Search Results - "Takeda, Eiji"
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Influenza Virus-Host Interactome Screen as a Platform for Antiviral Drug Development
Published in Cell host & microbe (10-12-2014)“…Host factors required for viral replication are ideal drug targets because they are less likely than viral proteins to mutate under drug-mediated selective…”
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2
Dietary Phosphorus Acutely Impairs Endothelial Function
Published in Journal of the American Society of Nephrology (01-07-2009)“…Excessive dietary phosphorus may increase cardiovascular risk in healthy individuals as well as in patients with chronic kidney disease, but the mechanisms…”
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3
Increasing Dietary Phosphorus Intake from Food Additives: Potential for Negative Impact on Bone Health
Published in Advances in nutrition (Bethesda, Md.) (01-01-2014)“…It is important to consider whether habitual high phosphorus intake adversely affects bone health, because phosphorus intake has been increasing, whereas…”
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4
Dietary phosphorus in bone health and quality of life
Published in Nutrition reviews (01-06-2012)“…Awareness of phosphorus intake is important because both phosphorus deficiency and overloading impair bone health and quality of life. Phosphorus consumption…”
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5
Diaper-zero program (prompted voiding care) improves diaper use in nursing home residents
Published in The Journal of Medical Investigation (2023)“…With an aging population, the number of older adults admitted to nursing homes has increased. Diapers are often used to manage nursing home resident urinary…”
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Clinical Uses of a Robot (Hybrid-Assisted Limb or HAL™) in Patients with Post-stroke Spasticity after Botulinum Toxin Injections
Published in The Journal of Medical Investigation (2021)“…Spasticity is the major cause of disabilities in stroke-survivors. Botulinum neurotoxin (BoNT) injections have been used to reduce the muscle tone in those…”
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7
Comparison of water balance among healthy young and old adults and handicapped adults
Published in The Journal of Medical Investigation (2023)“…The body’s water balance is changed by food and beverage intake, metabolism, and excretion. In this study, we performed a cross-sectional study that…”
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8
Necessity of daily 1000-IU vitamin D supplementation for maintaining a sufficient vitamin D status
Published in The Journal of Medical Investigation (2022)“…The changes in the serum 25-hydroxyvitamin D (25(OH)D) concentrations after daily 1000-IU vitamin D intake for 3 months (3-month-VD), 6 months (6-month-VD) and…”
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Association of increased renal Cyp24a1 gene expression with low plasma 1,25-dihydroxyvitamin D levels in rats with streptozotocin-induced diabetes
Published in Journal of Clinical Biochemistry and Nutrition (01-01-2020)“…Decreases in plasma vitamin D concentrations have been reported in diabetes, although the mechanism involved in this decrease is unclear. Here, we investigated…”
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10
Dietary quercetin inhibits bone loss without effect on the uterus in ovariectomized mice
Published in Journal of bone and mineral metabolism (01-11-2009)“…Quercetin is a major dietary flavonoid found in onions and other vegetables, and potentially has beneficial effects on disease prevention. In the present…”
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Effects of daily 1,000-IU vitamin D-fortified milk intake on skeletal muscle mass, power, physical function and nutrition status in Japanese
Published in The Journal of Medical Investigation (2021)“…An intervention study was conducted to investigate the effects of daily 1,000-IU vitamin D-fortified milk intake on skeletal muscle mass, power, physical…”
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12
Effects of dietary phosphate on glucose and lipid metabolism
Published in American journal of physiology: endocrinology and metabolism (01-04-2016)“…Recent epidemiological and animal studies have suggested that excess intake of phosphate (Pi) is a risk factor for the progression of chronic kidney disease…”
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Relationship between age-related decreases in serum 25-hydroxyvitamin D levels and skeletal muscle mass in Japanese women
Published in The Journal of Medical Investigation (2020)“…A clearer understanding of skeletal muscle mass (SMM) in middle-aged and elderly individuals is important for maintaining functionality. In the present study,…”
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Cut-off values for skeletal muscle strength and physical functions in Japanese elderly with walking difficulty
Published in The Journal of Medical Investigation (2021)“…Age-related changes in muscle strength and physical functions, and the association between vitamin D status and skeletal muscle functions were investigated in…”
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15
Dietary phosphate exacerbates intestinal inflammation in experimental colitis
Published in Journal of Clinical Biochemistry and Nutrition (2017)“…The recent widespread consumption of Western diets and food additives worldwide is associated with excessive inorganic phosphate intake. However, researchers…”
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16
Sterol regulatory element binding protein 1 trans-activates 25-hydroxy vitamin D3 24-hydroxylase gene expression in renal proximal tubular cells
Published in Biochemical and biophysical research communications (02-06-2018)“…The physiological activity of the steroid derived hormone vitamin D is regulated by several enzymatic steps. Both 25-hydroxy vitamin D3 1α-hydroxylase…”
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Quercetin Prevents Unloading-Derived Disused Muscle Atrophy by Attenuating the Induction of Ubiquitin Ligases in Tail-Suspension Mice
Published in Journal of natural products (Washington, D.C.) (22-10-2010)“…The effects of quercetin (1) were investigated on disused muscle atrophy using mice that underwent tail suspension. Periodic injection of 1 into the…”
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18
Recovery of nutritional metabolism after liver transplantation
Published in Nutrition (Burbank, Los Angeles County, Calif.) (2015)“…Abstract Objective Perioperative nutritional assessment is critically important to reflect nutritional management because liver transplantation (LTx) often is…”
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The age-related changes of dietary phosphate responsiveness in plasma 1,25-dihydroxyvitamin D levels and renal Cyp27b1 and Cyp24a1 gene expression is associated with renal α-Klotho gene expression in mice
Published in Journal of Clinical Biochemistry and Nutrition (01-01-2018)“…In this study, we investigated the relationship between age-related changes in renal α-Klotho gene expression, vitamin D metabolism and the responsiveness of…”
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Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?
Published in PloS one (01-08-2011)“…Fibroblast growth factor 21 (FGF21) has recently emerged as a metabolic hormone involved in regulating glucose and lipid metabolism in mouse, but the…”
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