Search Results - "Takayanagi, Takehiko"

Potential arrhythmic substrate of atrial fibrillation at the left atrial diverticulum by Takayanagi, Takehiko

“…Catheter ablation therapy for persistent atrial fibrillation (PeAF) is both difficult and has limited outcomes. The mechanisms underlying the development and…”
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Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II by Takayanagi, Takehiko, Forrester, Steven J, Kawai, Tatsuo, Obama, Takashi, Tsuji, Toshiyuki, Elliott, Katherine J, Nuti, Elisa, Rossello, Armando, Kwok, Hang Fai, Scalia, Rosario, Rizzo, Victor, Eguchi, Satoru

“…Angiotensin II (AngII) has been strongly implicated in hypertension and its complications. Evidence suggests the mechanisms by which AngII elevates blood…”
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Role of Epidermal Growth Factor Receptor and Endoplasmic Reticulum Stress in Vascular Remodeling Induced by Angiotensin II by Takayanagi, Takehiko, Kawai, Tatsuo, Forrester, Steven J, Obama, Takashi, Tsuji, Toshiyuki, Fukuda, Yamato, Elliott, Katherine J, Tilley, Douglas G, Davisson, Robin L, Park, Joon-Young, Eguchi, Satoru

“…The mechanisms by which angiotensin II (AngII) elevates blood pressure and enhances end-organ damage seem to be distinct. However, the signal transduction…”
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Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model by Obama, Takashi, Tsuji, Toshiyuki, Kobayashi, Tomonori, Fukuda, Yamato, Takayanagi, Takehiko, Taro, Yoshinori, Kawai, Tatsuo, Forrester, Steven J, Elliott, Katherine J, Choi, Eric, Daugherty, Alan, Rizzo, Victor, Eguchi, Satoru

“…Angiotensin II (Ang II) has been implicated in the development of abdominal aortic aneurysm (AAA). In vascular smooth muscle cells (VSMC), Ang II activates…”
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Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase by Takayanagi, Takehiko, Crawford, Kevin J, Kobayashi, Tomonori, Obama, Takashi, Tsuji, Toshiyuki, Elliott, Katherine J, Hashimoto, Tomoki, Rizzo, Victor, Eguchi, Satoru

“…Although AngII (angiotensin II) and its receptor AT1R (AngII type 1 receptor) have been implicated in AAA (abdominal aortic aneurysm) formation, the proximal…”
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Constitutive Stimulation of Vascular Smooth Muscle Cells by Angiotensin II Derived From an Adenovirus Encoding a Furin-Cleavable Fusion Protein by Takayanagi, Takehiko, Bourne, Allison M., Kimura, Keita, Takaguri, Akira, Elliott, Katherine J., Eguchi, Kunie, Eguchi, Satoru

“…Background: To fill the gap between acute and chronic stimulation methods of angiotensin II (Ang II) and obtain relevant signaling information, we have made an…”
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A repressor protein, Mnt, is a novel negative regulator of vascular smooth muscle cell hypertrophy by angiotensin II and neointimal hyperplasia by arterial injury by Takayanagi, Takehiko, Eguchi, Akito, Takaguri, Akira, Hinoki, Akinari, Bourne, Allison M, Elliott, Katherine J, Hurlin, Peter J, Eguchi, Satoru

“…Abstract Objective The Max-interacting protein Mnt is a transcriptional repressor that can antagonize the transcriptional and proliferation-related activities…”
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A New Enteral Diet, MHN-02, Which Contains Abundant Antioxidants and Whey Peptide, Protects Against Carbon Tetrachloride–Induced Hepatitis by Takayanagi, Takehiko, Sasaki, Hajime, Kawashima, Akihiro, Mizuochi, Yuichiro, Hirate, Hiroyuki, Sugiura, Takeshi, Azami, Takafumi, Asai, Kiyofumi, Sobue, Kazuya

“…Background: Inflammatory or oxidative stress is related to various diseases, including not only inflammatory diseases, but also diabetes, cancer, and…”
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Inhibition of Prolyl Hydroxylase Domain-Containing Protein: A Novel Therapy for Cardiovascular Diseases? by Takayanagi, Takehiko, Eguchi, Satoru

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EC for 167106: Inhibition of prolyl hydroxylase domain-containing protein: a novel therapy for cardiovascular diseases? by Takayanagi, Takehiko, Eguchi, Satoru

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Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile–Induced Abdominal Aortic Aneurysm by Kawai, Tatsuo, Takayanagi, Takehiko, Forrester, Steven J, Preston, Kyle J, Obama, Takashi, Tsuji, Toshiyuki, Kobayashi, Tomonori, Boyer, Michael J, Cooper, Hannah A, Kwok, Hang Fai, Hashimoto, Tomoki, Scalia, Rosario, Rizzo, Victor, Eguchi, Satoru

“…Angiotensin II (AngII)–activated epidermal growth factor receptor has been implicated in abdominal aortic aneurysm (AAA) development. In vascular smooth muscle…”
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Abstract 012: Vascular Smooth Muscle ADAM17 Contributes to Angiotensin II-induced Abdominal Aortic Aneurysm Formation but Not Hypertension in Mice by Kawai, Tatsuo, Takayanagi, Takehiko, Preston, Kyle J, Forrester, Steven J, Scalia, Rosario, Rizzo, Victor, Eguchi, Satoru

“…Abstract only Over activation of the renin angiotensin II (AngII) system has been implicated in abdominal aortic aneurysm (AAA). However, the precise molecular…”
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ADAM17 silencing by adenovirus encoding miRNA-embedded siRNA revealed essential signal transduction by angiotensin II in vascular smooth muscle cells by Elliott, Katherine J, Bourne, Allison M, Takayanagi, Takehiko, Takaguri, Akira, Kobayashi, Tomonori, Eguchi, Kunie, Eguchi, Satoru

“…Abstract Small interfering RNA (siRNA) mediated gene silencing has been utilized as a powerful molecular tool to study the functional significance of a…”
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Abstract P223: Caveolin-1 Contributes to Vascular Remodeling and Inflammation Induced by Angiotensin Ii in vivo and in vitro by Kawai, Tatsuo, Forrester, Steven J, Elliot, Katherine J, Obama, Takashi, Takayanagi, Takehiko, Crawford, Kevin, Eguchi, Satoru, Rizzo, Victor

“…Abstract only We have recently reported that caveolin-1 (Cav1) enriched membrane microdomains in vascular smooth muscle cells (VSMC) mediate a metalloprotease…”
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Vascular Induction of a Disintegrin and Metalloprotease 17 by Angiotensin II Through Hypoxia Inducible Factor 1α by Obama, Takashi, Takayanagi, Takehiko, Kobayashi, Tomonori, Bourne, Allison M., Elliott, Katherine J., Charbonneau, Martine, Dubois, Claire M., Eguchi, Satoru

“…BACKGROUND A disintegrin and metalloprotease 17 (ADAM17) is a membrane-spanning metalloprotease overexpressed in various cardiovascular diseases such as…”
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Abstract 279: Role of Caveolin-1 in Abdominal Aortic Aneurysm induced by Angiotensin II by Takayanagi, Takehiko, Crawford, Kevin, Kobayashi, Tomonori, Rizzo, Victor, Eguchi, Satoru

“…Abstract only Abdominal aortic aneurysm (AAA) is a significant cause of mortality for adults aged >60 years. Accumulating evidence suggests that activation of…”
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Abstract 9: Involvement of Caveolin-1 in Vascular Remodeling and Inflammation Induced by Angiotensin II by Forrester, Steven J, Kawai, Tatsuo, Elliott, Katherine J, Obama, Takashi, Takayanagi, Takehiko, Crawford, Kevin, Eguchi, Satoru, Rizzo, Victor

“…Abstract only We have recently reported that caveolin-1 (Cav1) enriched membrane microdomains in vascular smooth muscle cells (VSMC) mediate a metalloprotease…”
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Role of Caveolae in the development of abdominal aortic aneurysms by Crawford, Kevin, Takayanagi, Takehiko, Eguchi, Satoru, Rizzo, Victor

“…Abstract only Abdominal aortic aneurysm (AAA) is a major cardiovascular disease and involves enhancement of rennin‐angiotensin system and…”
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Abstract 019: Vascular Smooth Muscle ADAM17 Contributes To Angiotensin II-induced Abdominal Aortic Aneurysm Formation But Not Hypertension In Mice by Tsuji, Toshiyuki, Takayanagi, Takehiko, Elliott, Katherine, Obama, Takashi, Crawford, Kevin, Rizzo, Victor, Eguchi, Satoru

“…Enhancement of the renin angiotensin II (AngII) system has been implicated in the development of abdominal aortic aneurysm (AAA). However, detailed molecular…”
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Abstract 097: EGF Receptor And ER Stress Mediate End-organ Damage But Not Hypertension Induced By Angiotensin II In Mice by Elliott, Katherine J, Tsuji, Toshiyuki, Obama, Takashi, Takayanagi, Takehiko, Forrester, Steven, Park, Joon, Eguchi, Satoru

“…In cultured vascular smooth muscle cells (VSMC), a metalloprotease ADAM17-dependent EGF receptor (EGFR) activation mediates ERK1/2 activation and subsequent…”
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