Search Results - "Takemura, Ayumi"

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  1. 1
    Discovery of (1R,2S)‑2-{[(2,4-Dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)‑N‑(5-fluoropyridin-2-yl)cyclopropanecarboxamide (E2006): A Potent and Efficacious Oral Orexin Receptor Antagonist

    Discovery of (1R,2S)‑2-{[(2,4-Dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)‑N‑(5-fluoropyridin-2-yl)cyclopropanecarboxamide (E2006): A Potent and Efficacious Oral Orexin Receptor Antagonist by Yoshida, Yu, Naoe, Yoshimitsu, Terauchi, Taro, Ozaki, Fumihiro, Doko, Takashi, Takemura, Ayumi, Tanaka, Toshiaki, Sorimachi, Keiichi, Beuckmann, Carsten T, Suzuki, Michiyuki, Ueno, Takashi, Ozaki, Shunsuke, Yonaga, Masahiro

    Published in Journal of medicinal chemistry (11-06-2015)
    “…The orexin/hypocretin receptors are a family of G protein-coupled receptors and consist of orexin-1 (OX1) and orexin-2 (OX2) receptor subtypes. Orexin…”
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  2. 2
    Sphingoid base in pineapple glucosylceramide suppresses experimental allergy by binding leukocyte mono‐immunoglobulin‐like receptor 3

    Sphingoid base in pineapple glucosylceramide suppresses experimental allergy by binding leukocyte mono‐immunoglobulin‐like receptor 3 by Takemura, Ayumi, Ohto, Nobuaki, Kuwahara, Hiroshige, Mizuno, Masashi

    “…BACKGROUND The increase in patients suffering from type I hypersensitivity, including hay fever and food allergy, is a serious public health issue around the…”
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