciences - PNAS (22-01-2008)“…Infection with cagA-positive Helicobacter pylori is associated with gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma of B…”
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13
Microbial Inactivation in the Liquid Phase Induced by Multigas Plasma Jet
Published in PloS one (14-07-2015)“…Various gas atmospheric nonthermal plasmas were generated using a multigas plasma jet to treat microbial suspensions. Results indicated that carbon dioxide and…”
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14
Differences in elongation of very long chain fatty acids and fatty acid metabolism between triple-negative and hormone receptor-positive breast cancer
Published in BMC cancer (29-08-2017)“…Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological…”
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Serum alanine aminotransferase as an early marker of outcomes in patients receiving anti-PD-1 or anti-CTLA-4 antibody
Published in Scientific reports (13-05-2021)“…Immune-oncology (IO) drug therapy is effective against various types of cancer. Although several, potential, clinical predictive markers have been identified,…”
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A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer
Published in Cancer epidemiology, biomarkers & prevention (01-04-2013)“…To improve the prognosis of patients with pancreatic cancer, more accurate serum diagnostic methods are required. We used serum metabolomics as a diagnostic…”
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17
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
Published in Nature medicine (01-04-2007)“…Infection with Helicobacter pylori (H. pylori) is a risk factor for the development of gastric cancer. Here we show that infection of gastric epithelial cells…”
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Remission Depth in Metastatic Hormone-Sensitive Prostate Cancer Is Associated With Prognosis in Patients With Initial Prostate-Specific Antigen Values Above 100 Ng/ML
Published in Curēus (Palo Alto, CA) (11-02-2024)“…Recently, new drugs have caused a paradigm shift in the treatment of metastatic hormone-sensitive prostate cancer (HSPC). Meanwhile, research has identified…”
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Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity
Published in Nature (17-05-2007)“…Helicobacter pylori cagA-positive strains are associated with gastritis, ulcerations and gastric adenocarcinoma. CagA is delivered into gastric epithelial…”
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Metabolome analysis for discovering biomarkers of gastroenterological cancer
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-09-2014)“…•Introduction of metabolome analysis for biomarker discovery.•Overview of the advanced technologies used for metabolic profiling.•Utility of metabolome…”
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