Search Results - "Takeda, Yoshiyu"
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Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021
Published in ENDOCRINE JOURNAL (01-01-2022)“…Primary aldosteronism (PA) is associated with higher cardiovascular morbidity and mortality rates than essential hypertension. The Japan Endocrine Society…”
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Epigenetic Regulation of the Renin-Angiotensin-Aldosterone System in Hypertension
Published in International journal of molecular sciences (01-08-2024)“…Activation of the renin-angiotensin-aldosterone system (RAAS) plays an important pathophysiological role in hypertension. Increased mRNA levels of the ,…”
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DNA Methylation of the Angiotensinogen Gene, AGT , and the Aldosterone Synthase Gene, CYP11B2 in Cardiovascular Diseases
Published in International journal of molecular sciences (27-04-2021)“…Angiotensinogen (AGT) and aldosterone play key roles in the regulation of blood pressure and are implicated in the pathogenesis of cardiovascular diseases. DNA…”
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Molecular and Epigenetic Control of Aldosterone Synthase, CYP11B2 and 11-Hydroxylase, CYP11B1
Published in International journal of molecular sciences (17-03-2023)“…Aldosterone and cortisol serve important roles in the pathogenesis of cardiovascular diseases and metabolic disorders. Epigenetics is a mechanism to control…”
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Primary aldosteronism subtype discordance between computed tomography and adrenal venous sampling
Published in Hypertension research (01-12-2019)“…The primary aldosteronism (PA) subtype is usually confirmed by CT and adrenal venous sampling (AVS). However, the subtype diagnosis by AVS is not necessarily…”
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Comparison of eplerenone and spironolactone for the treatment of primary aldosteronism
Published in Hypertension research (01-03-2016)“…The mineralocorticoid receptor (MR) is expressed in the kidneys and in adipose tissue, and primary aldosteronism (PA) is associated with metabolic syndrome…”
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Significance of Computed Tomography and Serum Potassium in Predicting Subtype Diagnosis of Primary Aldosteronism
Published in The journal of clinical endocrinology and metabolism (01-03-2018)“…The number of centers with established adrenal venous sampling (AVS) programs for the subtype diagnosis of primary aldosteronism (PA) is limited. Aim was to…”
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Adrenal Hemorrhaging in a Patient with Severe Obstructive Sleep Apnea Syndrome with Elevated Plasma ACTH Levels
Published in Internal Medicine (01-08-2023)“…Adrenal hemorrhaging (AH) is a rare condition characterized by bleeding into the suprarenal glands. A 62-year-old man with untreated obstructive sleep apnea…”
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Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism
Published in Endocrine Journal (01-01-2024)“…11Beta-hydroxysteroid dehydrogenase 1 (11β-HSD1) is a key enzyme involved in metabolic syndrome. Transcript-specific epigenetic regulation of the gene encoding…”
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Obesity as a Key Factor Underlying Idiopathic Hyperaldosteronism
Published in The journal of clinical endocrinology and metabolism (01-12-2018)“…Recently, the relationship between primary aldosteronism (PA) and various metabolic disorders, including obesity, diabetes mellitus, and dyslipidemia, has been…”
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Association Between Acute Fall in Estimated Glomerular Filtration Rate After Treatment for Primary Aldosteronism and Long-Term Decline in Renal Function
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Primary aldosteronism causes renal structural damage after glomerular hyperfiltration, and primary aldosteronism-specific treatment leads to an acute fall in…”
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Impact of mineralocorticoid receptor blockade with direct renin inhibition in angiotensin II-dependent hypertensive mice
Published in Hypertension research (01-10-2020)“…It has been suggested that aldosterone breakthrough during treatment with a type 1 angiotensin II receptor (AT1R) blocker (ARB) may be an important risk factor…”
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Impact of salt intake on urinary albumin excretion in patients with type 2 diabetic nephropathy: a retrospective cohort study based on a generalized additive model
Published in Endocrine Journal (01-01-2022)“…Diabetic kidney disease is an important and common cause of end-stage renal disease. Measurement of urinary albumin excretion (UAE) requires the diagnosis of…”
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Effects of eplerenone, a selective mineralocorticoid receptor antagonist, on clinical and experimental salt-sensitive hypertension
Published in Hypertension research (01-05-2009)“…Mineralocorticoid receptors (MRs) are expressed in non-epithelial tissues, such as blood vessels, the heart and adipose tissue. The combined effects of…”
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Effect of sodium glucose cotransporter 2 inhibitors on obstructive sleep apnea in patients with type 2 diabetes
Published in Endocrine Journal (01-01-2018)“…Obstructive sleep apnea syndrome (OSAS) is often associated with metabolic disorders such as obesity and type 2 diabetes and may contribute to cardiovascular…”
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Primary aldosteronism patients with previous cardiovascular and cerebrovascular events have high aldosterone responsiveness to ACTH stimulation
Published in Endocrine Journal (01-01-2024)“…Aldosterone secretion in primary aldosteronism (PA) is often regulated by adrenocorticotropic hormone (ACTH) in addition to its autonomous secretion. However,…”
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Prevalence of primary aldosteronism among prehypertensive and stage 1 hypertensive subjects
Published in Hypertension research (01-01-2011)“…Recent studies have reported a high prevalence of primary aldosteronism among patients with severe hypertension. However, the prevalence of this disease among…”
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Impact of New Quick Gold Nanoparticle-Based Cortisol Assay During Adrenal Vein Sampling for Primary Aldosteronism
Published in The journal of clinical endocrinology and metabolism (01-06-2016)“…Context: Adrenal vein sampling (AVS) is essential for identifying a surgically curable form of primary aldosteronism (PA), but accurate placement of the…”
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Predictor of Steroid Replacement Duration after Removal of Cortisol-producing Adenoma
Published in Internal Medicine (18-10-2024)“…Objective Cortisol-producing adenoma (CPA) is a major subtype of functional adrenal tumors. CPAs are generally treated with adrenalectomy; however, it is…”
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Dynamic regulation of the angiotensinogen gene by DNA methylation, which is influenced by various stimuli experienced in daily life
Published in Hypertension research (01-08-2015)“…Angiotensinogen (AGT) has a central role in maintaining blood pressure and fluid balance. DNA methylation is an epigenomic modification maintaining a steady…”
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