Search Results - "Takegami, Shigehiko"

Framework-Directed Amino-Acid Insertions Generated over 55-Fold Affinity-Matured Antibody Fragments That Enabled Sensitive Luminescent Immunoassays of Cortisol by Kiguchi, Yuki, Morita, Izumi, Yamaki, Kouya, Takegami, Shigehiko, Kobayashi, Norihiro

“…We generated three single-chain Fv fragments (scFvs) specific to cortisol according to our original affinity-maturation strategy and verified their utility in…”
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Application of Molecularly Imprinted Polymer-modified Potentiometric Sensor for Quantitative Determination of Histamine in Serum by KONISHI, Atsuko, TAKEGAMI, Shigehiko, IDOSAKI, Yoko, KITADE, Tatsuya

“…A molecularly imprinted polymer-modified potentiometric histamine (HIS) sensor was prepared and used for quantitative determination of HIS in bovine serum. The…”
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A Molecularly Imprinted Polymer-modified Potentiometric Sensor for the Detection of Glutathione by KONISHI, Atsuko, TAKEGAMI, Shigehiko, KITADE, Tatsuya

“…Potentiometric glutathione (GSH) sensors were fabricated using a molecularly imprinted polymer prepared from GSH, methacrylic acid (MAA), and ethylene glycol…”
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Spectroscopic study of cyclen-based 19F NMR probe for detection of hydrogen sulfide by Takegami, Shigehiko, Aramoto, Yuki, Konishi, Atsuko

“…A cyclen-based 19 F NMR probe (F-cyclen) for hydrogen sulfide (H 2 S) has been prepared and evaluated for its complex formation ability with Cu 2+ ions and…”
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Development and validation of an assay method for benzene in the delgocitinib drug substance using conventional HPLC by Nomura, Shinkichi, Ito, Yoshiharu, Takegami, Shigehiko, Kitade, Tatsuya

“…Benzene is a highly toxic solvent that should be limited to no more than 2 ppm in drug substances, as regulated by the International Council for Harmonization…”
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Formation of ionic liquid submicron particles. 1H and 19F nuclear magnetic resonance spectroscopic studies by Takegami, Shigehiko, Watanabe, Kisho, Konishi, Atsuko, Kitade, Tatsuya

“…We prepared novel ionic liquid submicron particles (ILSPs) in water by emulsifying the ionic liquid (IL) N-(2-methoxyethyl)-N-methylpyrrolidinium…”
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Development of trace analysis for alkyl methanesulfonates in the delgocitinib drug substance using GC-FID and liquid–liquid extraction with ionic liquid by Nomura, Shinkichi, Ito, Yoshiharu, Takegami, Shigehiko, Kitade, Tatsuya

“…Alkyl methanesulfonates are genotoxic impurities that should be limited to an intake of not more than 1.5 µg/day, as regulated by the International Council for…”
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Thermal Behavior of 19F Nuclear Magnetic Resonance Signal of 19F-Containing Compound in Lipid Nano-Emulsion for Potential Tumor Diagnosis by Iima, Risa, Takegami, Shigehiko, Konishi, Atsuko, Tajima, Shiori, Minematsu, Nao, Kitade, Tatsuya

“…We developed carriers of a 19 F magnetic resonance imaging ( 19 F MRI) agent, capable of responding to the temperature difference for cancer diagnosis. The…”
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New Approach to Promoting Healthy Life-span with Pharmacies and Pharmaceutical Distributors—To Support the Maintenance and Promotion of Independent Health by Local Residents by Yoshikawa, Yutaka, Takegami, Shigehiko, Inoue, Masateru

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Correction to: Antihypertensive constituents in Sanoshashinto by Wu, Jianbo, Nakashima, Souichi, Shigyo, Marina, Yamasaki, Mutsumi, Ikuno, Sumire, Morikawa, Aoi, Takegami, Shigehiko, Nakamura, Seikou, Konishi, Atsuko, Kitade, Tatsuya, Matsuda, Hisashi

“…The article Antihypertensive constituents in Sanoshashinto, written by Jianbo Wu, Souichi Nakashima, Marina Shigyo, Mutsumi Yamasaki, Sumire Ikuno,…”
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Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection by Matsumoto, Misaki, Sawada, Hikari, Iwata, Kazumi, Ibi, Masakazu, Asaoka, Nozomi, Katsuyama, Masato, Shintani-Ishida, Kaori, Ikegaya, Hiroshi, Takegami, Shigehiko, Umemura, Atsushi, Yabe-Nishimura, Chihiro

“…Various chemical probes for the detection of reactive oxygen species have been developed to examine oxidative stress associated with different pathologies…”
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Antihypertensive constituents in Sanoshashinto by Wu, Jianbo, Nakashima, Souichi, Shigyo, Marina, Yamasaki, Mutsumi, Ikuno, Sumire, Morikawa, Aoi, Takegami, Shigehiko, Nakamura, Seikou, Konishi, Atsuko, Kitade, Tatsuya, Matsuda, Hisashi

“…It has been reported that Sanoshashinto (SanHuangXieXinTang, 三黃瀉心湯), which is composed of Rhei Rhizoma, Scutellariae Radix, and Coptidis Rhizoma, exhibits…”
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Preparation and Characterization of a New Lipid Nano-Emulsion Containing Two Cosurfactants, Sodium Palmitate for Droplet Size Reduction and Sucrose Palmitate for Stability Enhancement by Takegami, Shigehiko, Kitamura, Keisuke, Kawada, Hiroto, Matsumoto, Yu, Kitade, Tatsuya, Ishida, Hiroharu, Nagata, Chieyo

“…A new lipid nano-emulsion (LNE) was prepared from soybean oil and phosphatidylcholine (PC) employing two cosurfactants, sodium palmitate (PA) for reduced…”
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Partitioning of Anti-inflammatory Steroid Drugs into Phosphatidylcholine and Phosphatidylcholine-Cholesterol Small Unilamellar Vesicles as Studied by Second-Derivative Spectrophotometry by Takegami, Shigehiko, Kitamura, Keisuke, Funakoshi, Takako, Kitade, Tatsuya

“…The partition coefficients (Kps) of six anti-inflammatory steroid drugs, dexamethasone (DMS), betamethasone (BMS), triamcinolone acetonide (TCLA), fluocinolone…”
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Potentiometric Immunosensor Using Artificial Antibody Based on Molecularly Imprinted Polymers by Kitade, Tatsuya, Kitamura, Keisuke, Konishi, Tomoyuki, Takegami, Shigehiko, Okuno, Takayoshi, Ishikawa, Michie, Wakabayashi, Manabu, Nishikawa, Kayoko, Muramatsu, Yoko

“…A potentiometric artificial immunosensor based on a molecularly imprinted polymer was prepared as a detecting element in micro total analysis systems with the…”
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Preparation and application of multiple particle binding-liposomes for electrochemiluminescent signal amplification in bioassays by Tanaka, Aki, Konishi, Atsuko, Takegami, Shigehiko

“…In this study, multiple particle binding-liposomes (MPB-Lips), encapsulating the luminophore tris(2′,2-bipyridyl)ruthenium (II) complex ([Ru(bpy) 3 ] 2+ ),…”
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Effects of Inorganic Ions on the Binding of Triflupromazine and Chlorpromazine to Bovine Serum Albumin Studied by Spectrometric Methods by Kitamura, Keisuke, Omran1), Ahmed Ahmed, Nagata, Chieyo, Kamijima, Yoshiko, Tanaka, Rumi, Takegami, Shigehiko, Kitade, Tatsuya

“…The effects of inorganic salts, NaCl, NaBr, NaI, Na2SO4, KCl, KBr, KI, on the binding constants (Ks) of psychotropic phenothiazine drugs, triflupromazine (TFZ)…”
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薬局・医薬品流通業を中心とした健康寿命増進を目指した新たなる取り組み─地域住民による主体的な健康の維持・増進を積極的に支援するためには by 吉川, 豊, 武上, 茂彦, 井上, 正昭

“…2015年9月に厚生労働省が公表した「健康サポート薬局のありかた」の中に「地域の薬局が率先して, 地域住民の健康サポートを積極的・具体的に実施すること」という要件が示されている. さらに健康サポート薬局の重要な役割として「地域住民による『主体的な』健康の維持・増進」があり,…”
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Detection of dopamine levels using a polydiacetylene liposomal aequorin bioluminescent device with octadecylboronic acid by Takegami, Shigehiko, Danzako, Minato, Konishi, Atsuko

“…The development of an easy-to-use and rapid method for the determination of dopamine levels is desirable for the diagnosis of neurological conditions, such as…”
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Effects of Phosphatidylserine and Phosphatidylethanolamine Content on Partitioning of Triflupromazine and Chlorpromazine between Phosphatidylcholine–Aminophospholipid Bilayer Vesicles and Water Studied by Second-Derivative Spectrophotometry by Takegami, Shigehiko, Kitamura, Keisuke, Kitade, Tatsuya, Takashima, Miwa, Ito, Mika, Nakagawa, Eiko, Sone, Midori, Sumitani, Rie, Yasuda, Yumiko

“…To assess the affinity of psychotropic phenothiazine drugs, triflupromazine (TFZ) and chlorpromazine (CPZ), for the membranes of central nervous system and the…”
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